Special Issue "Repositioning Natural Products in Drug Discovery"
Deadline for manuscript submissions: 31 August 2021.
Interests: computer-aided drug design; medicinal chemistry; drug discovery
Interests: medicinal plants; natural bioactive compounds; phytochemical analysis; natural products chemistry
Special Issues and Collections in MDPI journals
We invite you to contribute to this Special Issue of Molecules entitled “Repositioning Natural Products in Drug Discovery”. Drug repurposing has become one of the most popular and successful strategies to reduce the failures typically associated with drug discovery. Drug repurposing involves the identification of novel targets and different therapeutic uses of drugs and drug candidates under development. As such, preclinical development and optimization issues, such as adverse toxicology profiles, can be prevented. Although most drug repurposing success stories derive from serendipity, research efforts are currently directed toward predicting new repurposing possibilities on rational grounds. Remarkably, while most drug repurposing studies rely on synthetic compounds, significant opportunities from natural products are expected to come into play. Natural products are characterized by unique and favorable properties, great structural diversity, and the provision of valuable chemical entities for drug discovery campaigns.
This Special Issue will focus on experimental and computational approaches in the research area of natural products and repurposing, including studies on, but not limited to, the identification of new targets of natural compounds, the discovery of bioactive natural and semi-synthetic compounds, their isolation and characterization, dereplication of natural extracts, analysis of structure–activity relationships of natural products, and in silico screening.
Prof. Giulio Rastelli
Prof. Federica Pellati
Dr. Luca Pinzi
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Molecules is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2000 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.