Exosome and Biotherapeutic Strategies for Dermatological and Oncological Skin Complications
A special issue of Pharmaceuticals (ISSN 1424-8247). This special issue belongs to the section "Biopharmaceuticals".
Deadline for manuscript submissions: 25 December 2025 | Viewed by 141
Special Issue Editors
Interests: exosome-based therapies in aesthetic and regenerative medicine; plant-derived exosomes for skin repair and anti-inflammatory modulation; biotherapeutic strategies for scar treatment and wound healing; regenerative protocols for post-laser and post-procedural skin recovery; skin complications associated with oncologic therapies and their management; evidence-based integration of injectables, energy-based devices, and regenerative agents
Interests: advanced therapy medicinal products (ATMP); mesenchymal stem cells; keratinocytes; fibroblasts; chondrocytes; regenerative medicine; cell banking; burn treatment; chronic wound healing; autologous cell therapy
Special Issue Information
Dear Colleagues,
This Special Issue explores the expanding role of exosomes and biotherapeutic strategies in the treatment and regeneration of the skin across a wide spectrum of dermatologic conditions. As cell-free agents with regenerative, anti-inflammatory, and immunomodulatory properties, exosomes hold great promise for applications ranging from wound healing and scar remodeling to aesthetic skin rejuvenation and the management of inflammatory dermatoses. In recent years, their use has also gained attention in supporting skin recovery following energy-based procedures such as laser therapy.
Particular focus is also given to the role of exosomes in managing oncologic skin complications, including adverse cutaneous reactions caused by chemotherapy, radiotherapy, targeted therapies (e.g., EGFR and BRAF/MEK inhibitors), and immunotherapies. We invite original research articles, clinical case reports, and reviews that examine therapeutic mechanisms, safety, delivery strategies, and treatment outcomes. Interdisciplinary contributions from dermatology, oncology, and regenerative medicine are especially encouraged to foster integrated, patient-centered care models.
Keywords: Exosomes; dermatology; biotherapeutics; regenerative medicine; wound healing; aesthetic dermatology; skin complications; cancer therapy; laser-assisted recovery; translational skin therapy.
The scope of this Special Issue includes, but is not limited to:
- Exosome-based approaches for skin regeneration, rejuvenation, and scar modulation;
- Wound healing and post-procedural recovery (e.g., after laser or microneedling);
- Management of inflammatory skin diseases using exosomes;
- Treatment of oncologic skin complications caused by chemotherapy, radiotherapy, targeted therapies, and immunotherapy;
- Clinical studies and real-world case series;
- Advances in delivery systems and formulation of exosome-based therapeutics;
- Safety, regulatory, and standardization considerations in dermatologic applications;
- Interdisciplinary strategies bridging dermatology, oncology, and aesthetic medicine.
Dr. Lidia Majewska
Dr. Jacek M. Kijowski
Guest Editors
Manuscript Submission Information
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Keywords
- exosomes
- skin cancer
- dermatological therapy
- extracellular vesicles
- biotherapeutics
- regenerative medicine
- nanomedicine
- wound healing
- cancer-related skin manifestations
- dermatological drug delivery
- wound healing therapeutics
- cutaneous oncology
- exosome-based therapy
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