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Materials Chemistry in Europe

A special issue of Molecules (ISSN 1420-3049). This special issue belongs to the section "Materials Chemistry".

Deadline for manuscript submissions: closed (31 March 2024) | Viewed by 4262

Special Issue Editors


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Centro de Química Estrutural, Institute of Molecular Sciences, Departamento de Engenharia Química, Instituto Superior Técnico, Universidade de Lisboa, Av. Rovisco Pais, 1049-001 Lisboa, Portugal
Interests: catalyst design; C-scorpionate; single-site heterogeneous catalysis; C-H activation; CO2 fixation; biomass conversion
Special Issues, Collections and Topics in MDPI journals

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Special Issue Information

Dear Colleagues,

This Special Issue aims to present the most recent research outcomes in the field of Materials Chemistry gathered from European groups active in this research area. Potential topics include but are not limited to:

  • Advances in biomaterials;
  • Advances in nanomaterials;
  • Advances in hybrid materials;
  • Advances in core-shell materials;
  • Advances in thin films and self-assembling systems.

Types of contributions to this Special Issue can be full research articles, short communications, and reviews.

Prof. Dr. Luísa Margarida Martins
Prof. Dr. Giulio Malucelli
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Molecules is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • structure-property-processing relationships in materials
  • biomaterials
  • interfaces in material systems
  • hybrid organic-inorganic materials
  • thin films and coatings
  • self-assembling systems
  • thermal behavior
  • durability
  • fire behavior
  • circular economy in materials science

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Published Papers (2 papers)

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Research

19 pages, 6174 KiB  
Article
The Application of Ultrasmall Gold Nanoparticles (2 nm) Functionalized with Doxorubicin in Three-Dimensional Normal and Glioblastoma Organoid Models of the Blood–Brain Barrier
by Kathrin Kostka, Viktoriya Sokolova, Aya El-Taibany, Benedikt Kruse, Daniel Porada, Natalie Wolff, Oleg Prymak, Michael C. Seeds, Matthias Epple and Anthony J. Atala
Molecules 2024, 29(11), 2469; https://doi.org/10.3390/molecules29112469 - 24 May 2024
Cited by 9 | Viewed by 2180
Abstract
Among brain tumors, glioblastoma (GBM) is very challenging to treat as chemotherapeutic drugs can only penetrate the brain to a limited extent due to the blood–brain barrier (BBB). Nanoparticles can be an attractive solution for the treatment of GBM as they can transport [...] Read more.
Among brain tumors, glioblastoma (GBM) is very challenging to treat as chemotherapeutic drugs can only penetrate the brain to a limited extent due to the blood–brain barrier (BBB). Nanoparticles can be an attractive solution for the treatment of GBM as they can transport drugs across the BBB into the tumor. In this study, normal and GBM organoids comprising six brain cell types were developed and applied to study the uptake, BBB penetration, distribution, and efficacy of fluorescent, ultrasmall gold nanoparticles (AuTio-Dox-AF647s) conjugated with doxorubicin (Dox) and AlexaFluor-647-cadaverine (AF647) by confocal laser scanning microscopy (CLSM), using a mixture of dissolved doxorubicin and fluorescent AF647 molecules as a control. It was shown that the nanoparticles could easily penetrate the BBB and were found in normal and GBM organoids, while the dissolved Dox and AF647 molecules alone were unable to penetrate the BBB. Flow cytometry showed a reduction in glioblastoma cells after treatment with AuTio-Dox nanoparticles, as well as a higher uptake of these nanoparticles by GBM cells in the GBM model compared to astrocytes in the normal cell organoids. In summary, our results show that ultrasmall gold nanoparticles can serve as suitable carriers for the delivery of drugs into organoids to study BBB function. Full article
(This article belongs to the Special Issue Materials Chemistry in Europe)
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17 pages, 6936 KiB  
Article
Effect of the Addition of Naringenin Derived from Citrus on the Properties of Epoxy Resin Compositions
by Malgorzata Latos-Brozio, Anna Masek, Leszek Czechowski, Aleksandra Jastrzębska and Sebastian Miszczak
Molecules 2024, 29(2), 512; https://doi.org/10.3390/molecules29020512 - 19 Jan 2024
Cited by 1 | Viewed by 1507
Abstract
This research concerns the modification of commercially available epoxy resin with flame retardants in order to obtain aging-resistant and antimicrobial polymeric materials with a plant stabilizer dedicated to use in rail transport. Polymer compositions based on epoxy resin, fiberglass fabric, and naringenin were [...] Read more.
This research concerns the modification of commercially available epoxy resin with flame retardants in order to obtain aging-resistant and antimicrobial polymeric materials with a plant stabilizer dedicated to use in rail transport. Polymer compositions based on epoxy resin, fiberglass fabric, and naringenin were prepared. Naringenin was added as a natural stabilizer at 2, 4, and 8 phr. The materials were subjected to solar aging lasting 800 h. The hardness of the samples, surface energy, and carbonyl indexes were determined, and the color change in the composition after aging was analyzed. In addition, microscopic observations, analyses of mechanical properties, and microbiological tests were performed. The hardness determination showed that the samples retained their functional properties after solar aging. The increase in the polar component of the surface energy of all materials indicated the beginning of the degradation process of the composites. The tensile one-directional tests were carried out for plane samples taken in three directions (0, 90, and 45 degrees referred to a plate edge) before and after the aging process. The addition of naringenin did not affect the functional and surface properties of the epoxy resin-based materials. Polyphenol stabilized polymer composites, as evidenced by the results of carbonyl indexes. Moreover, the obtained samples showed good antimicrobial properties for E. coli and C. albicans in the field of testing the viability of microbial cells in contact with the tested surfaces. Full article
(This article belongs to the Special Issue Materials Chemistry in Europe)
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