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Molecules publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Synthesis and Properties of Heterocyclic Compounds: Recent Advances—2nd Edition submission deadline 28 Feb 2026 | Viewed by 71 | Submission Open
Keywords: heterocyclic compounds; synthesis; applications; biological activity
(This special issue belongs to the Section Organic Chemistry)
Metal-Organic Framework-Derived Materials for High-Performance Ion Batteries
edited by and Wenting Li
submission deadline 28 Feb 2026 | Viewed by 65 | Submission Open
Keywords: metal– organic frameworks; MOF-derived materials; high-performance ion batteries; electrochemical performance; energy conversion; energy storage; nanoporous materials
(This special issue belongs to the Section Materials Chemistry)
Recent Advances in Green and Enzymatic Catalysis for Synthesis of Functional Molecules
edited by
submission deadline 28 Feb 2026 | Viewed by 62 | Submission Open
Keywords: green catalysis; enzymatic synthesis; sustainable chemistry; biocatalysis; functional molecules
(This special issue belongs to the Section Bioorganic Chemistry)
Natural Products Synthesis: From Carbohydrate Building Blocks to Bioactive Conjugates submission deadline 28 Feb 2026 | Viewed by 60 | Submission Open
Keywords: carbohydrate synthesis; glycosides; polysaccharides; synthetic chemistry; biological activities; glycomimetics; glycoderivatives
(This special issue belongs to the Section Natural Products Chemistry)
Health Promoting Compounds in Milk and Dairy Products, 2nd Edition
edited by and
submission deadline 28 Feb 2026 | Viewed by 57 | Submission Open
Keywords: milk; dairy products; functional compounds; food quality; protein and bioactive peptides; minerals; vitamins; antioxidant compounds; promoting health and well-being
(This special issue belongs to the Section Food Chemistry)
Biomass-Derived Chemicals and Materials for a Sustainable Environment
edited by Robson Rocha
submission deadline 28 Feb 2026 | Viewed by 56 | Submission Open
Keywords: biomass; bioenergy; bioprocesses; biomaterials; sustainable processes; solid waste to energy and new materials
(This special issue belongs to the Section Materials Chemistry)
Advanced Carbon Materials in Environment and Energy Storage submission deadline 28 Feb 2026 | Viewed by 43 | Submission Open
Keywords: graphene; carbon nanotubes; energy storage; environmental remediation; sustainable synthesis; hybrid carbon materials; solar energy and fuel cells
(This special issue belongs to the Section Materials Chemistry)
Environmental Pollutants and Oxidative Stress Chemistry
edited by and Gustavo Axel Elizalde-Velázquez
submission deadline 28 Feb 2026 | Viewed by 39 | Submission Open
Keywords: environmental pollutants; oxidative stress; reactive oxygen species (ROS); antioxidant defense; redox chemistry
(This special issue belongs to the Section Chemical Biology)
Advances in Photosynthesis and Electrosynthesis of Organic Compounds
edited by and Changsheng Wang
submission deadline 28 Feb 2026 | Viewed by 36 | Submission Open
Keywords: electrochemistry; electrosynthesis; continuous flow electrochemistry; process intensification; green synthesis
(This special issue belongs to the Section Cross-Field Chemistry)
Application of Chitosan and Hyaluronan submission deadline 1 Mar 2026 | 2 articles | Viewed by 2514 | Submission Open
Keywords: hyaluronan; chitosan; functionalized hyaluronan and chitosan; hyaluronan and chitosan derivatives; medicinal applications; polysaccharides; reactive oxygen species; tissue engineering; biodegradable; biological properties; medicine; cosmetics; food industry; water treatments
(This special issue belongs to the Section Applied Chemistry)
Organometallic Photochemistry: A Commemorative Special Issue Honoring Professor Alistair Lees submission deadline 1 Mar 2026 | Viewed by 208 | Submission Open
Keywords: photochemistry and photophysics; supramolecular photochemistry; excited state processes; photocatalysis; sensors and probes; photofunctional materials
(This special issue belongs to the Section Cross-Field Chemistry)
Gemini Surfactant Application Studies
edited by Iwona Kowalczyk and
submission deadline 1 Mar 2026 | Viewed by 134 | Submission Open
Keywords: gemini surfactants; biological activity; physicochemical analysis; smart material
(This special issue belongs to the Section Applied Chemistry)
New Approaches in the Synthesis of Organophosphorus Compounds
edited by and
submission deadline 10 Mar 2026 | Viewed by 158 | Submission Open
Keywords: organophosphorus chemistry; P-compounds; reactivity of P-compounds; P-C bond formation; phosphorus-based organocatalysis; phosphonium-based ionic liquids (PILs); mitochondria-targeted triphenylphosphonium-based compounds; bisphosphonates; neutralization of P-compounds; chemical warfare agents; structure elucidation of P-compounds
(This special issue belongs to the Section Organic Chemistry)
Bioactive Natural Products and Derivatives
edited by Xiaoxiao Huang and
submission deadline 15 Mar 2026 | 3 articles | Viewed by 1682 | Submission Open
Keywords: new natural product discovery; natural product derivatives; bioactivities and mechanisms of action of natural products; application; new methods and technologies
(This special issue belongs to the Section Bioorganic Chemistry)
N,O,S-Donor Ligands and Metal Complexes: From Structural Characterization to Biological and Catalytic Applications submission deadline 15 Mar 2026 | 1 articles | Viewed by 1197 | Submission Open
Keywords: N; O; S-donor ligands; metal complexes; catalysis; coordination chemistry; biomimetics; structural characterization; spectroscopy; DFT; theoretical modeling; biomedical applications; industrial processes
(This special issue belongs to the Section Applied Chemistry)
Magnetic Resonance in Food Analysis, 2nd Edition submission deadline 15 Mar 2026 | Viewed by 291 | Submission Open
Keywords: NMR spectroscopy; relaxometry; pulse sequences; molecular interactions; diffusion; imaging; foods
(This special issue belongs to the Section Food Chemistry)
Density Functional Theory (DFT): From Conceptual Developments to Practical Applications
edited by , , Manuel Treto-Suárez and
submission deadline 15 Mar 2026 | Viewed by 133 | Submission Open
Keywords: density functional theory (DFT) methods; Ab initio molecular dynamics; elucidation of detection mechanisms; electronic structure and binding energies; catalysis and photocatalysis; optical properties and excited-state dynamics; DFT benchmarking and perspectives; molecular descriptors based on density functional theory.
(This special issue belongs to the Section Computational and Theoretical Chemistry)
Supramolecular Strategies in Medicine and Environmental Science submission deadline 15 Mar 2026 | 1 articles | Viewed by 98 | Submission Open
Keywords: cyclodextrins; hyaluronic acid; therapeutic; drug delivery; supramolecular
(This special issue belongs to the Section Macromolecular Chemistry)
Applied Chemistry in Europe, 2nd Edition
edited by and Gianluca D'Abrosca
submission deadline 16 Mar 2026 | Viewed by 139 | Submission Open
Keywords: nano-materials; environmental chemistry; chemical synthesis; green chemistry; theoretical chemistry analytical methods
(This special issue belongs to the Section Applied Chemistry)
Exploring the Antioxidant Activity of Natural Extracts: New Findings and Potential Food- and Non-Food-Related Applications
edited by
submission deadline 26 Mar 2026 | Viewed by 644 | Submission Open
Keywords: natural antioxidants; superfruits; specialty crops; polyphenols; flavonoids; tannins; anthocyanins; carotenoids; vitamins; phytochemistry; extraction techniques; processing; functional food; sustainable technology; technical applications; antifouling; obesity; inflammation; diabetes; cosmetics; pharmaceuticals; environmental protection; material science; radical scavenging; nutraceuticals
(This special issue belongs to the Section Natural Products Chemistry)
Plant and Animal Bioreactors: Insights into Bioactive Molecules for Therapeutic Innovation submission deadline 30 Mar 2026 | 1 articles | Viewed by 1448 | Submission Open
Keywords: plant bioreactors; animal bioreactors; bioproduction; plant metabolites; plant hormones; biologics; biosimilars; drug research and development; nutraceuticals; plant engineering; pharmaceutical biotechnology; agricultural biotechnology; bioactive molecules
(This special issue belongs to the Section Natural Products Chemistry)
Stress-Related Biomarkers: Analytical Methods and Their Applications
edited by
submission deadline 30 Mar 2026 | 1 articles | Viewed by 1118 | Submission Open
Keywords: biomarkers; stress hormones; advanced glycation end-products; mental and physical stress; oxidative stress; glycation stress; Immunological stress; fatigue; aging; lifestyle-related diseases
(This special issue belongs to the Section Analytical Chemistry)
Edible and Biodegradable Films for Sustainable Food Packaging
edited by and Huimin Yong
submission deadline 30 Mar 2026 | Viewed by 155 | Submission Open
Keywords: sustainable food packaging; coating; film; natural polymers; characterization; structure; physicochemical property; functional property; application
(This special issue belongs to the Section Food Chemistry)
Flavor Scalping submission deadline 30 Mar 2026 | Viewed by 119 | Submission Open
Keywords: flavor compound absorption; plastic packaging materials; polyolefins; polyethyene terephthalate; product flavor loss; product sensory quality
(This special issue belongs to the Section Flavours and Fragrances)
Advances in the Synthesis of Natural Bioactive Compounds
edited by Honglei Liu
submission deadline 30 Mar 2026 | Viewed by 75 | Submission Open
Keywords: natural bioactive compounds; synthesis; biosynthesis
(This special issue belongs to the Section Natural Products Chemistry)
Novel Edible Proteins: Strategies for Improving Nutrient Bioavailability
edited by Yaqin Wang and Ndegwa Henry Maina
submission deadline 30 Mar 2026 | Viewed by 73 | Submission Open
Keywords: proteins; nutrient; bioavailability; protein modification; fermentation; chemistry; digestion; digestibility; anti-nutritional factors; health
(This special issue belongs to the Section Food Chemistry)
π-Conjugated Functional Molecules & Polymers submission deadline 31 Mar 2026 | 15 articles | Viewed by 32099 | Submission Open
Keywords: π -conjugated functional materials; conjugated porous polymers; covalent organic framework; metal– organic framework; synthetic methodology; aggregation-induced organic emissions; nonlinear optics; light-emitting diodes; organic field effect transistors; organic photovoltaic cells; photocatalysis
(This special issue belongs to the Section Materials Chemistry)
Bioactive Compounds: Applications and Benefits for Human Health
edited by Sara Baldelli, and
submission deadline 31 Mar 2026 | 6 articles | Viewed by 13095 | Submission Open
Keywords: bioactive compounds; polyphenols; terpenoids; alkaloids; glucosinolates; antioxidant; anti-inflammatory; cardiovascular diseases; bacterial and viral infections; microbiota; neurodegenerative diseases; cancer; sarcopenia; identification; purification; extraction; pre-clinical; clinical
(This special issue belongs to the Section Natural Products Chemistry)
Research Progress on Functional Lipids and Their Applications in Health Food Systems
edited by
submission deadline 31 Mar 2026 | 8 articles | Viewed by 10947 | Submission Open
Keywords: lipid crystallization; lipid oxidation; enzymatic lipid modification; processing; health benefits; structured emulsions; lipid emulsions; lipids capsules
(This special issue belongs to the Section Food Chemistry)
Green Chemistry Approaches to Analysis and Environmental Remediation
edited by
submission deadline 31 Mar 2026 | 9 articles | Viewed by 10013 | Submission Open
Keywords: chromatography; mass spectrometry; extraction; green analytical chemistry; emerging contaminants
(This special issue belongs to the Section Analytical Chemistry)
Recent Advances in Adsorbents for Environmental Pollution and Resource Recycling
edited by Wei Wang and Lang Yang
submission deadline 31 Mar 2026 | 5 articles | Viewed by 8642 | Submission Open
Keywords: adsorption; molecular structure design; environmental pollution; metal enrichment extraction; resource recycling; adsorbent preparation and synthesis; wastewater treatment
(This special issue belongs to the Section Green Chemistry)
Design, Synthesis and Applications of Novel Transition Metal Catalysts
edited by Hui Jiang and Junfang Gong
submission deadline 31 Mar 2026 | 5 articles | Viewed by 8024 | Submission Open
Keywords: pincer catalysts; transition metal catalysts; organic synthetic methodologies; photocatalysis; electrocatalysis; polymerization; fine chemistry
(This special issue belongs to the Section Applied Chemistry)
Review Papers in Analytical Chemistry, 2nd Edition
edited by
submission deadline 31 Mar 2026 | 4 articles | Viewed by 7800 | Submission Open
Keywords: analytical chemistry; analytical spectroscopy; environmental sciences; medical science; forensic science; cultural heritage; food analysis
(This special issue belongs to the Section Analytical Chemistry)
Organic Molecules in Drug Discovery and Development
edited by
submission deadline 31 Mar 2026 | 5 articles | Viewed by 7631 | Submission Open
Keywords: organic chemistry; chemical synthesis; chemical modifications; organic molecules; molecular mechanisms; bioactivity; drug development; drugs
(This special issue belongs to the Section Medicinal Chemistry)
In Silico Methods Applied in Drug and Pesticide Discovery, 3rd Edition submission deadline 31 Mar 2026 | 6 articles | Viewed by 7483 | Submission Open
Keywords: molecular modeling of small and complex molecules/macromolecules; homology modeling; molecular docking; virtual screening; ADME-Tox; ligand- and structure-based pharmacophore modeling; QSAR/QSPR models; drug/pesticide design; molecular dynamics
(This special issue belongs to the Section Computational and Theoretical Chemistry)
Hypervalent Iodine Chemistry: Promise and Prospects
edited by
submission deadline 31 Mar 2026 | 2 articles | Viewed by 7231 | Submission Open
Keywords: hypervalent compound; iodine; new reagent and catalyst; new synthetic transformation; synthetic application; the hypervalent iodine-bearing hybrid molecule
(This special issue belongs to the Section Organic Chemistry)
Chemistry of Nucleic Acids: From Structure to Biological Interactions
edited by and Federica D'Aria
submission deadline 31 Mar 2026 | 6 articles | Viewed by 6745 | Submission Open
Keywords: nucleic acid structures and function; modified nucleic acids; nucleic acid-targeting ligands; physicochemical studies of nucleic acids; thermodynamics and kinetics of nucleic acid structures; structure– function relationship of nucleic acids; nucleic acid– protein interactions; aptamers
(This special issue belongs to the Section Chemical Biology)
Advances in Functional Polymers and Their Applications
edited by and
submission deadline 31 Mar 2026 | 5 articles | Viewed by 6502 | Submission Open
Keywords: functional polymer; polymerization; post-polymerization modification; multi-component; hydrogel; 3D printing; biomaterials; polymer composite; surface and interface
(This special issue belongs to the Section Macromolecular Chemistry)
Novel Metabolism-Related Biomarkers in Cancer submission deadline 31 Mar 2026 | 4 articles | Viewed by 6359 | Submission Open
Keywords: cancer biomarkers; personalized medicine; metabolism; glucose; amino acid; glutamine; lipid; iron
(This special issue belongs to the Section Bioorganic Chemistry)
Synthetic Studies Aimed at Heterocyclic Organic Compounds, 2nd Edition
edited by
submission deadline 31 Mar 2026 | 7 articles | Viewed by 6270 | Submission Open
Keywords: heterocycles; synthesis; methods; medicinal; agricultural
(This special issue belongs to the Section Organic Chemistry)
Heterogeneous Catalysts: From Synthesis to Application
edited by Milan Kralik
submission deadline 31 Mar 2026 | 3 articles | Viewed by 4821 | Submission Open
Keywords: heterogeneous catalyst; acid– base; redox; enzymatic; electrocatalytic; photocatalytic; chemical specialties; characterization methods; mathematical modelling; process design; ecology; safety; economy
(This special issue belongs to the Section Organic Chemistry)
Multifunctional Natural Ingredients in Skin Protection and Care, 2nd Edition submission deadline 31 Mar 2026 | 3 articles | Viewed by 4197 | Submission Open
Keywords: plant extracts; natural compounds; biological activity; cosmetics; antioxidant; anti-aging; skin lightening; UV-protection
(This special issue belongs to the Section Natural Products Chemistry)
Recent Advances in the Toxicology and Safety of Medicinal Plants and Natural Products submission deadline 31 Mar 2026 | 3 articles | Viewed by 4179 | Submission Open
Keywords: toxicity of natural compounds and plant extracts; safety of natural products; drug development; in silico modeling; in vitro study; in vivo study
(This special issue belongs to the Section Natural Products Chemistry)
Extraction, Isolation, and Identification of Bioactive Compounds from Plants submission deadline 31 Mar 2026 | 4 articles | Viewed by 3917 | Submission Open
Keywords: natural products; extraction methods; isolation methods; chromatography; chemical characterization; bioactivity; antioxidant; antimicrobial; antiinflammation; bio-guided assay; biopesticides; biostimulants; nutraceuticals
(This special issue belongs to the Section Natural Products Chemistry)
Advances in the Application of Nanoparticles in Antimicrobial Research submission deadline 31 Mar 2026 | 2 articles | Viewed by 3898 | Submission Open
Keywords: nanoparticles; nanobiomaterials; antimicrobial activity; antimicrobial resistance; photodynamic antimicrobial therapy; innovation; drug delivery; sustainability
(This special issue belongs to the Section Nanochemistry)
Molecular Docking in Drug Discovery, 2nd Edition
edited by
submission deadline 31 Mar 2026 | 3 articles | Viewed by 3831 | Submission Open
Keywords: computer aided drug design; drug discovery; molecular docking; structure– activity relationships; drug design
(This special issue belongs to the Section Medicinal Chemistry)
Exclusive Papers of Editorial Board Members and Invited Scholars in “Materials Chemistry”, 2nd Edition
edited by
submission deadline 31 Mar 2026 | 4 articles | Viewed by 3749 | Submission Open
Keywords: biomaterials; nanomaterials; hybrid materials; core-shell materials; thin films; self-assembling systems; hydrogels; sensors and biosensors
(This special issue belongs to the Section Materials Chemistry)
Porous Carbons for CO2 Adsorption and Capture
edited by and Jinsong Shi
submission deadline 31 Mar 2026 | 4 articles | Viewed by 3272 | Submission Open
Keywords: porous carbons; carbon nanotubes; graphene oxide; carbon nanomaterials; activated carbons; adsorbents; CO2 adsorption; CO2 capture; physisorption; chemical activation; physical activation; surface functionalization; pore structure design; carbon doping; nitrogen doping; CO2 capture efficiency; CO2 selectivity; direct air capture (DAC); CO2 storage; industrial CO2 capture; carbon capture and utilization (CCU); CO2 adsorption mechanisms; adsorption kinetics; sustainable materials; adsorbent regeneration; machine learning in material design
(This special issue belongs to the Section Materials Chemistry)
Chromatography—The Ultimate Analytical Tool, 3rd Edition submission deadline 31 Mar 2026 | 3 articles | Viewed by 3031 | Submission Open
Keywords: chromatography; high-performance liquid chromatography; ultra-high-performance liquid chromatography; gas chromatography; two-dimensional gas chromatography; two-dimensional liquid chromatography; paper chromatography; liquid chromatography; preparative chromatography; supercritical fluid chromatography; thin-layer chromatography
(This special issue belongs to the Section Analytical Chemistry)
Recent Experimental and Theoretical Advances of Corrosion Protection
edited by , Miguel Castro, Guillermo E. Negrón-Silva and
submission deadline 31 Mar 2026 | 2 articles | Viewed by 2947 | Submission Open
Keywords: electrochemical techniques; synthesis of corrosion inhibitors; molecular dynamics; quantum theoretical modelling; coatings
(This special issue belongs to the Section Electrochemistry)
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