Special Issue "Functional Polymers for Controlled Drug Release"
A special issue of Pharmaceutics (ISSN 1999-4923).
Deadline for manuscript submissions: 31 July 2019
Prof. Umile Gianfranco Spizzirri
University of Calabria, Department of Pharmacy, Health and Nutritional Sciences, Cosenza, Italy
Interests: stimuli-responsive drug delivery systems, munti-functional hydrogels, antioxidant polymers
In the last decade, high-performing functional polymers for specific uses, including stimuli-responsive materials, molecularly imprinted polymers, mucoadhesive materials, carriers for the delivery of high MW drugs, and gene-delivery have emerged as one of the most significant trends in the area of nanotechnology. In this regard, polymeric devices that are able to undergo morphological modifications in response to an external stimulus (pH, redox balance, temperature, magnetic field, and light) represent an innovative field in the delivery of therapeutics. Additionally, in an effort to further improve delivery device performance, a combination of two or more signals have recently been developed by incorporating different stimulus responsive elements into the same polymeric network with the aim to improve the situ-controlled delivery of bioactive compounds. These smart polymeric materials lead to superior in vitro and/or in vivo therapeutic efficacy, with programmed site-specific features and remarkable potential for targeted therapy. Specifically, the correlation between the physical features and the situ-controlled delivery of bioactive compounds represents an important aspect worthy of investigation. This Special Issue welcomes any topics regarding recent progress in the synthesis and characterization of innovative functional polymers suitable to be employed as drug carriers in the pharmaceutical and biomedical fields.
Prof. Umile Gianfranco Spizzirri
Manuscript Submission Information
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- Functional polymer
- Drug delivery
- External stimulus
- Site-specific release