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Special Issue "Bioactive Compounds from Vegetable Sources"

A special issue of Molecules (ISSN 1420-3049). This special issue belongs to the section "Natural Products Chemistry".

Deadline for manuscript submissions: 31 December 2020.

Special Issue Editors

Prof. Dr. Gabriela Rapeanu
E-Mail Website
Guest Editor
Dunarea de Jos Univ Galati, Fac Food Sci Eng, 111 Domneasca St,E Bldg,Room 202, Galati 800201, Romania
Interests: Biological active compounds extraction and characterization; Degradation and inactivation kinetics of biological active compounds; Encapsulation techniques; Food authentication
Prof. Dr. Nicoleta Stănciuc
E-Mail Website
Guest Editor
Dunarea de Jos Univ Galati, Fac Food Sci Eng, 111 Domneasca St,E Bldg,Room 304, Galati 800201, Romania
Interests: Control and quality assurance of food products; Food quality and safety management. Management systems; Functional foods; Biologically active compounds; Microencapsulation; Protein denaturation mechanisms; Food traceability

Special Issue Information

Dear Colleagues,

Vegetables have a particularly high content of biologically active compounds, including phenolic acids, flavonoids, stilbenes, anthocyanins, tannins and carotenoids, with strong antioxidant activity, functional properties, antiproliferative activity, and hypocholesterolemic action.

For this Special Issue of Molecules “Bioactive Compounds from Vegetable Sources”, we invite researchers to contribute original research or review articles related to the extraction and characterization of biologically active compounds, including the evaluation of the biological properties of selected vegetable extracts, the possibility of incorporating them in targeted delivery systems, micro and nano capsule characterization, and their use for food and pharmaceutical applications.

Prof. Dr. Gabriela Rapeanu
Prof. Dr. Nicoleta Stănciuc
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Molecules is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2000 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • biologically active compounds
  • polyphenolic compounds
  • carotenoids
  • bioaccessibility and bioavailability
  • micro and nano encapsulation
  • food and pharmaceutical ingredients

Published Papers (5 papers)

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Research

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Open AccessArticle
Value-Added Lager Beer Enriched with Eggplant (Solanum melongena L.) Peel Extract
Molecules 2020, 25(3), 731; https://doi.org/10.3390/molecules25030731 - 07 Feb 2020
Abstract
Manufacturing beer with a high biological value requires identifying new methods for increasing the health-enhancing compounds level. The aim of this study was to increase the biological value of beer by adding antioxidant-rich eggplant (Solanum melongena L.) peel extract (EPE). The total [...] Read more.
Manufacturing beer with a high biological value requires identifying new methods for increasing the health-enhancing compounds level. The aim of this study was to increase the biological value of beer by adding antioxidant-rich eggplant (Solanum melongena L.) peel extract (EPE). The total phenolic content (TPC), total flavonoid content (TFC), and total monomeric anthocyanin content (TMA) were determined. Moreover, the antioxidant activity was evaluated by different radical scavenging assays. The addition of different levels of EPE resulted in a significant increase of TPC and TFC of beer samples from 0.426 to 0.631 mg GAE/mL, and from 0.065 to 0.171 mg CE/mL, respectively. The EPE-supplemented beer samples developed a reddish color because of the presence of anthocyanin pigments. The TMA content of beer varied from 0.011 to 0.083 mg D3G/mL with the level of added EPE. The HPLC analysis indicated that the anthocyanins prevailing in the eggplant peels were delphinidin-3-rutinoside, delphininidin-3-glucoside and delphinidin-3-rutinoside-5-glucoside. The radical scavenging assays indicated a linear increase of the antioxidant activity following EPE addition, without altering the physicochemical parameters of the beer. These results are promising for using the EPE as a functional ingredient for beer production. Full article
(This article belongs to the Special Issue Bioactive Compounds from Vegetable Sources)
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Open AccessArticle
Supercritical CO2 Extraction of Extracted Oil from Pistacia lentiscus L.: Mathematical Modeling, Economic Evaluation and Scale-Up
Molecules 2020, 25(1), 199; https://doi.org/10.3390/molecules25010199 - 03 Jan 2020
Abstract
In this study, the extracted oil of Pistacia lentiscus L. the Tunis region was extracted using supercritical carbon dioxide (SC-CO2) extraction containing different major components in the oil such as α-pinene (32%) and terpinene-4-ol (13%). The investigation of the effect of [...] Read more.
In this study, the extracted oil of Pistacia lentiscus L. the Tunis region was extracted using supercritical carbon dioxide (SC-CO2) extraction containing different major components in the oil such as α-pinene (32%) and terpinene-4-ol (13%). The investigation of the effect of different variables on the extraction yield with 5% level of confidence interval showed that the CO2 pressure was the main significant variable to influence the oil yield. In order to better understand the phenomena, three parameters were considered to adjust all parameters of broken and intact cell (BIC) model: grinding efficiency (G), the internal mass transfer parameter ( k S a 0 ), and the external mass transfer parameter ( k f a 0 ), which were estimated by experimental extraction curves to calculate the diffusion coefficient. From an economic point of view, we found out that the high cost of production of the extracted oil was due to the low mass of extracted oil obtained from this type of plant. Full article
(This article belongs to the Special Issue Bioactive Compounds from Vegetable Sources)
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Open AccessArticle
Correlation Study of Honey Regarding their Physicochemical Properties and Sugars and Cyclitols Content
Molecules 2020, 25(1), 34; https://doi.org/10.3390/molecules25010034 - 20 Dec 2019
Abstract
Honey is a natural sweetener, with an osmotic effect on microorganisms due to the increased sugar content and low amount of water. Cyclitols are minor constituents of honey. They play a defensive role in plants against unfavorable environmental conditions. Honey’s physicochemical properties can [...] Read more.
Honey is a natural sweetener, with an osmotic effect on microorganisms due to the increased sugar content and low amount of water. Cyclitols are minor constituents of honey. They play a defensive role in plants against unfavorable environmental conditions. Honey’s physicochemical properties can vary, resulting in a wide range of colors, flavors, scents, antioxidant activity, dissimilar values of pH, acidity, electrical conductivity, etc. Some literature regarding correlation between honey types is already available, but a comprehensive study displaying an ample evaluation of multifarious aspects is still needed. This study focuses on the correlation between 18 honey types, originating from 10 countries, collected during four years, summarizing a total of 38 samples. A total of 6 physicochemical properties and 18 target components (sugars and cyclitols) were considered as variables. A correlation analysis is presented between the investigated parameters and between honey types, together with the statistical analysis which allowed for observation of the clusters’ distribution according with the investigated variables. Full article
(This article belongs to the Special Issue Bioactive Compounds from Vegetable Sources)
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Open AccessArticle
Phytochemical Fingerprinting and In Vitro Bioassays of the Ethnomedicinal Fern Tectaria coadunata (J. Smith) C. Christensen from Central Nepal
Molecules 2019, 24(24), 4457; https://doi.org/10.3390/molecules24244457 - 05 Dec 2019
Abstract
Tectaria coadunata, an ethnomedicinal fern used in Nepal to treat a large number of diseases, has been poorly studied with regard to its phytochemical composition and possible bioactivity. This study was performed with the aim of supporting traditional medicine as a new [...] Read more.
Tectaria coadunata, an ethnomedicinal fern used in Nepal to treat a large number of diseases, has been poorly studied with regard to its phytochemical composition and possible bioactivity. This study was performed with the aim of supporting traditional medicine as a new source of bioactive constituents. Phytochemical compositions of methanol extracts were determined by nuclear magnetic resonance (NMR), liquid chromatography–diode array detector–mass spectrophotometry (LC-DAD-MS), and liquid chromatography–fluorescence–mass spectrometry. Quali-quantitative data revealed large amount of procyanidins, mainly of the A-type, as well as eriodictyol-7-O-glucuronide and luteolin-7-O-glucoronide as main constituents. The antioxidant, cytotoxic, and inhibitory activity of five enzymes that are implicated in human diseases was evaluated for the extract and fractions. High free-radical scavenging activity in 2,2-diphenyl-1-picrylhydrazyl (DPPH) and 2,2′-azino-bis(3-ethylbenzothiazoline-6-sulphonic acid) (ABTS) assays and inhibitory activities against cholinesterases and tyrosinase were observed. Furthermore, a moderate cytotoxic effect was observed on the 2008 and BxPC3 cell lines. Overall results showed potential usefulness of this fern as a source of phytochemicals for pharmaceutical uses. Full article
(This article belongs to the Special Issue Bioactive Compounds from Vegetable Sources)
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Review

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Open AccessReview
Innovative Approaches for Recovery of Phytoconstituents from Medicinal/Aromatic Plants and Biotechnological Production
Molecules 2020, 25(2), 309; https://doi.org/10.3390/molecules25020309 - 12 Jan 2020
Abstract
Continuously growing demand for plant derived therapeutic molecules obtained in a sustainable and eco-friendly manner favors biotechnological production and development of innovative extraction techniques to obtain phytoconstituents. What is more, improving and optimization of alternative techniques for the isolation of high value natural [...] Read more.
Continuously growing demand for plant derived therapeutic molecules obtained in a sustainable and eco-friendly manner favors biotechnological production and development of innovative extraction techniques to obtain phytoconstituents. What is more, improving and optimization of alternative techniques for the isolation of high value natural compounds are issues having both social and economic importance. In this critical review, the aspects regarding plant biotechnology and green downstream processing, leading to the production and extraction of increased levels of fine chemicals from both plant cell, tissue, and organ culture or fresh plant materials and the remaining by-products, are discussed. Full article
(This article belongs to the Special Issue Bioactive Compounds from Vegetable Sources)
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