Special Issue "Natural Products and Drug Discovery"
Deadline for manuscript submissions: 15 June 2019
Prof. Dr. Pinarosa Avato
Dipartimento di Farmacia-Scienze del Farmaco, Università degli Studi di Bari Aldo Moro Via Orabona 4, 70125 Bari, Italy
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Interests: phytochemicals; natural products; plant biodiversity; medicinal plants; food plants; bioactivity; polyphenols; glucosinolates; biocides
Natural products hold a prominent position in the discovery and development of many drugs used nowadays, with diverse indications for human and animal health. Especially, plants have played a leading role as a source of specialized metabolites with medical effects; other organisms such as marine and terrestrial animals and microorganisms produce very important drug candidate molecules. Specialized metabolites from all these natural sources can be used directly as bioactive compounds, or as drug precursors. Due to their wide chemical diversity they can act as drug prototypes and/or be used as pharmacological tools for different targets. Some examples of natural metabolites which have been developed into useful medical drugs are the cardiotonic digoxin from Digitalis sp., the antimalarial artemisinin from Artemisia annua, the anti-cancer taxol, from Taxus sp., or the podophyllotoxin from Podophyllum peltatum, which served as synthetic model for the anti-cancer etoposide. The study of natural products is still attracting a great scientific attention and their current importance as valuable leads for drug discovery is undebatable. I cordially invite authors to contribute original articles, as well as survey articles, that will give the readers of Molecules updated and new perspective about natural products in drug discovery including, but not limited to natural sources, identification and separation of bioactive phytochemicals, standardization, new biological targets, pre-clinical and clinical trials, pharmacological effects/side effects, and bioassays.
Prof. Dr. Pinarosa Avato
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Molecules is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1800 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- natural products
- drug discovery
- biocidal compounds
- human and animal health
- natural sources