Optimizing Antimicrobial Therapy: Real-World Evidence, Stewardship Strategies, and Outpatient Care Models

Dear Colleagues,

The optimization of antimicrobial therapy remains a major challenge in contemporary healthcare due to increasing antimicrobial resistance, growing patient complexity, and the need to balance clinical effectiveness with healthcare sustainability. While antimicrobial stewardship programs have demonstrated their value in improving prescribing practices and patient outcomes, significant gaps remain regarding the implementation of evidence-based interventions in real-world settings, particularly across outpatient and transitional care models.

This Special Issue aims to gather original research, reviews, and clinical experiences focused on optimizing antimicrobial use through real-world evidence, stewardship interventions, pharmacokinetic and pharmacodynamic approaches, innovative care pathways, and outpatient antimicrobial therapy programs. Particular interest will be given to studies evaluating effectiveness, safety, healthcare resource utilization, and patient-centered outcomes.

We invite contributions from pharmacists, microbiologists, infectious disease specialists, and healthcare researchers to advance knowledge and support the development of practical strategies that improve antimicrobial use and combat antimicrobial resistance across diverse healthcare settings.

Dr. Marta Miarons Font
Guest Editor

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