Intranasal Drug Delivery Systems

Dear Colleagues,

In recent years, intranasal (IN) drug delivery has become the focus of attention. IN administration is an effective way to deliver drugs into the systemic circulation (nose-to-blood delivery), resulting in rapid onset. However, we have less knowledge about nose-to-brain delivery where the nasal pathway may bypass the blood–brain barrier and allow centrally acting pharmacons to directly enter the central nervous system. IN drug delivery (particularly targeting specific tissues within the brain) will gain more importance.  The major challenge in IN drug delivery is getting to know the physicochemical properties of mucus and its impact on transmucosal drug delivery (mucus penetrating drug delivery). The physicochemical properties of the drugs fundamentally determine the IN transport, and, therefore, their modification or use of nanotechnology-based carriers are required.
The scope of this Special Issue is to present IN drug delivery systems/technologies that are related to the IN mucus penetrating particle delivery and nose-to-blood as well as nose-to-brain transports. We also welcome manuscripts related to quality assurance and the regulatory environment related to this topic.
We are looking forward to your related publications, hoping that this Special Issue improves our understanding of how the IN drug delivery systems work.

Prof. Dr. Piroska Szabó-Révész
Prof. Dr. Ildikó Csóka
Prof. Dr. Rita Ambrus
Guest Editors

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