Special Issue "Metal-Based Drugs and Nanostructured Materials: New Trends in Bioactive Systems"
Deadline for manuscript submissions: closed (31 August 2020).
Interests: nanomaterials; catalysis; photocatalysis; anticancer; metallodrugs
Special Issues and Collections in MDPI journals
Metal complexes are the basis of a wide variety of topics in Chemistry. For example, they are a current alternative for the treatment, diagnosis and marking of different diseases, constituting an interesting field of study in Medicinal Chemistry, Chemical Biology and Pharmaceutical Sciences.
However, metal complexes present a high number of drawbacks owing to their hydrophobic nature, low water solubility, limited stability and toxicity. Several strategies are now explored for the enhancement of the applicability of metal-based drugs in diagnosis and therapy.
In this context, nanostructured materials can protect metal-based drugs and help them to efficiently interact with biomolecules on surfaces and inside the cells, safely transporting drug molecules to target cells. In addition, nanostructures (lipid nanocapsules, polymeric nanoparticles, inorganic nanostructures, etc.) either encapsulating and protecting metallodrugs or as single nanosystems can ensure the proper and safe delivery of poorly water-soluble drugs or other agents.
In this context, this special issue will try to cover the most recent and cutting edge strategies on the support and encapsulation of metal complexes in nanosystems with therapeutic purposes.
The contributions of this Special Issue should be covering (but not limited to) the following topics:
- The most recent synthetic methods for the preparation of novel metallodrugs and/or metallodrug-supported nanomaterials
- Study of the therapeutic properties (in vitro or in vivo) of improved metal-based drugs and nanostructured materials functionalized with therapeutic metal complexes.
- Analysis of the application of metal-based drugs or nanostructured materials in cell imaging or diagnosis
- Study of the improvement of the bioavailability of metal-based drugs with the use of nanostructures as encapsulators.
Prof. Dr. Santiago Gómez-Ruiz
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Pharmaceutics is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1800 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- metal-based drugs
- nanostructured materials