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Nanomaterial-Based Biosensors: From Design to Analytical Applications

A special issue of Molecules (ISSN 1420-3049). This special issue belongs to the section "Nanochemistry".

Deadline for manuscript submissions: 30 June 2027 | Viewed by 772

Editors


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Guest Editor
Faculty of Pharmaceutical Sciences, Complutense University of Madrid, 28040 Madrid, Spain
Interests: enzymes; aptamers, antibodies, nanomaterials; nanosensors; biosensors; electrochemistry

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Guest Editor
Nanosensors and Nanomachines Group, Department of Analytical Chemistry, Faculty of Chemistry, Complutense University of Madrid, 28040 Madrid, Spain
Interests: electrochemistry; nanomaterials; nanosensors; biosensors; nano- and micromotors; Janus materials; microfluidics

Special Issue Information

Dear Colleagues,

Nanomaterial-based biosensors have emerged as powerful analytical tools thanks to the integration of nanotechnology into biosensing platforms. The use of nanomaterials, including metal and metal oxide nanoparticles, carbon nanostructures, quantum dots, and nanocomposites, has greatly enhanced the sensitivity, selectivity, and stability of biosensors. These nanostructures offer a large surface area, enhanced conductivity, and tunable physicochemical properties that facilitate the efficient immobilization of biomolecules and promote signal amplification, making them highly suitable for a wide range of analytical applications.

This Special Issue, “Nanomaterial-Based Biosensors: From Design to Analytical Applications,” aims to gather recent advances in the synthesis and functionalization of nanomaterials, the design of nanostructured sensing interfaces, and their implementation in analytical devices. Particular attention will be given to electrochemical biosensors, where nanomaterials play a key role in enhancing electron transfer and detection performance. Both original research articles and comprehensive reviews are welcome.

This collection aims to offer an updated perspective on how nanostructured materials and nanoscale interfaces are influencing the development of the next generation of analytical biosensors, thereby contributing to more sensitive, reliable, and sustainable detection systems across biomedical, environmental, and industrial fields.

Dr. Irene Ojeda
Dr. Diana Vilela-Garcia
Guest Editors

Manuscript Submission Information

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Keywords

  • nanomaterial-based biosensors
  • nanomaterials
  • electrochemical biosensors
  • nanocomposites
  • analytical chemistry
  • electrode modification
  • nanostructures
  • sensor interfaces
  • electroanalysis
  • biofunctionalization

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Published Papers (1 paper)

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Research

15 pages, 1389 KB  
Article
Electrocatalytic Mn2Mo3O8/MnO-Carbon Nanocomposite Electrodes for Hydrogen Peroxide and Glucose Sensing
by Foroozan Samimi, Jorge Urraca, Anabel Villalonga, Esther García-Díez, Alfredo Sánchez, Irene Ojeda, Masoud Salavati-Niasari and Reynaldo Villalonga
Molecules 2026, 31(13), 2205; https://doi.org/10.3390/molecules31132205 - 23 Jun 2026
Viewed by 516
Abstract
Metal oxide nanomaterials tailored at the nanoscale are opening new avenues for advanced electroanalytical sensing devices with enhanced properties, including improved electrocatalytic activity. In this work, a novel Mn2Mo3O8/MnO-MWCNT nanocomposite was employed to modify a screen-printed carbon [...] Read more.
Metal oxide nanomaterials tailored at the nanoscale are opening new avenues for advanced electroanalytical sensing devices with enhanced properties, including improved electrocatalytic activity. In this work, a novel Mn2Mo3O8/MnO-MWCNT nanocomposite was employed to modify a screen-printed carbon electrode, enabling the fabrication of an amperometric sensor for H2O2 operating at relatively low applied potential due to the catalytic activity of the nanocomposite. Further functionalization of this nanostructured surface with glucose oxidase allowed the construction of an electrochemical glucose biosensor, where the Mn2Mo3O8/MnO-MWCNT material acted as an efficient electrocatalyst for hydrogen peroxide detection. The H2O2 sensor exhibited a linear response from 0.06 mM to 3.00 mM, with a sensitivity of (2.22 ± 0.02) µA mM−1 and a detection limit of 22 µM. The glucose biosensor showed a linear response in the range from 0.10 mM to 18.9 mM glucose, with a sensitivity of (0.345 ± 0.005) µA mM−1, and a detection limit of 29 µM. The biosensor displayed excellent selectivity and high stability and was successfully applied to the determination of glucose in lactose-free skimmed milk. Full article
(This article belongs to the Special Issue Nanomaterial-Based Biosensors: From Design to Analytical Applications)
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