Metabolic Features and Nutritional Interventions in Chronic Diseases—2nd Edition
A special issue of Nutrients (ISSN 2072-6643). This special issue belongs to the section "Nutrition and Metabolism".
Deadline for manuscript submissions: 15 December 2025
Special Issue Editors
Interests: nutritional intervention; cardiovascular disease; atherosclerosis; vascular remodeling; aorta; aging; cell signaling; cell metabolism
Special Issues, Collections and Topics in MDPI journals
Interests: metabolic diseases; cancer; aging; molecular nutrition; mitochondrial metabolism; mitochondrial metal ions; mtDNA mutation/editing; ROS; ferroptosis
Special Issues, Collections and Topics in MDPI journals
Interests: iron metabolism; oxidative stress; intervention strategies
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Metabolic dysfunction is a hallmark feature of a spectrum of chronic diseases, comprising aging, cancer, and diseases affecting the cardiovascular system, digestive system, and endocrine system. The phenotypes associated with metabolic dysfunction vary depending on disease type and stage. In turn, altered metabolism drives disease progression and incidence. Nutritional interventions, utilizing bioactive compounds or tailored dietary regimens, have emerged as effective strategies to modulate metabolic dysfunctions, thereby mitigating disease progression and improving outcomes. For instance, tailored nutritional intervention in cancers with altered metabolism determines improved therapeutic responses. Additionally, counteracting muscle loss and osteoporosis are clinical goals that can provide nutritional support to an aging population. Mechanistically, nutritional interventions modulate metabolism through mitochondrial homeostasis, metabolic pathway reprogramming, immuno-regulation, and epigenome regulation to impact disease progression and outcome.
This Special Issue aims to provide an interdisciplinary platform covering the following topics:
- Characterizing metabolic features and/or nutritional requirements in certain types of chronic disease;
- Defining the effects and mechanism of a specific nutrient or nutritional intervention to target metabolism and disease;
- Developing new nutritional strategies that improve disease outcomes by altering metabolism.
We invite the submission of well-designed research articles, reviews, and meta-analyses addressing the above issues.
Dr. Yongting Luo
Dr. Junjie Luo
Dr. Peng An
Guest Editors
Dr. Yongting Luo
Dr. Junjie Luo
Dr. Peng An
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Nutrients is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- metabolic features
- metabolic reprogramming
- nutritional intervention
- bioactive nutrients
- dietary regimen
- chronic disease
- metabolic disease
- cardiovascular disease
- aging
- cancer
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