Diterpene and Its Significance in Natural Medicine

Dear Colleagues,

Diterpenes have been studied for nearly 200 years, since the investigation of resin acid’s chemical structure in 1824. Now, they form one of the largest families of natural molecules. According to the Dictionary of Natural Products 2016 (web version), a total of 18,450 diterpenoids, sharing 126 types of skeletons, have been reported.

Bearing diverse linear and cyclic carbon skeletones, diterpenoids have been demonstrated to have a broad spectrum of bioactivities, such as anti-bacterial, anti-inflammatory, anti-viral, anti-tumor, cytotoxic, insecticidal, and immunomodulating effects. Some of them have been developed as new drugs, e.g., taxol in cancer therapy.

Along with advances in analytical instruments, synthesis methods, and biotransformation studies, more and more new diterpenoids are revealed and attract increasing interest of scientists in multiple disciplines. As Guest Editors, we cordially invite researchers to submit their work relevant to these topics to this Special Issue of Molecules.

Dr. Quan-Bin Han
Dr. Jian-Xin Pu
Guest Editors

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