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Special Issue "Heterocyclic Chemistry in the Footsteps of the Graoully—In Honour of Gilbert Kirsch on the Occasion of His 75th Birthday"

A special issue of Molecules (ISSN 1420-3049).

Deadline for manuscript submissions: 31 January 2022.

Special Issue Editors

Prof. Dr. Claus Jacob
Guest Editor
Division of Bioorganic Chemistry, School of Pharmacy, Saarland University, D-66123 Saarbruecken, Germany
Interests: bioorganic chemistry; catalytic sensor/effector agents; epistemology; intracellular diagnostics; nanotechnology; natural products; reactive sulfur and selenium species; redox regulation via the cellular thiolstat
Special Issues and Collections in MDPI journals
Prof. Dr. Patrick Chaimbault
Guest Editor
Laboratoire de Chimie et Physique - Approche Multi-échelle des Milieux Complexes (EA 4632), ICPM, Université de Lorraine, France
Interests: pharmaceutical and plant analysis; high Resolution mass spectrometry; mass spectrometry hyphenated to gas chromatography; liquid chromatography and capillary electrophoresis; imaging mass spectrometry

Special Issue Information

Dear Colleagues,

Throughout history, there have been quite a few dragons roaming various scenic locations, from the rolling hills of Camelot to the ruins of the Roman amphitheater in the ancient city of Mettis, present-day Metz in Lorraine. Apart from the dragon Graoully, this region is renowned for its exquisite mirabelle, colorful history, unsuspected places with suspicious names such as Thionville, and a former and world’s only Smurf adventure park. In fact, the greater region surrounding Metz is considered by many as a jolly place where French savoir vivre meets German efficiency, the true heart and soul of Europe, with Germany, Luxembourg, Belgium, and Switzerland within cycling distance.


 Cycling across borders may also best describe the more than 50 years of synthetic chemistry associated with Gilbert Kirsch and the innovative Laboratoire d'Ingénierie Moléculaire et Biochimie Pharmacologique (LIMBP) in Metz. Born in 1947, in nearby Merlebach, a small town right at the border with the Saarland and with a long tradition in coal mining, Gilbert studied chemistry and physics at the Paul Verlaine University of Metz, graduating with a B.Sc. in 1969 and an M.Sc. degree in 1971. In 1973, he obtained his PhD degree at the same University under the supervision of Denise Cagniant with a thesis entitled “Synthesis and reactivity of sulfur-selenium heterocycles with benzo[b]selenophene skeleton. Comparison with the benzo[b]furane analogues.”

This general theme of research into chalcogen- and nitrogen heterocycles subsequently has formed the focus of the Kirsch laboratory in Metz, which Gilbert established in 1985 after a few years abroad, and which witnessed Gilbert rising through the usual professorial ranks until his retirement in 2015. For the last four decades, and with over 250 publications, numerous book chapters, international cooperations, and lectures at conferences, Gilbert Kirsch and his group at the LIMBP have been far from limp – they have turned Metz into a center of excellence, an amphitheater of organic synthetic chemistry famous within the community and esteemed by followers worldwide.

It is, therefore, our great pleasure to launch this Special Issue of Molecules in honor of Gilbert Kirsch and as a true celebration of his beloved heterocyclic chemistry. Submissions on any aspects of heterocyclic chemistry, from the synthesis to biological applications are welcome, ice-cold or hot as the Graoully, blue as a Smurf, yellow as a mirabelle or red as a cherry, moony in the sky as selenium or just simply down to earth as tellurium.

Prof. Dr. Claus Jacob
Prof. Dr. Patrick Chaimbault
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Molecules is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2000 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Published Papers

This special issue is now open for submission.
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