Infections, Immune Mechanisms and Host-Pathogen Interactions
A special issue of Microorganisms (ISSN 2076-2607). This special issue belongs to the section "Molecular Microbiology and Immunology".
Deadline for manuscript submissions: 31 August 2025 | Viewed by 354
Special Issue Editor
Special Issue Information
Dear Colleagues,
There are a number of ways in which pathogens have evolved to specifically evade detection and clearance by the host immune system. Mechanisms of evasion often evolve over time under circumstances of recurrent host exposure leading to pathogenic adaptations. Mechanisms of immune evasion can include strategies such as reorganizing organelles, manipulating cell signaling pathways, hijacking host cellular metabolism or sequestering into latency. These microbial survival strategies can opportunistically change a commensal bacterium into an invasive pathogen or allow viral persistence and dissemination. The approach used by a microbe can affect the severity and progression of an infection by altering pathogen virulence, interfere with the ability to establish memory responses to prevent subsequent infections or change a pathogen’s transmissibility. Understanding how different mechanisms of evasion lead not only to pathogenesis, but also host colonization, will help to identify new targets for the development of more effective therapeutics and efficacious vaccines.
The purpose of this Special Issue is to bring together a collection of research articles that provide the newest insight into mechanisms of immune evasion and manipulation across viral, parasitic and bacterial species that infect human hosts. Of particular interest are articles highlighting mechanisms in neglected or understudied diseases, including Lassa Fever Virus, Giardia, Cryptosporidium, Schistosomiasis, dengue, chikungunya, Mycobacterium ulcerans, etc.
Dr. Cristina Tato
Guest Editor
Manuscript Submission Information
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Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- immune evasion
- innate immunity
- adaptive immunity
- opportunistic
- neglected diseases
- virulence
- persistence
- metabolism
- cytokines
- therapeutic targets
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