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Molecules publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Chemical Modifications and Interactions of Food Macromolecules: Mechanisms and Impacts on Quality
edited by Ling Liu and Yixiao Shen
submission deadline 28 Feb 2026 | 1 articles | Viewed by 470 | Submission Open
Keywords: lipid; protein; molecular interactions; food safety; food stability
(This special issue belongs to the Section Food Chemistry)
Natural Dyes for the Textile and Leather Industries—for the Future’s Sustainability submission deadline 28 Feb 2026 | Viewed by 442 | Submission Open
Keywords: natural dyes; textile and leather industries; extraction methodologies; pigment characterization; new dye to fiber binding agents and strategies; bioactive properties; industrial applications
(This special issue belongs to the Section Colorants)
Visible Light Active Photocatalysts for Organic Synthesis
edited by Wentao Xu
submission deadline 28 Feb 2026 | Viewed by 359 | Submission Open
Keywords: organic chemistry; photocatalyst; synthesis; radical; single-electron transfer; atom transfer; energy transfer
(This special issue belongs to the Section Organic Chemistry)
Recent Advances in Fluorescent Probes: Design, Synthesis, Properties and Application
edited by Zhaoyang Wang and Yancheng Wu
submission deadline 28 Feb 2026 | Viewed by 335 | Submission Open
Keywords: fluorescent probes; fluorescent sensors; fluorescent analytical technology; chemical detection; biological detection; fluorescence
(This special issue belongs to the Section Photochemistry)
Research Advances in Li-Ion Battery Materials: Present and Future
edited by
submission deadline 28 Feb 2026 | Viewed by 308 | Submission Open
Keywords: lithium-ion battery; anode materials; cathode materials; characterization
(This special issue belongs to the Section Applied Chemistry)
Advances in Radiation Detection Materials and Technology
edited by Qianli Li and Weiguang Yang
submission deadline 28 Feb 2026 | Viewed by 248 | Submission Open
Keywords: radiation-sensitive material; scintillation material; luminescent center optimization; radiation detection materials; flexible dosimeter; semiconductor heterostructure engineering; synthesis; characterization; application; determination of the crystal structure of biomacromolecules
Hierarchical Organization in Polymeric and Amphiphilic Self-Assembly
edited by Thi Vo
submission deadline 28 Feb 2026 | Viewed by 246 | Submission Open
Keywords: self-assembly; amphiphile; polymers; computational modeling; synthesis; material design
(This special issue belongs to the Section Macromolecular Chemistry)
Anti-Cancer and Anti-Inflammatory Activity of Medicinal Plants
edited by
submission deadline 28 Feb 2026 | Viewed by 243 | Submission Open
Keywords: medicinal plants; anti-cancer activity; anti-inflammatory activity; natural products; modification; derivatives; bioassay
(This special issue belongs to the Section Medicinal Chemistry)
Computational Chemistry in Homogeneous and Heterogeneous Catalysis and Surface Chemistry
edited by Haya Kornweitz and
submission deadline 28 Feb 2026 | Viewed by 231 | Submission Open
Keywords: density functional theory (DFT); heterogeneous catalysis; homogeneous catalysis; surface reactions; reaction mechanism; metallic Surfaces; nanoparticles; adsorption; desorption; ab initio calculations; material science; surface modelling; reaction kinetics; thermochemistry and reactivity; transition State theory; potential energy surfaces (PES); hydrogenation; hydrogen evolution reaction (HER); oxygen evolution reaction (OER); CO2 reduction; electrocatalysis; machine learning
Heterocyclic Bioactive Molecules: Structural Analysis and Innovative Applications in Medicinal Chemistry submission deadline 28 Feb 2026 | Viewed by 231 | Submission Open
Keywords: heterocyclic compounds; drug design; AI machine learning; bioorthogonal chemistry; molecular imaging; small-molecule probes; PROTAC
(This special issue belongs to the Section Medicinal Chemistry)
Secondary Metabolites: Green Isolation, AI-Assisted Elucidation, and Mechanistic Insight
edited by Niko Radulović and
submission deadline 28 Feb 2026 | Viewed by 229 | Submission Open
Keywords: secondary metabolites; natural products; AI/ML dereplication; metabolomics; advanced NMR/MS; green/flow isolation; chemoproteomics; mechanism of action; FAIR data
(This special issue belongs to the Section Natural Products Chemistry)
Chemistry of Amino Acids, Peptides, and Proteins
edited by and Nicholas Truex
submission deadline 28 Feb 2026 | Viewed by 208 | Submission Open
Keywords: amino acids; peptides; proteins; synthesis; derivatives; characterization; structural studies; biophysical properties; natural products
(This special issue belongs to the Section Macromolecular Chemistry)
Harnessing Peptides and Peptidomimetics in Modern Drug Discovery
edited by
submission deadline 28 Feb 2026 | Viewed by 194 | Submission Open
Keywords: peptide synthesis; peptidomimetics; cyclic peptides; peptide therapeutics; peptide drug discovery; modified peptides; bioactive peptides
(This special issue belongs to the Section Medicinal Chemistry)
Chemical Biology in Europe submission deadline 28 Feb 2026 | Viewed by 193 | Submission Open
Keywords: chemical probes; bioorthogonal chemistry; chemical proteomics; target identification; probe-based visualization; PTM detection
(This special issue belongs to the Section Chemical Biology)
Design, Synthesis and Applications of Fluorescent Probes
edited by and
submission deadline 28 Feb 2026 | Viewed by 192 | Submission Open
Keywords: fluorescent probes; bioimaging; design synthesis; molecular imaging; cell biology; disease mechanisms; diagnostic imaging; drug discovery; biocompatibility
(This special issue belongs to the Section Medicinal Chemistry)
Theme Issue in Honor to Prof. Dr. Douglas Stephan’ Great Achievement in Inorganic Chemistry
edited by Meera Mehta and Andrew Jupp
submission deadline 28 Feb 2026 | Viewed by 189 | Submission Open
Keywords: inorganic chemistry; catalysis; complexes
Synthesis and Characterization of Functional Materials for Electrochemical Energy Storage and Conversion—2nd Edition
edited by Feifei Wang
submission deadline 28 Feb 2026 | Viewed by 189 | Submission Open
Keywords: energy storage and conversion; electrochemical systems; batteries; hydrogen; supercapacitors; CO2 conversion
Complexes as Tool for Design and Synthesis of Species with Biological Application
edited by
submission deadline 28 Feb 2026 | Viewed by 187 | Submission Open
Keywords: metal complex; resistance; biofilm; antitumor; carrier; target biomolecule; drug design; hybrid material
(This special issue belongs to the Section Medicinal Chemistry)
Recent Advances in Radical Chemistry
edited by and Ying Cheng
submission deadline 28 Feb 2026 | Viewed by 184 | Submission Open
Keywords: radical chemistry; radical cross-coupling; photocatalysis; electrochemical synthesis; transition metal catalysis
(This special issue belongs to the Section Organic Chemistry)
Fluorescent Sensing in Food and Environmental Detection submission deadline 28 Feb 2026 | Viewed by 180 | Submission Open
Keywords: environmental pollutants; food contaminants; organic residues; heavy metals; fluorescent sensing; fluorescent materials; food analysis; food quality; pollutant monitoring; food safety
(This special issue belongs to the Section Analytical Chemistry)
Current Topics and Applications of Chiral Auxiliaries
edited by Shawn Raynard Hitchcock
submission deadline 28 Feb 2026 | Viewed by 177 | Submission Open
Keywords: chiral auxiliary; asymmetric synthesis; diastereoselection; organic synthesis; stereochemistry; chiral control
(This special issue belongs to the Section Organic Chemistry)
Metal Ions and Metal Complexes in Medicinal Chemistry submission deadline 28 Feb 2026 | 1 articles | Viewed by 175 | Submission Open
Keywords: metal ions; metal complexes; synthesis; study; spectral analysis; biological activity; ligands
(This special issue belongs to the Section Medicinal Chemistry)
Green Organic Synthesis: Innovations for a Sustainable Future
edited by
submission deadline 28 Feb 2026 | Viewed by 170 | Submission Open
Keywords: sustainability; organic synthesis; green chemistry; precise synthesis; chemoselectivity; regioselectivity; enantioselectivity; catalysis
(This special issue belongs to the Section Organic Chemistry)
Bioactive Molecules for Targeted Cancer Therapy
edited by and Robert A. Falconer
submission deadline 28 Feb 2026 | Viewed by 167 | Submission Open
Keywords: enzymatic inhibitors; fragment-based discovery; chemical biology; covalent ligands; payloads; prodrug; (poly)peptide conjugates; antibody– drug conjugates; computational chemistry
(This special issue belongs to the Section Medicinal Chemistry)
Synthesis of Natural Compounds and Derivatives
edited by Fanie van Heerden and Mamoalosi Selepe
submission deadline 28 Feb 2026 | Viewed by 154 | Submission Open
Keywords: natural compounds; synthesis; total synthesis; semi-synthesis; derivatives
(This special issue belongs to the Section Natural Products Chemistry)
Nitrogen Containing Heterocyclic Scaffolds: Synthesis and Bioactivity
edited by and
submission deadline 28 Feb 2026 | Viewed by 151 | Submission Open
Keywords: heterocycles; heteroaromatics; drug discovery; organic synthesis; structure-activity relationship
(This special issue belongs to the Section Medicinal Chemistry)
Photocatalytic Water Splitting: Cutting-Edge Research and Future Directions
edited by
submission deadline 28 Feb 2026 | Viewed by 148 | Submission Open
Keywords: photocatalytic water splitting; hydrogen production; photocatalysts; heterojunctions; co-catalysts; charge carrier
(This special issue belongs to the Section Photochemistry)
Chemical Analyses and Applications of Essential Oils—2nd Edition
edited by
submission deadline 28 Feb 2026 | Viewed by 147 | Submission Open
Keywords: essential oils; bioactive compounds; liquid phase; vapor phase; potential applications
(This special issue belongs to the Section Natural Products Chemistry)
Green Conversion of Polymeric and Textile Waste into Functional Materials submission deadline 28 Feb 2026 | Viewed by 140 | Submission Open
Keywords: green chemistry; polymer conversion; textile waste valorization; plastic management; resource recovery; recycling; upcycling; functional materials
(This special issue belongs to the Section Green Chemistry)
Biodegradable Polymers in Biological Application submission deadline 28 Feb 2026 | Viewed by 134 | Submission Open
Keywords: natural polymers; synthetic polymers; controlled degradation; compositional and structural modifications; processing
(This special issue belongs to the Section Macromolecular Chemistry)
Advanced Nanostructured Materials for Electrochemical Energy Storage Devices
edited by and
submission deadline 28 Feb 2026 | Viewed by 125 | Submission Open
Keywords: electrochemical energy storage; supercapacitors; batteries; flow batteries; 2D transition metal carbides/nitride (MXene) nanomaterials; transition metal compounds; aqueous batteries; advanced nanostructured materials
(This special issue belongs to the Section Materials Chemistry)
Advancements on Field Detection Based on Nucleic Acid Amplification
edited by Xiong Xiong, and
submission deadline 28 Feb 2026 | Viewed by 125 | Submission Open
Keywords: nucleic acid; isothermal amplification; visual detection; colorimetric detection; fluorescence-based detection; point-of-care test; field detection
(This special issue belongs to the Section Analytical Chemistry)
Heterocyclic Compounds and Their Metal Complexes as Potential Anticancer Drugs submission deadline 28 Feb 2026 | Viewed by 118 | Submission Open
Keywords: heterocyclic metal complexes; in vitro activity; anticancer activity; cell cycle; apoptosis; 3D cell culture
(This special issue belongs to the Section Medicinal Chemistry)
Organometallic Compounds: Synthesis and Catalysis submission deadline 28 Feb 2026 | Viewed by 115 | Submission Open
Keywords: organometallic compounds; synthesis; catalysis; chemistry; structure
(This special issue belongs to the Section Organometallic Chemistry)
Recent Advances in Functionalized Nanomaterials: Design, Synthesis, Characterization, and Application—2nd Edition
edited by
submission deadline 28 Feb 2026 | Viewed by 115 | Submission Open
Keywords: functionalized nanomaterials; functionalized strategies; compositions; nanostructures; energy storage; sensing; environmental remediation; catalytic
(This special issue belongs to the Section Nanochemistry)
Emerging Trends in Two-Dimensional Materials: Synthesis, Properties and Applications
edited by Xiao Zhi
submission deadline 28 Feb 2026 | Viewed by 110 | Submission Open
Keywords: two-dimensional materials; biosensors; graphene; energy storage; catalysis; electronic conductivity
(This special issue belongs to the Section Materials Chemistry)
Synthesis and Properties of Heterocyclic Compounds: Recent Advances—2nd Edition submission deadline 28 Feb 2026 | Viewed by 104 | Submission Open
Keywords: heterocyclic compounds; synthesis; applications; biological activity
(This special issue belongs to the Section Organic Chemistry)
Advanced Electrocatalysts: Design, Characterization, and Applications in Sustainable Conversion Reactions
edited by Bruno Manzolli Rodrigues
submission deadline 28 Feb 2026 | Viewed by 102 | Submission Open
Keywords: electrocatalysis; nanostructured catalysts; atomically dispersed catalysis; sustainable catalysis; oxygen reduction reaction (ORR); oxygen evolution reaction (OER); CO2 reduction reaction (CO2RR); biomass conversion
(This special issue belongs to the Section Electrochemistry)
Metal-Organic Framework-Derived Materials for High-Performance Ion Batteries
edited by and Wenting Li
submission deadline 28 Feb 2026 | Viewed by 101 | Submission Open
Keywords: metal– organic frameworks; MOF-derived materials; high-performance ion batteries; electrochemical performance; energy conversion; energy storage; nanoporous materials
(This special issue belongs to the Section Materials Chemistry)
Recent Advances in Green and Enzymatic Catalysis for Synthesis of Functional Molecules
edited by
submission deadline 28 Feb 2026 | Viewed by 95 | Submission Open
Keywords: green catalysis; enzymatic synthesis; sustainable chemistry; biocatalysis; functional molecules
(This special issue belongs to the Section Bioorganic Chemistry)
Health Promoting Compounds in Milk and Dairy Products, 2nd Edition
edited by and
submission deadline 28 Feb 2026 | Viewed by 94 | Submission Open
Keywords: milk; dairy products; functional compounds; food quality; protein and bioactive peptides; minerals; vitamins; antioxidant compounds; promoting health and well-being
(This special issue belongs to the Section Food Chemistry)
Theoretical, Computational and Experimental Advances on Molecular Optical Properties, 2nd Edition submission deadline 28 Feb 2026 | Viewed by 93 | Submission Open
Keywords: synthesis; theoretical computation; photophysical characterization; structure– propertyies relationship; bio-application; imaging
(This special issue belongs to the Section Physical Chemistry)
Natural Products Synthesis: From Carbohydrate Building Blocks to Bioactive Conjugates submission deadline 28 Feb 2026 | Viewed by 85 | Submission Open
Keywords: carbohydrate synthesis; glycosides; polysaccharides; synthetic chemistry; biological activities; glycomimetics; glycoderivatives
(This special issue belongs to the Section Natural Products Chemistry)
Biomass-Derived Chemicals and Materials for a Sustainable Environment
edited by Robson Rocha
submission deadline 28 Feb 2026 | Viewed by 72 | Submission Open
Keywords: biomass; bioenergy; bioprocesses; biomaterials; sustainable processes; solid waste to energy and new materials
(This special issue belongs to the Section Materials Chemistry)
Environmental Pollutants and Oxidative Stress Chemistry
edited by and Gustavo Axel Elizalde-Velázquez
submission deadline 28 Feb 2026 | Viewed by 60 | Submission Open
Keywords: environmental pollutants; oxidative stress; reactive oxygen species (ROS); antioxidant defense; redox chemistry
(This special issue belongs to the Section Chemical Biology)
Advanced Carbon Materials in Environment and Energy Storage submission deadline 28 Feb 2026 | Viewed by 59 | Submission Open
Keywords: graphene; carbon nanotubes; energy storage; environmental remediation; sustainable synthesis; hybrid carbon materials; solar energy and fuel cells
(This special issue belongs to the Section Materials Chemistry)
Advances in Photosynthesis and Electrosynthesis of Organic Compounds
edited by and Changsheng Wang
submission deadline 28 Feb 2026 | Viewed by 54 | Submission Open
Keywords: electrochemistry; electrosynthesis; continuous flow electrochemistry; process intensification; green synthesis
(This special issue belongs to the Section Cross-Field Chemistry)
Application of Chitosan and Hyaluronan submission deadline 1 Mar 2026 | 2 articles | Viewed by 3559 | Submission Open
Keywords: hyaluronan; chitosan; functionalized hyaluronan and chitosan; hyaluronan and chitosan derivatives; medicinal applications; polysaccharides; reactive oxygen species; tissue engineering; biodegradable; biological properties; medicine; cosmetics; food industry; water treatments
(This special issue belongs to the Section Applied Chemistry)
Gemini Surfactant Application Studies
edited by Iwona Kowalczyk and
submission deadline 1 Mar 2026 | 1 articles | Viewed by 359 | Submission Open
Keywords: gemini surfactants; biological activity; physicochemical analysis; smart material
(This special issue belongs to the Section Applied Chemistry)
Organometallic Photochemistry: A Commemorative Special Issue Honoring Professor Alistair Lees submission deadline 1 Mar 2026 | Viewed by 233 | Submission Open
Keywords: photochemistry and photophysics; supramolecular photochemistry; excited state processes; photocatalysis; sensors and probes; photofunctional materials
(This special issue belongs to the Section Cross-Field Chemistry)
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