Advances in QuEChERS-Based Methodologies for Multiresidue Analysis
A special issue of Molecules (ISSN 1420-3049). This special issue belongs to the section "Analytical Chemistry".
Deadline for manuscript submissions: 31 March 2026 | Viewed by 41
Special Issue Editors
Interests: functional ingredients; agri-food by-product valorization
Special Issues, Collections and Topics in MDPI journals
Interests: food safety; foodborne contaminants; QuEChERS
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Originally developed for the analysis of pesticide residues in food, the QuEChERS (Quick, Easy, Cheap, Effective, Rugged, and Safe) methodology has evolved into a widely adopted approach for multiresidue analysis in complex matrices. Its adaptability, simplicity, and cost-efficiency have established it as a cornerstone in the field of sample preparation, enabling reliable detection of chemical contaminants, including pesticides, biocides, veterinary drugs, and persistent organic pollutants.
Current research continues to refine and expand QuEChERS-based methods, integrating novel sorbents, improved clean-up strategies, and innovative solvent systems to enhance sensitivity, selectivity, and matrix compatibility.
Furthermore, its seamless integration with advanced analytical techniques such as LC-MS/MS and GC-MS/MS has opened new avenues for comprehensive, high-throughput monitoring of contaminants in food, environmental, agricultural, and biological samples.
This Special Issue aims to highlight the latest developments in QuEChERS-based methodologies, focusing on analytical performance, matrix versatility, method validation, and practical implementation.
We especially welcome contributions addressing the following topics:
- Optimization and modification of QuEChERS protocols;
- Application to emerging contaminants and complex matrices;
- Integration with advanced detection systems (e.g., LC-MS/MS, GC-MS/MS);
- Comparative studies between QuEChERS and alternative extraction methods;
- Validation, standardization, and regulatory aspects;
- Green chemistry approaches and miniaturization strategies.
This Special Issue provides a timely platform for researchers and practitioners to share innovations that reinforce the value of QuEChERS in modern analytical science. Both original research articles and review papers are invited.
We look forward to your contributions.
Dr. Mikel Añibarro-Ortega
Dr. José Pinela
Guest Editors
Adrián Conde-Díaz, PhD Student
Guest Editor Assistant
Email: acondedi@ull.edu.es
Departamento de Química, Facultad de Ciencias, Universidad de La Laguna, Avda. Fco. Sánchez, s/n, 38200 Santa Cruz de Tenerife, Spain
Interests: plasticizers; trace contami-nants; QuEChERS
Manuscript Submission Information
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Keywords
- QuEChERS methodology
- multiresidue analysis
- sample preparation
- emerging contaminants
- LC-MS/MS and GC-MS/MS
- method validation and standardization
- green chemistry approaches
- complex matrices
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