Metal-Based Molecular Photosensitizers: From Design to Applications
A special issue of Molecules (ISSN 1420-3049). This special issue belongs to the section "Organometallic Chemistry".
Deadline for manuscript submissions: 31 October 2025 | Viewed by 701
Special Issue Editor
Interests: analytical chemistry; organic chemistry; synthesis of metal-based agents; bioimaging and therapy
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
In the field of metal coordination chemistry, metal-based agents including molecular metal complexes (MMCs), metal-organic complexes (MOCs), and metal-organic frameworks (MOFs), are promising drugs for bioimaging and therapy in preclinical research and clinical applications owing to their versatile and controllable structures. As an emerging modality for disease treatment, photodynamic therapy (PDT) takes advantage of the cytotoxic activity of reactive oxygen species (ROS) that are generated by light irradiating photosensitizers (PSs). The introduction of metal ions to construct PSs might enhance intersystem crossing (ISC) to improve ROS yield during the PDT process, thus effectively improving therapeutic efficiency and stimulating the work of several research groups towards the development of metal-based photosensitizers.
This Special Issue aims to provide a broad survey of the most recent advances in metal-based molecular photosensitizers. Original research articles or reviews that discuss new design and methodologies for the synthesis and functionalization of molecular metal complexes, metal-organic complexes or metal-organic frameworks for photodynamic therapy, and their potential applications in different fields are welcome.
Dr. Yao Sun
Guest Editor
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Keywords
- photosensitizers
- molecular metal complexes
- metal-organic complexes
- metal-organic frameworks
- photodynamic therapy
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