Epidemics in Humans

A special issue of Microorganisms (ISSN 2076-2607). This special issue belongs to the section "Public Health Microbiology".

Deadline for manuscript submissions: 31 July 2025 | Viewed by 459

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Specialist of Internal Medicine & Infectious Diseases, 4th Department of Internal Medicine, University of Athens Medical School, 1 Rimini Street, Haidari, GR-12462 Athens, Greece
Interests: infectious diseases; respiratory viruses; SARS-CoV-2; COVID-19; antimicrobials; antivirals; antimicrobial resistance; emerging infections; public health
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Dear Colleagues,

This Special Issue presents a comprehensive exploration of the dynamic landscape of infectious diseases, encompassing a wide array of discoveries, underlying mechanisms, and emerging trends in the field. Through a collection of cutting-edge research articles and reviews, this Special Issue aims to shed light on the critical aspects shaping our understanding of and responses to infectious diseases.

Covering a diverse range of topics, including pathogen discovery, host–pathogen interactions, antimicrobial resistance, epidemiology, and novel treatment modalities, the contributions within this Special Issue provide valuable insights into the complex nature of infectious diseases. By elucidating the latest scientific advancements and breakthroughs, this Special Issue serves as a platform for fostering innovation and collaboration among researchers, clinicians, and public health professionals.

Moreover, discussions on One Health approaches, global disease surveillance, vaccine development, and the impact of environmental factors underscore the interconnected nature of infectious diseases and highlight the importance of multidisciplinary approaches in combatting these threats. By addressing key challenges and exploring new avenues for research and intervention, this Special Issue contributes to  ongoing efforts to control and prevent infectious diseases on a global scale.

Prof. Dr. Sotirios Tsiodras
Guest Editor

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Keywords

  • infectious diseases 
  • pathogen discovery 
  • host–pathogen interactions 
  • antimicrobial resistance 
  • epidemiology 
  • novel treatment modalities 
  • One Health approaches 
  • global disease surveillance 
  • vaccine development

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Published Papers (1 paper)

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Research

12 pages, 2699 KiB  
Communication
Incidence and Resistance Patterns of Citrobacter spp. in Switzerland: A Nationwide, Retrospective Surveillance Study (2010–2022)
by Pérince Fonton, Rebecca Grant, Michael Gasser, Niccolò Buetti, Andreas Kronenberg and Stephan Harbarth
Microorganisms 2025, 13(4), 786; https://doi.org/10.3390/microorganisms13040786 - 29 Mar 2025
Viewed by 249
Abstract
We conducted a retrospective analysis of Citrobacter spp. surveillance data from acute care hospitals that contributed Citrobacter spp. data to the national surveillance system ANRESIS from January 2010 to December 2022. The incidence of Citrobacter spp. bloodstream infections (BSIs) in Switzerland was calculated, [...] Read more.
We conducted a retrospective analysis of Citrobacter spp. surveillance data from acute care hospitals that contributed Citrobacter spp. data to the national surveillance system ANRESIS from January 2010 to December 2022. The incidence of Citrobacter spp. bloodstream infections (BSIs) in Switzerland was calculated, as well as the proportion of Citrobacter spp. isolates from urinary tract samples. We also evaluated the susceptibility of Citrobacter spp. isolates to clinically important antibiotics. From 2010 to 2022, there were 33,958 Citrobacter spp. from patients across 55 acute care hospitals continuously participating in ANRESIS included in this analysis. We observed an annual increase in the number of Citrobacter spp. BSIs, from 2.5 to 4.2 cases per 100,000 patient days (IRR: 1.04, 95% CI: 0.96–1.12). We found a higher incidence among male versus female patients (IRR: 2.47, 95% CI: 1.28–4.74) and in those aged ≥65 years, as compared with younger patients (IRR: 2.26, 95% CI: 1.18–4.32). The proportion of Citrobacter spp. among positive urinary tract samples also increased (from 18.6 to 24.7 per 1000 samples). Among ICU patients, there was a considerable proportion of resistance to third-generation cephalosporins among C. freundii isolates (26.8–44.0%), compared with non-freundii isolates (1.7–6.9%). Citrobacter spp. is gaining clinical importance in Switzerland; further studies are needed to better understand the underlying mechanisms. Full article
(This article belongs to the Special Issue Epidemics in Humans)
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