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Special Issue "Advances in One-pot Reaction"

A special issue of Molecules (ISSN 1420-3049). This special issue belongs to the section "Organic Chemistry".

Deadline for manuscript submissions: 31 January 2020

Special Issue Editor

Guest Editor
Prof. Romano V. A. Orru

Department of Chemistry and Pharmaceutical Sciences, VU University Amsterdam, De Boelelaan 1083, 1081 HV Amsterdam, The Netherlands
Website | E-Mail
Phone: 0031205987447
Interests: synthetic methodology; multi component reactions; biocatalysis; natural products

Special Issue Information

Dear Colleagues,

One-pot cascade reactions (processes comprising several consecutive reactions) allow scientists to carry out chemical syntheses to completion in fewer steps than conventional techniques. Generally, they improve the eco-friendliness and time-cost efficiency associated with the synthesis of drugs and other high-value organic molecules. Therefore, these one-pot processes have the potential to reduce our environmental impact, and lower the overall costs associated with producing life-saving medicines. Developing more efficient techniques for synthesising complex drug molecules like for example heterocycles or peptide mimics is a painstaking process. Working towards higher efficiency and yield in the synthesis of pharmaceutical drugs using one-pot reactions in order to improve accessibility to life-saving medicines is at the heart of this Special Issue of Molecules

Prof. Romano V. A. Orru
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Molecules is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1800 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • One-pot processes
  • Green chemistry
  • Cascade reactions
  • Biocatalysis
  • Atom- and Step efficiency
  • Organic Synthesis

Published Papers

This special issue is now open for submission.
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