Dosage Form Formulation Technologies for Improving Bioavailability

Dear Colleagues,

The challenges of drug development could be extremely tough, high risk of failure or non-approval competes with the great benefits following the successful marketing authorization of a new molecular entities. Therefore, the more effective formulation in dosage form design is vital to overcome the possible disadvantageous physicochemical or biopharmaceutical properties of an approved API. Improving the oral, transdermal, or parenteral bioavailability relying on rational dosage form design or redesign, even after years of the market launch would increase therapeutic efficacies or patient compliance and lower the severity and the occurrence of unwanted side-effects. Innovative techniques, technological applications together with recently developed excipients would open the doors to the global markets for more patient-friendly products.

This Special Issue welcomes original research papers especially, but not limited to cooperative works between academia and pharmaceutical companies, where reformulations or original dosage form design were performed. Papers or reviews including the principles of Quality by Design to improve the bioavailability of drug belonging to BCS Classes of II or IV are warmly encouraged for submission. We are looking for manuscripts that optimize the innovative technology by the design of experiments as well. Non-pharma institutes or departments and their innovative research projects are also invited to contribute this Special Issue, if their novel and original results could be adapted to dosage form formulation or production.

Dr. Gábor Vasvári
Dr. Ádám Haimhoffer
Guest Editors

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