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Molecules publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Chemical Transformations and Analysis in Food: Nutrition, Flavor Compounds, and Microbiological Research submission deadline 30 Jun 2026 | Viewed by 14 | Submission Open
Keywords: flavor compounds; fermented food; flavor formation; flavor compound production/synthesis
(This special issue belongs to the Section Food Chemistry)
Synthesis and Application of Porphyrin-Based Catalysts
edited by
submission deadline 30 Jun 2026 | Viewed by 13 | Submission Open
Keywords: porphyrin synthesis; catalysis; renewable energy; photocatalysis; electrocatalysis; homogeneous catalysis
(This special issue belongs to the Section Applied Chemistry)
Lipid Oxidation and Flavor in Foods submission deadline 30 Jun 2026 | Viewed by 13 | Submission Open
Keywords: lipid oxidation; food flavor; bioactive compounds in food
(This special issue belongs to the Section Food Chemistry)
Applications of Porous Organic Frameworks in Environmental Remediation
edited by , Xingjie Wang and Kaikai Ma
submission deadline 30 Jun 2026 | Viewed by 12 | Submission Open
Keywords: porous organic frameworks (POFs); covalent organic frameworks (COFs); porous aromatic frameworks (PAFs); hydrogen-bonded organic frameworks (HOFs); environmental remediation; pollutant adsorption; catalytic degradation; gas capture and conversion; functional porous materials
(This special issue belongs to the Section Applied Chemistry)
Charge Dynamics and Stability Engineering in Next-Generation Quantum Dots
edited by
submission deadline 30 Jun 2026 | Viewed by 12 | Submission Open
Keywords: quantum dots; nanoparticles; surface chemistry; structure– property relations; stability
(This special issue belongs to the Section Physical Chemistry)
Overcoming Drug Resistance in Cancer: Molecular Mechanisms and Innovative Strategies
edited by
submission deadline 30 Jun 2026 | Viewed by 10 | Submission Open
Keywords: cancer therapeutics; epigenetic regulation; adaptive signaling pathways; tumor microenvironment; cancer targeted therapy resistance; biomarkers
(This special issue belongs to the Section Medicinal Chemistry)
Molecular Design and Synthesis of Novel Energetic Compounds, 2nd Edition
edited by
submission deadline 30 Jun 2026 | Viewed by 10 | Submission Open
Keywords: energetic compounds; molecular design; synthesis; structure; performance; sensitivity
Insight into Organic Semiconductor Materials
edited by Runfeng Chen and Chao Zheng
submission deadline 30 Jun 2026 | Viewed by 9 | Submission Open
Keywords: organic semiconductors; organic photonics; inorganic/organic hybrid materials; excitons; electroluminescence; photovoltaics; vacuum/solution process; energy transfer
(This special issue belongs to the Section Materials Chemistry)
Recent Advances in Supramolecular Photochemistry
edited by
submission deadline 30 Jun 2026 | Viewed by 9 | Submission Open
Keywords: supramolecular photochemistry; supramolecular bioimaging; photoactive supramolecular assemblies; photocatalysis; aggregation-induced emission (AIE); energy and electron transfer; confined-space photochemistry; photoresponsive materials
(This special issue belongs to the Section Photochemistry)
Advances in the Chemical Analysis of Prehistoric Materials
edited by
submission deadline 30 Jun 2026 | Viewed by 8 | Submission Open
Keywords: archaeological tools (resins; adhesives); chromatography (gas chromatography); infrared spectroscopy; nuclear magnetic resonance (NMR); archaeobotany; archaeology; terpenoids; sesquiterpenes; volatile organic compounds (VOCs)
(This special issue belongs to the Section Analytical Chemistry)
Advanced Optoelectronic Functional Materials: From Fundamental Innovation to Cutting-Edge Applications
edited by Fuquan Bai
submission deadline 30 Jun 2026 | Viewed by 4 | Submission Open
Keywords: design; synthesis; characterization; application; theoretical; optoelectronic functional material; perovskite solar cell; 2D material; graphene; TMDs; heterostructure; photodetector; flexible electronics; sensor; quantum dot; LED
(This special issue belongs to the Section Materials Chemistry)
Supramolecular Gels: Structure-Property Correlation and Their Applications in Sensors and Environmental Remediation submission deadline 30 Jun 2026 | Viewed by 3 | Submission Open
Keywords: design; structure– property correlation; dye removal; water remediation; sensors
(This special issue belongs to the Section Materials Chemistry)
Chemical and Functional Characterization of Novel Plant Proteins
edited by
submission deadline 30 Jun 2026 | Submission Open
Keywords: novel plant proteins; chemical characterization; functional properties; protein structure– function relationships; extraction and modification techniques; techno-functional behavior; protein digestibility and bioactivity; sustainable protein sources
(This special issue belongs to the Section Food Chemistry)
Alternative Routes for the Delivery of Drug Molecules
edited by , and Teodora Popova
submission deadline 1 Jul 2026 | Viewed by 164 | Submission Open
Keywords: transdermal; nasal; pulmonary; ophthalmic; liposomes; dendrimers; microneedles; cubosomes
(This special issue belongs to the Section Medicinal Chemistry)
Natural Product Leads Targeting Inflammatory Pathways submission deadline 1 Jul 2026 | Viewed by 54 | Submission Open
Keywords: natural products; lead compounds; anti-inflammatory; inflammatory pathways; drug discovery; medicinal plants; phytochemistry
(This special issue belongs to the Section Natural Products Chemistry)
Synthesis and Application of Heteroatomic Containing Compounds submission deadline 1 Jul 2026 | Viewed by 37 | Submission Open
Keywords: organometallic syntheses; heteroatomic asymmetry center; P-stereogenic center; asymmetric syntheses; enantioselective syntheses; transition metal complexes
(This special issue belongs to the Section Applied Chemistry)
Design and Application of Functional Supramolecular Materials
edited by
submission deadline 9 Jul 2026 | 1 articles | Viewed by 900 | Submission Open
Keywords: supramolecular chemistry; noncovalent interactions; self-assembly; host– guest chemistry; functional materials
(This special issue belongs to the Section Materials Chemistry)
Nanomaterial-Based Biosensors: From Design to Analytical Applications
edited by Irene Ojeda and Diana Vilela-Garcia
submission deadline 15 Jul 2026 | Viewed by 32 | Submission Open
Keywords: nanomaterial-based biosensors; nanomaterials; electrochemical biosensors; nanocomposites; analytical chemistry; electrode modification; nanostructures; sensor interfaces; electroanalysis; biofunctionalization
(This special issue belongs to the Section Nanochemistry)
Novel Analytical Techniques in Food Chemistry
edited by
submission deadline 15 Jul 2026 | Viewed by 14 | Submission Open
Keywords: food quality and safety; food authenticity; food analysis; mass spectrometry; spectroscopic techniques; biosensors; chemometrics and machine learning; foodomics
(This special issue belongs to the Section Analytical Chemistry)
The Design and Synthesis of Nanomaterials for Electrochemical Energy Storage and Conversion
edited by Yan Zhou and Zhen Wu
submission deadline 16 Jul 2026 | Viewed by 24 | Submission Open
Keywords: electrochemical energy storage; electrochemical energy conversion; batteries; supercapacitors; nanostructured electrode materials; nanostructured electrocatalysts
(This special issue belongs to the Section Applied Chemistry)
Chemistry, Bioactivity and Authenticity of Sugar-Rich and Fermented Foods and Beverages submission deadline 20 Jul 2026 | Viewed by 60 | Submission Open
Keywords: sugar-rich foods; fermented beverages; chemical characterization; analytical techniques; bioactive compounds; metabolomics; authenticity; food control
(This special issue belongs to the Section Food Chemistry)
Nanomaterials for Biomedicine: Innovations and Challenges
edited by and
submission deadline 30 Jul 2026 | 2 articles | Viewed by 2214 | Submission Open
Keywords: nanomaterial; targeted drug delivery; bio-imaging; antimicrobial application; cancer immunotherapy; nanovaccine
(This special issue belongs to the Section Nanochemistry)
Advanced Materials for Energy Applications: From Fuels to Batteries and Beyond, 2nd Edition
edited by
submission deadline 30 Jul 2026 | 1 articles | Viewed by 387 | Submission Open
Keywords: hydrogen storage materials; CO2 capture; natural gas sweetening; fossil fuel recovery
(This special issue belongs to the Section Materials Chemistry)
Small-Molecule Inhibitors as Anticancer Drugs submission deadline 30 Jul 2026 | Viewed by 168 | Submission Open
Keywords: small-molecule apoptosis-protein-family inhibitors; small-molecule mitotic inhibitors; small-molecule kinase inhibitors; small-molecule receptor tyrosine kinase inhibitors; small-molecule non-receptor tyrosine kinase inhibitors; small-molecule serine/threonine kinase inhibitors; small-molecule epigenetic inhibitors; small-molecule proteasome inhibitors; small-molecule inhibitors for disrupting protein– protein interactions; small-molecule inhibitors aimed at exploiting tumor metabolic vulnerabilities
(This special issue belongs to the Section Medicinal Chemistry)
Plant Bioactives in Human Health: From Phytochemistry to Molecular Mechanisms submission deadline 30 Jul 2026 | Viewed by 57 | Submission Open
Keywords: bioactive compounds; bioavailability; extraction methods; biological activities; cell signalling; functional applications; nutraceuticals; human metabolism; toxicity; bioactive-gut microbiota relationships
(This special issue belongs to the Section Natural Products Chemistry)
Research Progress and Application of Natural Compounds—2nd Edition submission deadline 31 Jul 2026 | 6 articles | Viewed by 11663 | Submission Open
Keywords: natural products; primary and secondary metabolites; bioactive compounds; bioactive peptides; anticancer natural products; flavonoids; drug design
(This special issue belongs to the Section Natural Products Chemistry)
Photocatalytic Materials and Photocatalytic Reactions, 2nd Edition
edited by and
submission deadline 31 Jul 2026 | 8 articles | Viewed by 9818 | Submission Open
Keywords: photocatalysts; carbon neutral; charge carrier separation; photocatalytic mechanism; photoredox reaction; nanocomposites
(This special issue belongs to the Section Photochemistry)
30th Anniversary of Molecules—Recent Advances in Applied Chemistry submission deadline 31 Jul 2026 | 7 articles | Viewed by 9784 | Submission Open
Keywords: applied chemistry; new molecules and natural materials; analytical methods and techniques; electrochemistry and energy; biodegradable materials and medicines; environment and green chemistry; theoretical chemistry
(This special issue belongs to the Section Applied Chemistry)
Lignin: New Insights in Chemistry
edited by
submission deadline 31 Jul 2026 | 1 articles | Viewed by 3979 | Submission Open
Keywords: lignin valorization; catalytic depolymerization; enzymatic lignin transformation; thermochemical processes; lignin-derived fine chemicals; synthetic biology in lignin research; circular bioeconomy
(This special issue belongs to the Section Green Chemistry)
Synthesis, Identification and Biological Evaluation of Novel Natural and Derivative Products
edited by
submission deadline 31 Jul 2026 | 1 articles | Viewed by 3202 | Submission Open
Keywords: organic synthesis; natural products; theoretical calculation; DFT; structure identification; biological evaluation
(This special issue belongs to the Section Natural Products Chemistry)
Molecular Insights into Functional Lipids in Food Chemistry
edited by and Siyu Zhang
submission deadline 31 Jul 2026 | 2 articles | Viewed by 2986 | Submission Open
Keywords: structured lipid; synthesis; crystallization; fatty acid; glyceride  
(This special issue belongs to the Section Food Chemistry)
Advances in Nanomaterials for Biomedical Applications, 2nd Edition
edited by Xueen Jia and Ce Zhang
submission deadline 31 Jul 2026 | 1 articles | Viewed by 2820 | Submission Open
Keywords: 2D nanomaterials; metal– organic frameworks (MOFs); metasurfaces; biosensor; drug delivery
(This special issue belongs to the Section Nanochemistry)
30th Anniversary of Molecules—Recent Advances in Food Chemistry
edited by and Marta Coelho
submission deadline 31 Jul 2026 | 2 articles | Viewed by 2776 | Submission Open
Keywords: functional foods; nutraceuticals; bioactive compounds; analytical techniques; by-products; food chemistry
(This special issue belongs to the Section Food Chemistry)
Extraction Techniques for Sample Preparation submission deadline 31 Jul 2026 | 2 articles | Viewed by 2197 | Submission Open
Keywords: sorbent-based extraction; liquid-based extraction; supercritical- or subcritical-based extraction; HPLC determination; GC determination; LC-MS-based analysis; chemical fingerprinting
(This special issue belongs to the Section Analytical Chemistry)
Unveiling the Applications of Bioactive Compounds in Functional Foods for Optimal Human Health—2nd Edition
edited by and
submission deadline 31 Jul 2026 | 1 articles | Viewed by 1634 | Submission Open
Keywords: functional foods; bioactive ingredients; health benefits; immune function; gut health; disease prevention
(This special issue belongs to the Section Food Chemistry)
Biological Activity of Metal Complexes: Design and Characterization Strategies submission deadline 31 Jul 2026 | 1 articles | Viewed by 1562 | Submission Open
Keywords: metal complexes; biological activity; metallodrugs; anticancer: antibacterial; antiviral; antiparasitic: delivery methods; biophysical characterization; DFT; docking
(This special issue belongs to the Section Inorganic Chemistry)
Terpenes and Their Derivatives: From Nature to Medical Applications submission deadline 31 Jul 2026 | 2 articles | Viewed by 1551 | Submission Open
Keywords: terpenes; plants; animals; microbes; extraction technologies; structure elucidation; chemical synthesis and biosynthesis; biological investigation
(This special issue belongs to the Section Natural Products Chemistry)
Design and Preparation of New Metal Catalysts for Functional Organic Compounds Synthesis
edited by
submission deadline 31 Jul 2026 | 1 articles | Viewed by 1381 | Submission Open
Keywords: transition metal complexes; hybrid catalysts; nanocatalysts; single-atom catalysts; sustainable organic synthesis; natural products
(This special issue belongs to the Section Organometallic Chemistry)
Anti-Inflammatory and Antimicrobial Compounds and Extracts from Plant Sources
edited by and
submission deadline 31 Jul 2026 | 1 articles | Viewed by 1034 | Submission Open
Keywords: phytochemicals; anti-inflammatory; antimicrobial; plants; extracts; botanicals; metabolites; functional foods
(This special issue belongs to the Section Natural Products Chemistry)
Extraction, Chromatography, and Mass Spectrometry Analysis of Food and Plant Biomolecules submission deadline 31 Jul 2026 | 1 articles | Viewed by 956 | Submission Open
Keywords: liquid chromatography; gas chromatography; sample preparation; extraction; supercritical fluid extraction; solid-phase extraction; liquid– liquid extraction
(This special issue belongs to the Section Analytical Chemistry)
Indole Derivatives: Synthesis and Application 3rd edition submission deadline 31 Jul 2026 | 1 articles | Viewed by 793 | Submission Open
Keywords: organic synthesis; natural products; heterocyclic compounds; ring cyclisations; metal complexes; organometallic compounds; polymers; molecular rearrangements; biological activity
Kinetic and Mechanistic Studies on Multifunctional Antioxidants submission deadline 31 Jul 2026 | Viewed by 244 | Submission Open
Keywords: thermodynamic; kinetic; quantum chemistry; reaction paths; oxidative stress; protective effect; ROS inhibition; reactivity
(This special issue belongs to the Section Computational and Theoretical Chemistry)
Advances in Sustainable and Functional Bio-Based Porous Materials for Environmental Remediation
edited by and Yufei Nan
submission deadline 31 Jul 2026 | Viewed by 166 | Submission Open
Keywords: bio-based materials; porous structure; adsorption of heavy metals/organics/dyes/microplastics; sustainable processing
(This special issue belongs to the Section Materials Chemistry)
Synthesis and Application of Nanomaterials for Bio-Based and Environmental Pollution Molecules Detection and Purification
edited by and Gina M. Chiarella
submission deadline 31 Jul 2026 | Viewed by 156 | Submission Open
Keywords: nano-enabled environmental cleanup; sustainable nanotechnology; toxic ion sequestration; environmental remediation; nano compound synthesis; green; eco-friendly nanomaterials as catalysis; water; food; and soil safety
(This special issue belongs to the Section Nanochemistry)
Chemical and Physical Interactions Between Food and Packaging: Safety, Stability, and Quality submission deadline 31 Jul 2026 | Viewed by 153 | Submission Open
Keywords: packaging; coating; physical properites; chemical properties; food quality; food safety
(This special issue belongs to the Section Food Chemistry)
Discovery and Structure Optimization of Antibacterial Natural Products
edited by
submission deadline 31 Jul 2026 | Viewed by 153 | Submission Open
Keywords: natural products; structure optimization; antibiotic discovery; antibacterial activity; scaffold diversity
(This special issue belongs to the Section Natural Products Chemistry)
Synthesis and Biological Properties of Natural Product Analogues
edited by and
submission deadline 31 Jul 2026 | Viewed by 131 | Submission Open
Keywords: natural product analogues; synthesis; biological evaluation; structure– activity relationship (SAR); NP-based therapeutic agents; pharmacophores
(This special issue belongs to the Section Natural Products Chemistry)
Biocatalysis in Deep Eutectic Solvents: Stability, Immobilization and Applications submission deadline 31 Jul 2026 | Viewed by 118 | Submission Open
Keywords: biocatalysis; deep eutectic solvents; enzyme stability; enzyme selectivity; enzyme immobilization; reaction medium; enzymatic reactors; enzyme molecular dynamics
(This special issue belongs to the Section Green Chemistry)
Recent Advances in Chemical Treatments of Wastewater
edited by and
submission deadline 31 Jul 2026 | Viewed by 104 | Submission Open
Keywords: wastewater treatment processes; purification mechanism; environmental remediation materials; water reuse
(This special issue belongs to the Section Green Chemistry)
Essential Oils in Human Health—2nd Edition submission deadline 31 Jul 2026 | Viewed by 103 | Submission Open
Keywords: essential oils; extraction; characterization; composition; biological properties
(This special issue belongs to the Section Natural Products Chemistry)
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