Pharmaceuticals

Design, Synthesis and Pharmacological Evaluation of Novel Opioid/Non-Opioid Hybrid Compounds

edited by Justyna Piekielna-Ciesielska and

Katarzyna Gach-Janczak

submission deadline 31 Mar 2026 | Viewed by 134 | Submission Open

Keywords: opioid; opioid hybrids; pain; opioid-related side-effects; tolerance; addiction; neurotransmitters

(This special issue belongs to the Section Medicinal Chemistry)

Membrane Receptors in Disease: Mechanisms and Targeted Therapeutic Strategies

edited by

Robson Xavier Faria

submission deadline 31 Mar 2026 | Viewed by 71 | Submission Open

Keywords: membrane receptors; targeted drug; signal transduction; therapeutic antibodies; inhibitor; synthetic

(This special issue belongs to the Section Pharmacology)

Bioactive Natural Extracts: Advances in Pharmacological and Therapeutic Research

edited by

Gabriela-Maria Baci

and

Victorița Bonta

submission deadline 1 Apr 2026 | 1 articles | Viewed by 430 | Submission Open

Keywords: bioactive compounds; natural extracts; pharmacological activity; drug discovery; plant-derived compounds

(This special issue belongs to the Section Natural Products)

Advances in Ophthalmic Drug Discovery and Delivery: From Targets to Treatments

edited by

Hongli Wu

submission deadline 10 Apr 2026 | 4 articles | Viewed by 6944 | Submission Open

Keywords: retinal degeneration; glaucoma; cataract; diabetic retinopathy; drug target; drug delivery; drug candidate; gene therapy; stem cells; natural products; Artificial Intelligence

(This special issue belongs to the Section Pharmacology)

Emerging Therapeutics for the Prevention of Chemotherapy-Induced Cardiotoxicity: Advances and Future Perspectives

edited by

Luigi Spadafora

,

Marco Bernardi

, Sarto Sarto and

Vincenzo Quagliariello

submission deadline 20 Apr 2026 | 3 articles | Viewed by 7539 | Submission Open

Keywords: cardio-oncology; chemotherapy-induced cardiotoxicity; cardioprotective agents; biomarkers; heart failure prevention; precision medicine; pharmacological innovation; molecular targets; cancer survivorship; multidisciplinary care

(This special issue belongs to the Section Pharmacology)

Next-Generation Targeted Therapy: vNARs as Drug Carriers and Intracellular Neutralizing Agents

edited by

Tanya Camacho-Villegas

and

Mirna Burciaga-Flores

submission deadline 20 Apr 2026 | Viewed by 267 | Submission Open

Keywords: vNAR; drug delivery; intrabodies; payload; nanotechnology; immunotoxins; phage display; biopanning; single-domain antibody

(This special issue belongs to the Section Pharmacology)

Targeting Enzymes in Drug Design and Discovery

edited by

Mariyana Atanasova

submission deadline 20 Apr 2026 | Viewed by 179 | Submission Open

Keywords: drug design; computer-aided drug design (CADD); molecular docking; molecular dynamics; QSAR; druggable proteins; synthesis; in vitro and in vivo activity evaluations; ADMET predictions and evaluations

(This special issue belongs to the Section Biopharmaceuticals)

Biosimilars in Oncology: Applications in Pharmaceutics and Pharmaceuticals

edited by Jacopo Giuliani

submission deadline 20 Apr 2026 | Viewed by 65 | Submission Open

Keywords: biosimilars; oncology; randomized controlled trials; pharmacokinetics; pharmacodynamics

(This special issue belongs to the Section Biopharmaceuticals)

Design and Synthesis of Compounds with Potential Anti-Inflammatory Activity

edited by

Aleksandra Redzicka

,

Beata Tylińska

and Anna Wójcicka

submission deadline 22 Apr 2026 | Viewed by 172 | Submission Open

Keywords: drug design; synthesis; anti-inflammatory activity; cyclooxygenases; lipoxygenases; cytokines; anticancer activity; Alzheimer's disease; neuroinflammation; molecular mechanisms

(This special issue belongs to the Section Medicinal Chemistry)

Advanced Nanosystems and Emerging Therapies: Innovations in Tuberculosis Treatment and Drug Resistance

edited by

Fernando Rogério Pavan

and

Cesar Augusto Roque-Borda

submission deadline 24 Apr 2026 | 2 articles | Viewed by 3476 | Submission Open

Keywords: nanosystems; tuberculosis therapy; drug delivery; multidrug-resistant Mycobacterium tuberculosis (MDR-TB); nanotechnology-based therapeutics

(This special issue belongs to the Section Pharmaceutical Technology)

Use of Encapsulating Polymers of Active Compounds in the Pharmaceutical Industry

edited by Alba Adriana Vallejo-Cardona, Inocencio Higuera-Ciapara and

Janna Douda

submission deadline 24 Apr 2026 | 1 articles | Viewed by 3076 | Submission Open

Keywords: polymer; drug delivery; active compounds; encapsulation; pharmaceutical industry; natural polymers; synthetic polymers

(This special issue belongs to the Section Pharmaceutical Technology)

Medicinal Chemistry of Metal Complexes: Design, Synthesis and Evaluation

edited by

Bojana B. Zmejkovski

,

Goran Kaluđerović

and

Nebojša Pantelić

submission deadline 24 Apr 2026 | 1 articles | Viewed by 2661 | Submission Open

Keywords: metal complexes; medicinal chemistry; bioinorganic chemistry; coordination chemistry; organometallics; metal-based drugs; biological activity; toxicology; biomedical application; drug delivery

(This special issue belongs to the Section Medicinal Chemistry)

Recent Advances in Psychopharmacology: 2nd Edition

edited by Roos Van Westrhenen and Allan H. Young

submission deadline 24 Apr 2026 | Viewed by 259 | Submission Open

Keywords: psychopharmaca; pharmacogenomics; pharmacogenetics; psychedelics; dementia drugs

(This special issue belongs to the Section Pharmacology)

Targeting Neuromodulators: Effective Therapeutic Strategies for Brain Disorders

edited by

Jana Tchekalarova

submission deadline 24 Apr 2026 | Viewed by 122 | Submission Open

Keywords: neuromodulators; brain disorders; targets; dysfunctional networks; dopamine; serotonin

(This special issue belongs to the Section Pharmacology)

Applications of Beehive Products for Wound Repair and Skin Care

edited by Simona Martinotti

submission deadline 25 Apr 2026 | 3 articles | Viewed by 22006 | Submission Open

Keywords: anti-aging; antibacterial properties; healing properties; honey; propolis; bee venom; wound repair; skin care

(This special issue belongs to the Section Natural Products)

Pharmacology of Antidepressants: Recent Advances

edited by

Anna Wiktorowska-Owczarek

submission deadline 25 Apr 2026 | 4 articles | Viewed by 20339 | Submission Open

Keywords: new mechanisms of antidepressants action; new targets for antidepressant therapy; rapid-acting antidepressants; inflammation in depression; gut– microbiota– brain axis in depression; probiotic as an antidepressant; quo vadis pharmacology of antidepressants

(This special issue belongs to the Section Pharmacology)

New Development in Pharmacotherapy of Kidney Diseases

edited by Chihchao Yang

submission deadline 25 Apr 2026 | 4 articles | Viewed by 11180 | Submission Open

Keywords: chronic kidney disease (CKD); acute kidney injury (AKI); pharmacotherapy; cardiovascular protection; kidney protection; bone health; endocrine function; gut health; metabolism; neuromuscular function; nutrition; symptom management; sodium-glucose cotransporter-2 (SGLT-2) inhibitors; glucagon-like peptide-1 (GLP-1) receptor agonists; non-steroidal mineralocorticoid receptor antagonists (MRA); endothelin receptor antagonists; anemia management; electrolyte abnormalities; dialysis; nephrotoxicity; drug interactions; uremic toxin; clinical trials; innovative therapies; protein-energy wasting; chronic kidney disease and bone mineral disease; inflammation; oxidation; diabetes; hypertension; obesity; hyperlipidemia; pruritus; osteoporosis; fracture; sarcopenia; protein-energy wasting

(This special issue belongs to the Section Pharmacology)

Potential Therapeutic Targets for the Management of Diabetes Mellitus, Obesity and Cancer

edited by Marisa Jádna Silva Frederico and

Fátima Regina Mena Barreto Silva

submission deadline 25 Apr 2026 | 4 articles | Viewed by 9020 | Submission Open

Keywords: diabetes; obesity; cancer; pharmacological targets

(This special issue belongs to the Section Pharmacology)

Sustainable Approaches and Strategies for Bioactive Natural Compounds

edited by

Annalisa Santucci

, Alfonso Trezza and

Anna Visibelli

submission deadline 25 Apr 2026 | 3 articles | Viewed by 9004 | Submission Open

Keywords: natural compounds; sustainability; biochemical approaches; computational biology; molecular docking; machine learning; systems biology; bioactive molecules

(This special issue belongs to the Section Natural Products)

Pharmacovigilance Insights: Addressing Drug Misuse and Enhancing Drug Safety

edited by

Cristina Sofia De Jesus Monteiro

and

Samuel Martins Silvestre

submission deadline 25 Apr 2026 | 5 articles | Viewed by 7756 | Submission Open

Keywords: adverse drug reaction; pharmacovigilance; drug safety; signal detection; risk management

(This special issue belongs to the Section Pharmacology)

Computer-Aided Drug Design and Drug Discovery, 2nd Edition

edited by

Dragos Mihai

and

George Mihai Nitulescu

submission deadline 25 Apr 2026 | 5 articles | Viewed by 7626 | Submission Open

Keywords: chemoinformatics; bioinformatics; molecular modeling; virtual screening; molecular docking; quantitative structure– activity relationship (QSAR); pharmacophore modeling; target identification; repurposing; ADME-T prediction

(This special issue belongs to the Section Medicinal Chemistry)

Fighting Tropical Neglected Diseases with Natural Products: New Approaches Against Ancient Diseases

edited by

Igor Rodrigues

,

André Luis Souza dos Santos

, Dirlei Nico and Ana Claudia Fernandes Amaral

submission deadline 25 Apr 2026 | 3 articles | Viewed by 7398 | Submission Open

Keywords: plant extracts; natural compounds; neglected diseases; drug resistance; natural product-based formulations; antiparasitic drugs; enzyme inhibition

Combating Drug Resistance in Cancer

edited by

Nina Rembiałkowska

and

Wojciech Szlasa

submission deadline 25 Apr 2026 | 3 articles | Viewed by 5138 | Submission Open

Keywords: multidrug resistance; cancer cells; cancer drug resistance; overcoming chemoresistance; targeted cancer therapies; novel anti-cancer strategies; tumor resistance mechanisms; innovative cancer treatments; reversing drug resistance

(This special issue belongs to the Section Medicinal Chemistry)

Advances in the Treatment of Leukemia, Lymphomas and Plasma Cell Disorders

edited by

Adriano de Paula Sabino

, Karina Braga Gomes and Maria Das Graças Carvalho

submission deadline 25 Apr 2026 | 2 articles | Viewed by 2847 | Submission Open

Keywords: leukemias; lymphomas; chemotherapy; target therapy; immunotherapy; kinase inhibitors; hematologic oncology; therapy; treatment

(This special issue belongs to the Section Medicinal Chemistry)

QSAR and Chemoinformatics in Drug Design and Discovery

edited by

Elena Cichero

and

Naomi Scarano

submission deadline 25 Apr 2026 | 3 articles | Viewed by 2750 | Submission Open

Keywords: QSAR modeling; machine learning; ligand-based virtual screening and design; computer-aided drug repurposing; computational methods; molecular modeling; molecular dynamics; drug design

(This special issue belongs to the Section Medicinal Chemistry)

Pharmaceutical Approaches to Orofacial Pain and Chronic Pain Conditions

edited by

Takahiko Nagamine

submission deadline 25 Apr 2026 | 1 articles | Viewed by 2301 | Submission Open

Keywords: chronic orofacial pain; pharmaceutical approach; myofascial orofacial pain; temporomandibular joint pain; neurovascular orofacial pain; idiopathic orofacial pain; burning mouth syndrome; persistent idiopathic facial pain; persistent idiopathic dentoalveolar pain; tricyclic antidepressants; serotonin reuptake inhibitors; anticonvulsants

(This special issue belongs to the Section Pharmacology)

Therapies for Autoimmune Diseases

edited by

Athanasios Sachinidis

and

Carlo Perricone

submission deadline 25 Apr 2026 | Viewed by 1732 | Submission Open

Keywords: autoimmune diseases; immunotherapy; immunomodulation; biologic therapies; small molecule drugs; therapeutic vaccines; tolerogenic strategies; monoclonal antibodies; personalized medicine; targeted drug delivery

(This special issue belongs to the Section Medicinal Chemistry)

Epithelial Plasticity and Therapy Resistance in Cancer

edited by Naisana Seyedasli

submission deadline 25 Apr 2026 | 1 articles | Viewed by 1374 | Submission Open

Keywords: cancer stem cells; epithelial– mesenchymal transition; epithelial reprogramming; resistance; drug targets; resistance mechanisms; biomarker discovery

(This special issue belongs to the Section Pharmacology)

Pleiotropic Agents and Their Therapeutic Potential in Gastroenterology, Angiology, and Musculoskeletal Disorders

edited by

Predrag Sikirić

, Mario Starešinić,

Anita Skrtic

and Alenka Boban Blagaic

submission deadline 25 Apr 2026 | 1 articles | Viewed by 1170 | Submission Open

Keywords: pleiotropic agents; therapeutic potential; tissue repair; angiogenesis; gastroenterology; musculoskeletal disorders

(This special issue belongs to the Section Biopharmaceuticals)

The Development and Application of Broad-Spectrum Antiviral Drugs

edited by Chieh-Wen Lo

submission deadline 25 Apr 2026 | 1 articles | Viewed by 986 | Submission Open

Keywords: broad-spectrum antiviral; direct-acting antiviral; host-targeted antiviral; emerging viruses; pandemic preparedness

(This special issue belongs to the Section Medicinal Chemistry)

Synthesis and Anticancer Activity of Biologically Active Heterocyclic Compounds

edited by

Birutė Grybaitė

and Rita Vaickelionienė

submission deadline 25 Apr 2026 | 1 articles | Viewed by 774 | Submission Open

Keywords: heterocyclic compounds; five- or six-membered heterocycles; oxygen- and nitrogen-based heterocycles; sulfur- and nitrogen-based heterocycles; azoles; small molecules; anticancer activity; cell lines; cytotoxicity

(This special issue belongs to the Section Medicinal Chemistry)

Endocrine Diseases and Pharmacogenomics

edited by

Leonidas A. Phylactou

,

Vassos Neocleous

and

Pavlos Fanis

submission deadline 25 Apr 2026 | Viewed by 513 | Submission Open

Keywords: inherited endocrine disorders; pharmacogenomics; pharmacogenetics; genome sequencing; clinical trials

(This special issue belongs to the Section Pharmacology)

Research on Diagnosis, Treatment and Related Microbiota in Gastrointestinal Diseases

edited by

Edoardo V. Savarino

and Brigida Barberio

submission deadline 25 Apr 2026 | Viewed by 485 | Submission Open

Keywords: gut microbiota; inflammatory bowel disease; eosinophilic esophagitis; primary sclerosing cholangitis; metabolic-associated steatotic liver disease; immune checkpoint inhibitor colitis; dysbiosis; prebiotics; probiotics

(This special issue belongs to the Section Medicinal Chemistry)

Next-Generation Approaches for Cartilage Regeneration

edited by

Valeria Graceffa

and Liam Morris

submission deadline 25 Apr 2026 | 1 articles | Viewed by 422 | Submission Open

Keywords: cartilage regeneration; cartilage engineering; bioactive molecules (peptides/proteins/nucleic acids); biomaterials (therapeutic delivery); gene engineering (biopharmaceutical applications); chondrogenic signaling pathways; preclinical/clinical evaluation (cartilage repair); osteoarthritis (therapeutic interventions); therapeutic targets (cartilage repair); translational regenerative medicine

(This special issue belongs to the Section Biopharmaceuticals)

Natural Products and Phytomedicines: From Chemical Profiling and Pharmacological Properties to Therapeutic Applications

edited by

Jorge P. Machado

,

Maria Helena Chéu

and

Maria Begoña Criado

submission deadline 25 Apr 2026 | Viewed by 330 | Submission Open

Keywords: natural products and derivatives; (nano)phytomedicine; plant extracts and phytopreparates; biochemical profiling; active principles; phytopharmacological mechanisms; signaling pathways; network pharmacology; molecular docking; pharmacokinetics and toxicity assays; clinical studies; therapeutic novelty; sustainable development

(This special issue belongs to the Section Natural Products)

Synthesis, In Silico Prediction and Antitumor Activity of Nitrogen Heterocycle-Based Drug Development

edited by Jamerson F. De Oliveira and Paulo André Teixeira de Moraes Gomes

submission deadline 25 Apr 2026 | Viewed by 236 | Submission Open

Keywords: privileged structures; nitrogen heterocycles; ADMET prediction; cancer biological target; molecular dynamic; computational studies; antitumor activity; in vitro and in vivo studies; SAR of lead compounds; molecular hybridization

(This special issue belongs to the Section Medicinal Chemistry)

Cholinesterases—Structure, Mechanism, Function and Drug Discovery

edited by

Carmen L. Cardoso

submission deadline 25 Apr 2026 | Viewed by 221 | Submission Open

Keywords: cholinesterases; cholinesterase inhibitors; structure-based design of inhibitors; multi-target ligands; non-cholinergic functions; structure; allosteric sites; mechanism; non-classical functions

(This special issue belongs to the Section Medicinal Chemistry)

Advances in and Perspectives on Oral Drug Delivery

edited by

Laxman Subedi

and

Mohammad Imran

submission deadline 25 Apr 2026 | Viewed by 201 | Submission Open

Keywords: enhanced drug delivery; oral route; oral peptide delivery; 3D printing; continuous manufacturing; PBPK modeling; nanocarriers; translational pharmaceutics; low aqueous solubility and low permeability; enhanced oral bioavailability; transporter targeting; emerging materials and excipients in oral delivery; dosage form transition of already marketed drugs; examining herbal or traditional drugs oral delivery; sustained release; nanotechnology; application of cellular components such as exosomes or vesicles for oral delivery; in silico docking for PBPK; nanocarriers; lipid-based formulations; self-emulsifying drug delivery systems (SEDDS); solid dispersions; mucoadhesive systems

(This special issue belongs to the Section Pharmaceutical Technology)

Pharmaceutical and Biomaterial Approaches for Preventive and Restorative Dentistry

edited by Jan Kiryk and

Maciej Dobrzyński

submission deadline 25 Apr 2026 | Viewed by 140 | Submission Open

Keywords: dental prophylaxis; restorative dentistry; pharmaceuticals; biomaterials; dental innovations; dentistry of the future

(This special issue belongs to the Section Pharmacology)

Emerging Therapeutic Strategies for Heart Diseases

edited by Elias Rawish

submission deadline 25 Apr 2026 | Viewed by 136 | Submission Open

Keywords: medicinal chemistry; drug design; SAR; molecular modeling; pharmacophore; cardiovascular targets; inflammation; complement; neutrophils/NETosis; fibrosis; ion channels; SGLT2; GLP-1; biomarkers; binding affinity; PK/PD; ADME; radiopharmaceuticals; PET/SPECT; dosage form design; bioconjugates; prodrugs; nanoparticles; exosomes; siRNA/ASO/mRNA; peptides; antibodies; aptamers; targeted drug delivery; early clinical trials

(This special issue belongs to the Section Pharmacology)

Design and Development of PLGA and Polysaccharide Microparticles

edited by

Suzana Gonçalves Carvalho

and

Marlus Chorilli

submission deadline 25 Apr 2026 | Viewed by 129 | Submission Open

Keywords: drug delivery systems; polymeric systems; nanotechnology; controlled release

(This special issue belongs to the Section Medicinal Chemistry)

Natural Products with Anticancer Activity

edited by

Epole Ntungwe

submission deadline 25 Apr 2026 | Viewed by 127 | Submission Open

Keywords: natural products; extracts; anticancer activities; phytochemicals; molecular mechanisms

(This special issue belongs to the Section Medicinal Chemistry)

Application and Translational Research of Lanthanide/Nanomaterial-Conjugated Photosensitizers in Photodynamic Therapy

edited by

Céline Frochot

submission deadline 25 Apr 2026 | Viewed by 117 | Submission Open

Keywords: lanthanide-based nanomaterials; nanomaterial-conjugated photosensitizers; photodynamic therapy (PDT); targeted delivery; upconversion luminescence; preclinical evaluation; translational research; biocompatibility

(This special issue belongs to the Section Pharmaceutical Technology)

microRNAs and Perioperative Pharmacology

edited by

José Luis Guerrero-Orriach

and María Dolores Carmona-Luque

submission deadline 25 Apr 2026 | Viewed by 106 | Submission Open

Keywords: miRNAs; pharmacology; anesthetics; perioperative; biomarkers; breast cancer; ischemic heart disease; gene regulation; therapeutics; non-coding

(This special issue belongs to the Section Pharmacology)

Progress of Hydrogel Applications in Novel Drug Delivery Platforms, 2nd Edition

edited by

Anna Drabczyk

and

Katarzyna Bialik-Wąs

submission deadline 25 Apr 2026 | Viewed by 91 | Submission Open

Keywords: hydrogels; targeted drug delivery; drug release; drug delivery; smart hydrogels; stimuli-responsive hydrogels; controlled release; hydrogel-based drug delivery; drug carriers

(This special issue belongs to the Section Pharmaceutical Technology)

Natural Products and Bioactive Compounds for the Prevention and Treatment of Non-Communicable Chronic Diseases

edited by

Priscila de Souza

submission deadline 26 Apr 2026 | 3 articles | Viewed by 2178 | Submission Open

Keywords: natural products; phytochemicals; chronic diseases; functional foods; herbal medicine; non-communicable diseases; ethnopharmacology; bioactivity

(This special issue belongs to the Section Natural Products)

Plant-Derived Natural Compounds as Bioactive Molecules with Beneficial Effects on Human Health, 2nd Edition

edited by

Diego Morales

submission deadline 26 Apr 2026 | 2 articles | Viewed by 1394 | Submission Open

Keywords: plant bioactives; bioactive compounds; gut microbiome; immune-modulatory; antioxidant; hypocholesterolemic; antihypertensive; clinical trials

(This special issue belongs to the Section Natural Products)

New Perspectives in Ocular Pharmacology: 2nd Edition

edited by

Ioannis Tsinopoulos

and

Ioanna Mylona

submission deadline 26 Apr 2026 | Viewed by 62 | Submission Open

Keywords: ocular pharmacology; pharmacodynamics; ophthalmology; drug delivery systems

(This special issue belongs to the Section Pharmacology)

Natural Products and Their Modifications as Agents Used in the Fight Against Pathogens, 2nd Edition

edited by

Anna Duda-Madej

submission deadline 27 Apr 2026 | 1 articles | Viewed by 1804 | Submission Open

Keywords: plant extract; natural compounds; multidrug-resistant strains; intestinal microbiota; chemical modyfication; biotransformation

(This special issue belongs to the Section Natural Products)

Tumor Immunopharmacology, 2nd Edition

edited by

Marco A. Velasco-Velázquez

and

Nohemí Salinas-Jazmín

submission deadline 27 Apr 2026 | Viewed by 155 | Submission Open

Keywords: immunotherapy; immunomodulation; drug development; cytokine receptor antagonist; T-cell based therapies; therapeutic antibodies; drug delivery; cancer vaccine; immunoresistance; tumor-infiltrating lymphocytes (TILs); immune escape; immune checkpoint inhibitors; cytokine-based therapies; small molecule immunomodulators; combination therapy; precision oncology; tumor mutational burden (TMB); antibody-dependent cellular cytotoxicity (ADCC ); complement-dependent cytotoxicity (CDC); myeloid-derived suppressor cells (MDSCs)

(This special issue belongs to the Section Pharmacology)

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