Molecular Editing Through Skeletal Transformations
A special issue of Molecules (ISSN 1420-3049). This special issue belongs to the section "Organic Chemistry".
Deadline for manuscript submissions: 31 October 2026 | Viewed by 103
Special Issue Editor
Interests: organic synthesis; heterocyclic chemistry; C-H activation; cyclization; michael addition; photochemistry
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Skeletal transformations have emerged as powerful tools for rapidly accessing new regions of chemical space by directly modifying complex molecular frameworks, often bypassing the need for de novo synthesis. Unlike traditional synthetic strategies that rely on stepwise construction or late-stage functionalization, skeletal editing allows chemists to rearrange, insert, delete, or exchange atoms within existing molecular scaffolds in a site- or chemo-specific manner. This Special Issue, “Molecular Editing Through Skeletal Transformations”, will showcase cutting-edge research in this dynamic field. Emphasis will be placed on original articles, perspectives, and communications that focus on the development of new reactions, catalytic strategies, and mechanistic insights, including both experimental and computational approaches. We look forward to receiving your contributions, which will highlight the potential of skeletal transformations across drug discovery, natural product synthesis, materials science, and sustainable chemistry, while illustrating how molecular editing could redefine modern chemical synthesis and inspire future innovations.
Dr. Gianfranco Favi
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Molecules is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- skeletal editing
- rearrangement
- transmutation
- ring expansion/contraction
- atom swapping
- atom deletion/insertion
- unimolecular fragment coupling
- peripheral editing
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