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Special Issue "Mass Spectroscopy in Chemical Biology"

A special issue of Molecules (ISSN 1420-3049). This special issue belongs to the section "Chemical Biology".

Deadline for manuscript submissions: 31 January 2019

Special Issue Editor

Guest Editor
Prof. Dr. Mark Brönstrup

Helmholtz Centre for Infection Research (HZI), Inhoffenstraße 7, 38124 Braunschweig, Germany
Leibniz University Hannover, Schneiderberg 38, 30167 Hannover, Germany
Website | E-Mail
Interests: antibiotics; antivirals; drug discovery; mass spectrometry; infectious diseases; metabolomics; lead discovery

Special Issue Information

Dear Collegues,

Mass spectrometry has been a major contributor to the advancement of all life science disciplines in the past two decades. This is particularly true for the young discipline of ‘chemical biology’, dedicated to deciphering cell biology with small molecule probes, and to translate those insights to novel therapeutic innovations. Mass spectrometry is a core technology to map molecular interactions in the cell, e.g., to elucidating the cellular targets of small molecules in chemoproteomic experiments, to map protein-protein interaction networks, to detect supramolecular complexes in their native state, or to capture enzymatic activity. Furthermore, quantitiative mass spectrometry is perfectly suited to capture global effects of external or internal stimuli on the cell in proteomics, primary and secondary metabolomics or lipidomics studies—with high temporal and spacial resolution. In this Special Issue, we would like to give an overview on the tremendous versatility and power of mass spectrometry to advance chemical biology. We seek for research studies reporting methodological advances, as well as applications of mass spectrometry, to solve chemical and biological problems.

Prof. Dr. Mark Mark Brönstrup
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Molecules is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1800 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • mass spectrometry
  • chemical biology
  • chemoproteomics
  • metabolomics
  • natural products
  • target identification
  • drug discovery
  • assay development
  • mode-of-action

Published Papers

This special issue is now open for submission.
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