Synthesis and Identification of Small Compounds Active in Neurodegeneration, Part II

Dear Colleagues,

Considering the success of the first Special Issue, it is our great pleasure to announce pleasure the second edition of “Synthesis and Identification of Small Compounds Active in Neurodegeneration, Part II”.

Keeping in mind the social impact of neurodegenerative diseases and the difficulty of identifying a single effective therapy, interest in creating scientific networks as a possibility for discovering new chemical entities remains active.

Due the high versatility of small molecules in terms of physiochemical properties, easier availability, various administration routes, and defined chemical structures, they play a central role in medicinal chemistry and represent promising drug candidates. Natural sources and chemical synthesis are two options for developing novel neuroprotective drug candidates. In particular, the rational combination of two or more chemical entities or synthetic modification of a common skeleton make them a favorable tool in rational design.

The main aim of this Special Issue is to collect and illustrate the latest developments in the field of the isolation, structural characterization, rational design, synthesis, and biological evaluation of compounds with low molecular weight related to neurodegenerative diseases.

We invite all researchers working in this field to contribute original articles and reviews covering the main aspects of the topic. We hope that this Special Issue will continue to provide a forum for thought-provoking ideas.

Dr. Barbara De Filippis
Prof. Dr. Gunter Peter Eckert
Guest Editors

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