Interaction Between Biomacromolecules and Dietary Antioxidants—Characterisation and Physiological Significance
A special issue of Molecules (ISSN 1420-3049). This special issue belongs to the section "Chemical Biology".
Deadline for manuscript submissions: 31 March 2026 | Viewed by 2
Special Issue Editors
Interests: metabolism; IGF; glycome; protein–ligand interaction; oxidative stress; nutraceuticals
Interests: phycobiliproteins; protein–ligand interactions; protein immobilization; chemical modifications of proteins; hydrogels
Special Issue Information
Dear Colleagues,
Dietary antioxidants are naturally occurring compounds, predominantly of plant origin, that augment the body’s intrinsic antioxidant defense mechanisms. In recent decades, their biological activities beyond their site of origin have gained significant attention, leading to their application as dietary supplements in disease prevention and, in some instances, as therapeutic agents. A common characteristic of these compounds is their complex ADMET (absorption, distribution, metabolism, excretion, and toxicity) profile. This complexity arises from their interactions with components of the matrix from which they are derived, and proteins within the human body. Previous studies have demonstrated that such interactions can influence the beneficial properties of dietary antioxidants by altering their structure and bioavailability.
Consequently, a deeper understanding of the molecular interactions between dietary antioxidants and biomacromolecules is essential for enhancing their stability, bioavailability, and targeted delivery. This Special Issue aims to compile a comprehensive overview of current research on the interaction between dietary antioxidants and biomacromolecules, whether they originate from the food matrix or are endogenous to the human body, employing in vitro and in silico approaches. We invite researchers to submit original research articles or reviews that advance the understanding of antioxidant–biomacromolecule interactions and their implications for health-promoting applications.
Dr. Miloš Šunderić
Dr. Nikola Gligorijević
Dr. Olgica Nedic
Guest Editors
Manuscript Submission Information
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Keywords
- protein–ligand interaction
- food matrix
- dietary antioxidants
- spectroscopic methods
- molecular docking
- cell culture
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