HIV Infections: Diagnosis and Drug Uses
A special issue of Microorganisms (ISSN 2076-2607). This special issue belongs to the section "Virology".
Deadline for manuscript submissions: 31 December 2025 | Viewed by 135
Special Issue Editor
Interests: HIV pathogenesis and prevention; host immune responses; natural products/secondary metabolites from endophytic fungi as antiviral strategies; drug resistance; antiviral screening and drug design
Special Issue Information
Dear Colleagues,
Since its discovery in 1981, HIV-1 infection remain a global health concern. Low CD4 T cell numbers result from the immune system being infected by the human immunodeficiency virus. This raises the possibility of getting sick, including with TB infections and some cancers. Blood, breast milk, semen, and vaginal secretions are among the bodily fluids by which HIV-1 is spread. Furthermore, it can be transferred to foetuses throughout pregnancy and delivery. Since the discovery of antiretroviral drugs, the prevalence of HIV-1 infection has declined, which has also resulted in a reduction in the number of AIDS-related deaths. HIV-1 infection has no known treatment, and the virus could not be eradicated from viral reservoirs with the medications available today. ART prevents the virus from spreading throughout the body. The requirement that ART be taken daily for the remainder of a person's life presents another difficulty. Significant obstacles, including drug resistance and toxicity, also beset antiretroviral therapy utilisation. Finding novel approaches to stop HIV-1 infections is crucial, as is developing medications that can specifically target the virus in the viral stage.
This Special Issue on microorganisms aims to provide an overview of the state of the science on HIV-1 infection prevention, diagnosis, and antiretroviral medication through a selection of papers. We invite manuscripts that address any element of the difficulties associated with antiretroviral medications, novel approaches to HIV prevention (vaccines), and HIV-1 diagnosis strategies.
In this Special Issue, original research articles and reviews are welcome. Research areas may include (but are not limited to) the following:
HIV prevention strategies and vaccines; new strategies in HIV-1 cure; natural products as the new antivirals; drug resistance and viral reservoirs; and diagnosis tools.
Dr. Nompumelelo Mkhwanazi
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Microorganisms is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- HIV prevention and vaccines
- drug resistance
- HIV-1 coinfections
- HIV diagnosis
- natural products as antiviral agents
- immunomodulation
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