Special Issue "Transcription Factors as Therapeutic Targets"
Deadline for manuscript submissions: closed (31 October 2018).
2. Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore
Interests: transcription; transcription factor; enhancer; core regulatory circuit; stem cells; hematopoiesis; acute leukemia; T-cell acute lymphoblastic leukemia; oncogene; TAL1
Special Issues, Collections and Topics in MDPI journals
Deregulation of transcription factor genes are frequently observed in various human diseases, such as cancer. Understanding the molecular pathogenesis, as well as the development of therapeutic approaches, are crucial to further advance the treatment outcome. Although the feasibility of transcription factors as therapeutic targets has long been realized, the development of drugs is still very challenging due to several pharmacological and biological reasons. Therefore, an improved knowledge is necessary to make transcription factors “actionable”. This Special Issue aims to provide a forum for the dissemination of the latest information on new approaches and methods targeting transcription factors, and with methods of testing their success in cancer or other human diseases.
Dr. Takaomi Sanda
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