Dear Colleagues,

We are pleased to invite you to submit your original research and review papers for publication in this Special Issue of Pharmaceutics, titled “Functionalization of Carbon Nanomaterials for Antineoplastic Applications“. The necessity for a reduction in the undesired side effects of antineoplastics has led to a new approach: the application of the drug in the form of carbon nanoformulations. Interdisciplinary research engaged in the determination of novel carbon nanocarrier/antineoplastic nanoformulation structures and the molecular mechanisms responsible for their actions and effects represent the main scientific challenge in this Special Issue.

This Special Issue aims to present the results obtained so far and to make some predictions in the field of functionalized carbon nanomaterials used for antineoplastic applications. First, the focus will be on the synthesis and characterization of novel nanoformulations of functionalized carbon nanomaterials as antineoplastic carriers, and defining the intermolecular interactions of carbon nanocarriers/drug. Especially valued will be studies relating to the simplicity of synthesis procedures and the stability of nanoformulations in physiological conditions (in vitro and in vivo), with an increased therapeutic index of nanoformulation compared with the drug itself, pharmacokinetic parameters and pharmacodynamic effects, together with controlled-release effects. Interdisciplinary biological research contributing to the interpretation of underlying complex molecular mechanisms is of particular interest and importance to this Special Issue.

Original research articles and novel reviews are welcome in this Special Issue. Research areas may include (but are not limited to) the following: new synthesis of carbon-based nanoformulations with anticancer drugs, experimental and theoretical physico-chemical characterization and determination of carbon nanocarrier/antineoplastic interactions, stability in physiological conditions, reduction of side effects, development of targeted delivery systems, controlled release, investigation of molecular mechanisms underlying interactions with different biological systems, the results of pharmacokinetic and pharmacodynamic studies, potential pharmaceutical formulations, in vitro and in vivo studies, and clinical research.

I look forward to receiving your contributions.

Prof. Dr. Aleksandar Đorđević
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Pharmaceutics is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

• carbon-based nanomaterials
• antineoplastic
• synthesis and characterisation of nanoformulation
• nanocarbon–drug interaction
• stability of nanoformulation
• molecular mechanisms
• delivery and controlled release
• pharmacodynamics
• pharmacokinetics
• in vitro and in vivo research