Recent Advances in Antitubercular Drug Discovery

Dear Colleagues,

Tuberculosis (TB) is still the leading cause of death from a single infectious disease agent, with an estimated 1.7 billion people infected with Mycobacterium tuberculosis, and more than 10 million new cases each year. The current anti-TB therapy has reduced the mortality, but it requires a long treatment period, and can have serious adverse reactions. Moreover, multidrug-resistant (MDR) and extensively drug-resistant (XDR) M. tuberculosis strains have now spread worldwide and become a global issue. For these reasons novel TB drugs and novel drug targets are needed; indeed, considerable efforts, involving different approaches and expertise, have been made in the last years.

The aim of this Special Issue is, therefore, to collect research papers, short communications, and critical review articles, that are focused on the discovery and development of novel antitubercular drugs, new potential biological targets, and therapeutic approaches.

Dr. Laurent Chiarelli
Guest Editor

Manuscript Submission Information

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