Antibiotic Resistance of Aeromonas: A One Health Perspective

A special issue of Microorganisms (ISSN 2076-2607). This special issue belongs to the section "Antimicrobial Agents and Resistance".

Deadline for manuscript submissions: closed (31 October 2021) | Viewed by 4703

Special Issue Editors

Department of Biomedical Sciences, College of Health Sciences, University of Wisconsin-Milwaukee, Milwaukee, WI 53211, USA
Interests: antimicrobial resistance; aeromonads; wastewater; One Health; Escherichia coli; photodynamic inactivation
Special Issues, Collections and Topics in MDPI journals

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Co-Guest Editor
University of KwaZulu-Natal
Interests: antibiotic resistance; One Health; ESBLs; hospital; farm; wastewater

Special Issue Information

Dear Colleagues,

We invite you to submit an article to a Special Issue of the journal Microorganisms focused on ‘Antibiotic Resistance of Aeromonads: A One Health Perspective’. We are reaching out to you as an expert in this field to help us provide a comprehensive analysis of this critical topic. As you are aware, antibiotic resistance continues to be a leading global health problem, threatening the successful treatment of common microbial infections and placing a heavy economic burden on society. The One Health component acknowledges the interconnection between humans, animals, and the environment and their effect on the emergence, spread, and evolution of antimicrobial resistance. This can occur through mobile genetic elements that bridge the non-clinical and clinical environments conferring the transfer of resistance genes. Aeromonads are a group of Gram-negative, facultative anaerobic, oxidase-positive, glucose-fermenting bacilli that thrive in a variety of ecosystems. 

Importantly, aeromonads can bridge these clinical and non-clinical environments thriving in aquatic and terrestrial ecosystems where they can colonize and be pathogenic to warm- and cold-blooded species. Thus, aeromonads can be used as an indicator species to monitor antibiotic resistance. Additionally, resistance within this genus serves as a public health risk where it provides increased difficulties in treatment of disease, as well as acting as a reservoir of antimicrobial resistance genes capable of horizontal gene transfer to other pathogenic species. 

This Special Issue will enhance understanding of antimicrobial resistance from a One Health perspective among aeromonads. We welcome submissions of original research articles or comprehensive reviews concerning antimicrobial resistance among aeromonads within any natural environment or source causing an environmental impact, including but not limited to anthropogenic activity, agriculture, and aquaculture.

Dr. Troy Skwor
Guest Editor

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Keywords

  • Antimicrobial resistance 
  • Human 
  • Wastewater 
  • Aeromonas 
  • Aquatic ecosystem 
  • Agriculture 
  • Aquaculture 
  • Food

Published Papers (1 paper)

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Research

22 pages, 10314 KiB  
Article
Characterization and Antimicrobial Resistance of Environmental and Clinical Aeromonas Species Isolated from Fresh Water Ornamental Fish and Associated Farming Environment in Sri Lanka
by Pavithra M. Dhanapala, Ruwani S. Kalupahana, Anil W. Kalupahana, D.P.H. Wijesekera, Sanda A. Kottawatta, Niromi K. Jayasekera, Ayona Silva-Fletcher and S.S.S. de S. Jagoda
Microorganisms 2021, 9(10), 2106; https://doi.org/10.3390/microorganisms9102106 - 6 Oct 2021
Cited by 34 | Viewed by 3746
Abstract
The aims of this study were to characterize and investigate antimicrobial susceptibility and presence of integrons in 161 Aeromonas spp. isolated from ornamental freshwater fish farming environment, apparently healthy and diseased fish. Phylogenetic analyses of the gyrB gene sequences identified Aeromonas veronii as [...] Read more.
The aims of this study were to characterize and investigate antimicrobial susceptibility and presence of integrons in 161 Aeromonas spp. isolated from ornamental freshwater fish farming environment, apparently healthy and diseased fish. Phylogenetic analyses of the gyrB gene sequences identified Aeromonas veronii as the most abundant species (75.8%) followed by Aeromonashydrophila (9.3%), Aeromonas caviae (5%), Aeromonas jandaei (4.3%), Aeromonas dhakensis (3.7%), Aeromonas sobria (0.6%), Aeromonas media (0.6%), and Aeromonas popoffii (0.6%). Susceptibility to thirteen antimicrobials was determined and antimicrobial resistance frequencies were: amoxicillin (92.5%), enrofloxacin (67.1%), nalidixic acid (63.4%), erythromycin (26.1%), tetracycline (23.6%), imipenem (18%), trimethoprim-sulfamethoxazole (16.8%), and gentamicin (16.8%). Multi-drug resistance (MDR) was widespread among the isolates (51.6%, 83/161) with 51.6% (63/122) A. veronii isolates being MDR. In addition, 68.3% of isolates had multiple antibiotic resistance (MAR) indexes higher than 0.2, suggesting that they originated from a high-risk source of contamination where antimicrobials are often used. In all, 21.7% isolates carried class 1 integrons, with 97.1% having gene cassettes, while there were 12 isolates carrying class 2 integron gene cassettes. Our findings highlight that the aquatic environment and ornamental fish act as reservoirs of multidrug resistant Aeromonas spp. and underline the need for a judicious use of antimicrobials and timely surveillance of antimicrobial resistance (AMR) in aquaculture. Full article
(This article belongs to the Special Issue Antibiotic Resistance of Aeromonas: A One Health Perspective)
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