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Design and Applications of Novel Chemical Sensors for Environmental and Biological Relevance

A special issue of Molecules (ISSN 1420-3049). This special issue belongs to the section "Cross-Field Chemistry".

Deadline for manuscript submissions: closed (1 April 2025) | Viewed by 2775

Special Issue Editor


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Guest Editor
1. School of Life and Environmental Sciences, Guangxi Key Laboratory of Information Materials, Guilin University of Electronic Technology, Guilin 541004, China
2. College of Chemistry, Guangdong University of Petrochemical Technology, Guandu Road, Maoming 525000, China
Interests: biosensor; nano materials; nanozyme; biomarker; fluorescence sensing; electrochemical sensing

Special Issue Information

Dear Colleagues,

Chemical sensors are widely used for the detection and assessment of environmental and biological relevance. This Special Issue will host discussions of the design, development, and application of environmental chemical sensors and biosensors in order to determine environmental and biological relevance. The application of technologies for use in new nano-structured composite materials and their micro-fabrication and micro-chips will play a leading role in the development of such sensors. We welcome articles addressing the rational assembly of dynamic macromolecules, biocomponent stability, DNA-based biosensors, molecular beacons, electronic nose, multianalyte transducers, sensor systems and others technologies as tools for environmental monitoring.

Prof. Dr. Guiyin Li
Guest Editor

Manuscript Submission Information

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Keywords

  • chemical sensor
  • nano-structured composite materials
  • heavy metal ions
  • pathogenic bacteria
  • environmental estrogens
  • biological relevance
  • biomarker

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Published Papers (3 papers)

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Research

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13 pages, 1946 KiB  
Article
Invisible but Insidious Effects of Microplastics
by Natalia A. Stefanova, Yulia S. Sotnikova, Aleksandra E. Osechkova, Elena V. Karpova, Dmitriy N. Polovyanenko, Anzhella Zh. Fursova, Daria A. Kiseleva, Tatyana G. Tolstikova, Nataliya G. Kolosova and Elena G. Bagryanskaya
Molecules 2024, 29(23), 5776; https://doi.org/10.3390/molecules29235776 - 6 Dec 2024
Viewed by 1078
Abstract
Increasing evidence on the adverse health impacts of microplastics (MPs) is available, but their associated risks to the well-being of humans and long-term impacts are poorly understood. An indicator of the remote effects of MPs may be their influence on the rate of [...] Read more.
Increasing evidence on the adverse health impacts of microplastics (MPs) is available, but their associated risks to the well-being of humans and long-term impacts are poorly understood. An indicator of the remote effects of MPs may be their influence on the rate of aging. To assess the effects of MPs on the aging process, we used accelerated senescence OXYS rats that develop a complex of geriatric diseases. We prepared the polyethylene terephthalate MPs (2–6 microns in size) and in OXYS and Wistar (maternal strain) rats assessed the influence of chronic administration of MPs (10 or 100 mg/kg per day from age 1.5 to 3.5 months,) on the hematological and biochemical blood parameters, spatial learning, and memory. In addition, the effects of MPs on the development of cataracts and retinopathy, similar to age-related macular degeneration (AMD), in OXYS rats were assessed. We found that in the absence of significant changes in standard clinical blood parameters, chronic MP administration negatively affected the cognitive functions of both Wistar rats and OXYS rats. Additionally, a dose of 100 mg/kg MPs contributed to cataract and AMD progression in OXYS rats. Our results suggest that MPs may increase the rate of aging and, in the long term, lifespan. Full article
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Review

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31 pages, 11565 KiB  
Review
Detection of Selected Heavy Metal Ions Using Organic Chromofluorescent Chemosensors
by Samina Aslam, Iram Kousar, Sadia Rani, Wajiha Altaf, Sadia Bristy and Rachid Skouta
Molecules 2025, 30(7), 1450; https://doi.org/10.3390/molecules30071450 - 25 Mar 2025
Viewed by 540
Abstract
Heavy and transition metal (HTM) ions have significant harmful effects on the physical environment and play crucial roles in biological systems; hence, it is crucial to accurately identify and quantify any trace pollution. Molecular sensors which are based on organic molecules employed as [...] Read more.
Heavy and transition metal (HTM) ions have significant harmful effects on the physical environment and play crucial roles in biological systems; hence, it is crucial to accurately identify and quantify any trace pollution. Molecular sensors which are based on organic molecules employed as optical probes play a crucial role in sensing and detecting toxic metal ions in water, food, air, and biological environments. When appropriate combinations of conduction and selective recognition are combined, fluorescent and colorimetric chemosensors are appealing instruments that enable the selective, sensitive, affordable, portable, and real-time investigation of the possible presence of heavy and transition metal ions. This feature article aims to provide readers with a more thorough understanding of the different methods of synthesis and how they work. As noted in the literature, we will highlight colorimetric and fluorometric sensors based on their receptors into multiple categories for heavy metal ion detection, such as Hg2+, Ag2+, Cd2+, Pb2+, and In3+, and simultaneous multiple-ion detection. Full article
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36 pages, 13020 KiB  
Review
Modern Approaches in Organic Chromofluorescent Sensor Synthesis for the Detection of Considered First-Row Transition Metal Ions
by Samina Aslam, Iram Kousar, Sadia Rani, Isra Zainab, Sadia Bristy and Rachid Skouta
Molecules 2025, 30(6), 1263; https://doi.org/10.3390/molecules30061263 - 12 Mar 2025
Cited by 1 | Viewed by 635
Abstract
The development of optical chemosensors for the sensitive and selective detection of trace-level metal ions in aqueous solutions has drawn a lot of attention from the scientific community in recent years. Organic sensors offer a number of advantages over traditional identification techniques, including [...] Read more.
The development of optical chemosensors for the sensitive and selective detection of trace-level metal ions in aqueous solutions has drawn a lot of attention from the scientific community in recent years. Organic sensors offer a number of advantages over traditional identification techniques, including low cost, high sensitivity, selectivity, and simplicity of synthesis. We will focus on colorimetric and fluorometric sensors based on their receptors for the real-time detection of certain first-row transition metal ions like Cr3+, Mn2+, Fe2+, Co2+, Ni2+ Cu2+, and Zn2+. The development of these sensors will aid in the rapid and simple resolution of several problems linked to the detection of potentially hazardous metal ions at trace levels in diverse biological and environmental components. This review article not only gives a comprehensive understanding of the existing techniques, but also encourages more research efforts to address the evolving demands in the field of trace transition metal ion detection. Full article
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