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Special Issue "Exclusive Feature Papers in Natural Products Chemistry 2.0"

A special issue of Molecules (ISSN 1420-3049). This special issue belongs to the section "Natural Products Chemistry".

Deadline for manuscript submissions: 31 December 2023 | Viewed by 1507

Special Issue Editors

Department of Odontostomatologic and Specialized Clinical Sciences, Sez-Biochimica, Faculty of Medicine, Università Politecnica delle Marche, Via Ranieri 65, 60100 Ancona, Italy
Interests: nutrition; periodontal diseases/periodontitis; oxidative stress; nutrition; aging; mitochondrial function and diseases; berries (strawberry, blueberry, bilberry, cranberry, etc.); olive oil (dietary fats); honey; polyphenols; flavonoids; antioxidants; apoptosis
Special Issues, Collections and Topics in MDPI journals
Laboratory of Food Chemistry and Technology, School of Chemistry, Aristotle University of Thessaloniki, 54124 Thessaloniki, Greece
Interests: natural products' chemistry, bioactivity, and applications; olive tree products and byproducts; olive oil chemistry; analysis and quality; phytochemical analysis; nutrients and bioactive compounds; bioaccessibility and bioavailability; antioxidants as food preservatives; structure–antioxidant activity relationships
Special Issues, Collections and Topics in MDPI journals
Department of Pharmacy, University of Salerno, Via Giovanni Paolo II, 84084 Fisciano, SA, Italy
Interests: natural products; food chemistry and analytical chemistry; clinical nutrition; phytochemistry and phytotherapy; supplement and nutraceutical formulation
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleague,

It is our pleasure to announce a new Special Issue entitled “Exclusive Feature Papers in Natural Products Chemistry 2.0” an open access collection of papers (original research articles and comprehensive review papers) by the Editorial Board Members or prominent scholars invited by the Editorial Office and Guest Editors. This Special Issue aims to discuss new knowledge and cutting-edge developments in the natural product chemistry research field, in the hope of making a significant contribution to the community. We intend for this issue to be a forum for disseminating research findings as well as sharing innovative ideas in the field.

Prof. Dr. Maurizio Battino
Dr. Francesco Cacciola
Prof. Dr. Milen I. Georgiev
Prof. Dr. Vincenzo De Feo
Prof. Dr. Maria Z. Tsimidou
Prof. Dr. Luca Rastrelli
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Molecules is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • natural products
  • natural extracts
  • plant secondary metabolism
  • phytochemical analysis
  • nutrients and bioactive compounds
  • bioaccessibility and bioavailability
  • antioxidants
  • anti-inflammatories
  • antitumor and antiviral potentials

Related Special Issue

Published Papers (1 paper)

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Broccoli, Kale, and Radish Sprouts: Key Phytochemical Constituents and DPPH Free Radical Scavenging Activity
Molecules 2023, 28(11), 4266; - 23 May 2023
Cited by 2 | Viewed by 1029
Our research group previously found that broccoli sprouts possess neuroprotective effects during pregnancy. The active compound has been identified as sulforaphane (SFA), obtained from glucosinolate and glucoraphanin, which are also present in other crucifers, including kale. Sulforaphene (SFE), obtained from glucoraphenin in radish, [...] Read more.
Our research group previously found that broccoli sprouts possess neuroprotective effects during pregnancy. The active compound has been identified as sulforaphane (SFA), obtained from glucosinolate and glucoraphanin, which are also present in other crucifers, including kale. Sulforaphene (SFE), obtained from glucoraphenin in radish, also has numerous biological benefits, some of which supersede those of sulforaphane. It is likely that other components, such as phenolics, contribute to the biological activity of cruciferous vegetables. Notwithstanding their beneficial phytochemicals, crucifers are known to contain erucic acid, an antinutritional fatty acid. The aim of this research was to phytochemically examine broccoli, kale, and radish sprouts to determine good sources of SFA and SFE to inform future studies of the neuroprotective activity of cruciferous sprouts on the fetal brain, as well as product development. Three broccoli: Johnny’s Sprouting Broccoli (JSB), Gypsy F1 (GYP), and Mumm’s Sprouting Broccoli (MUM), one kale: Johnny’s Toscano Kale (JTK), and three radish cultivars: Black Spanish Round (BSR), Miyashige (MIY), and Nero Tunda (NT), were analyzed. We first quantified the glucosinolate, isothiocyanate, phenolics, and DPPH free radical scavenging activity (AOC) of one-day-old dark- and light-grown sprouts by HPLC. Radish cultivars generally had the highest glucosinolate and isothiocyanate contents, and kale had higher glucoraphanin and significantly higher sulforaphane content than the broccoli cultivars. Lighting conditions did not significantly affect the phytochemistry of the one-day-old sprouts. Based on phytochemistry and economic factors, JSB, JTK, and BSR were chosen for further sprouting for three, five, and seven days and subsequently analyzed. The three-day-old JTK and radish cultivars were identified to be the best sources of SFA and SFE, respectively, both yielding the highest levels of the respective compound while retaining high levels of phenolics and AOC and markedly lower erucic acid levels compared to one-day-old sprouts. Full article
(This article belongs to the Special Issue Exclusive Feature Papers in Natural Products Chemistry 2.0)
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