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Advanced Nanomaterials for Biological, Medical and Environmental Applications
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Advanced Nanomaterials for Biological, Medical and Environmental Applications

A special issue of Materials (ISSN 1996-1944). This special issue belongs to the section "Advanced Nanomaterials and Nanotechnology".

Deadline for manuscript submissions: closed (10 February 2023) | Viewed by 7590

Special Issue Editor

Dr. Miruna Silvia Stan

E-Mail Website
Guest Editor
Department of Biochemistry and Molecular Biology, Faculty of Biology, University of Bucharest, 050095 Bucharest, Romania
Interests: nanoparticles; photocatalysts; medical devices; oxidative stress; biomaterials
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Nanomaterials possess unique size-dependent properties that make them superior and indispensable in many areas of human activity. This Special Issue on ”Advanced Nanomaterials for Biological, Medical, and Environmental Applications” will attempt to cover the most recent advances in nanostructures, including their synthesis and characterization, and their functional and smart properties in order to be applied in biology, medicine, and environmental purposes.

The articles presented in this Special Issue will cover various topics, ranging from different techniques of synthesis for obtaining advanced nanomaterials to various applications, including the removal of biologically toxic materials, photocatalysis, biosensor diagnosis, bio-imaging probe, drug delivery, tissue regeneration, cancer treatments, and extraction and analysis of drugs and pollutants. Additionally, this Special Issue aims to discuss the commercialization prospects of nanomaterials.

Therefore, this Special Issue welcomes contributions from all researchers working on nanomaterials, as well as on their characterization, properties, and applications. Full papers, communications, and reviews are welcome.

Dr. Miruna Silvia Stan
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Materials is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • nanomaterials
  • applications
  • tissue engineering
  • biosensing
  • medical imaging
  • drug delivery
  • photocatalysts

Published Papers (5 papers)

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Research

13 pages, 4118 KiB  
Article
Effectiveness of Se/ZnO NPs in Enhancing the Antibacterial Activity of Resin-Based Dental Composites
by Iqra Saleem, Nosheen Fatima Rana, Tahreem Tanweer, Wafa Arif, Iqra Shafique, Amenah S. Alotaibi, Hanadi A. Almukhlifi, Sohad Abdulkaleg Alshareef and Farid Menaa
Materials 2022, 15(21), 7827; https://doi.org/10.3390/ma15217827 - 06 Nov 2022
Cited by 5 | Viewed by 1439
Abstract
Biofilm formation in the resin-composite interface is a major challenge for resin-based dental composites. Using doped z nanoparticles (NPs) to enhance the antibacterial properties of resin composites can be an effective approach to prevent this. The present study focused on the effectiveness of [...] Read more.
Biofilm formation in the resin-composite interface is a major challenge for resin-based dental composites. Using doped z nanoparticles (NPs) to enhance the antibacterial properties of resin composites can be an effective approach to prevent this. The present study focused on the effectiveness of Selenium-doped ZnO (Se/ZnO) NPs as an antibacterial nanofiller in resin composites and their impact on their mechanical properties. Pristine and Se/ZnO NPs were synthesized by the mechanochemical method and confirmed through UV-Vis Spectroscopy, FTIR (Fourier Transform Infrared) analysis, X-ray Diffraction (XRD) crystallography, Scanning Electron Microscopy (SEM), Energy Dispersive Spectroscopy (EDS), and Zeta analysis. The resin composites were then modified by varying concentrations of pristine and Se/ZnO NPs. A single species (S. mutans and E. faecalis) and a saliva microcosm model were utilized for antibacterial analysis. Hemolytic assay and compressive strength tests were also performed to test the modified composite resin’s cytotoxicity and mechanical strength. When incorporated into composite resin, 1% Se/ZnO NPs showed higher antibacterial activity, biocompatibility, and higher mechanical strength when compared to composites with 1% ZnO NPs. The Se/ZnO NPs has been explored for the first time as an efficient antibacterial nanofiller for resin composites and showed effectiveness at lower concentrations, and hence can be an effective candidate in preventing secondary caries by limiting biofilm formation. Full article
(This article belongs to the Special Issue Advanced Nanomaterials for Biological, Medical and Environmental Applications)
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13 pages, 2341 KiB  
Article
Highly Stable Liposomes Based on Tetraether Lipids as a Promising and Versatile Drug Delivery System
by Aybike Hemetsberger, Eduard Preis, Konrad Engelhardt, Bernd Gutberlet, Frank Runkel and Udo Bakowsky
Materials 2022, 15(19), 6995; https://doi.org/10.3390/ma15196995 - 09 Oct 2022
Cited by 4 | Viewed by 1327
Abstract
Conventional liposomes often lack stability, limiting their applicability and usage apart from intravenous routes. Nevertheless, their advantages in drug encapsulation and physicochemical properties might be helpful in oral and pulmonary drug delivery. This study investigated the feasibility and stability of liposomes containing tetraether [...] Read more.
Conventional liposomes often lack stability, limiting their applicability and usage apart from intravenous routes. Nevertheless, their advantages in drug encapsulation and physicochemical properties might be helpful in oral and pulmonary drug delivery. This study investigated the feasibility and stability of liposomes containing tetraether lipids (TEL) from Thermoplasma acidophilum. Liposomes composed of different molar ratios of TEL:Phospholipon 100H (Ph) were produced and exposed to various temperature and pH conditions. The effects on size, polydispersity index, and zeta potential were examined by dynamic and electrophoretic light scattering. Autoclaving, which was considered an additional process step after fabrication, could minimize contamination and prolong shelf life, and the stability after autoclaving was tested. Moreover, 5(6)-carboxyfluorescein leakage was measured after incubation in the presence of fetal calf serum (FCS) and lung surfactant (Alveofact). The incorporation of TEL into the liposomes significantly impacted the stability against low pH, higher temperatures, and even sterilization by autoclaving. The stability of liposomes containing TEL was confirmed by atomic force microscopy as images revealed similar sizes and morphology before and after incubation with FCS. It could be concluded that increasing the molar ratio in the TEL:Ph liposome formulations improved the structural stability against high temperature, low pH, sterilization via autoclaving, and the presence of FCS and lung surfactant. Full article
(This article belongs to the Special Issue Advanced Nanomaterials for Biological, Medical and Environmental Applications)
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22 pages, 23841 KiB  
Article
Effects of Ply Orientations and Stacking Sequences on Impact Response of Pineapple Leaf Fibre (PALF)/Carbon Hybrid Laminate Composites
by Mohd Khairul Rabani Hashim, Mohd Shukry Abdul Majid, Mohd Ridzuan Mohd Jamir, Farizul Hafiz Kasim, Hassan A. Alshahrani, Mohd Azaman Md Deros and David Hui
Materials 2022, 15(17), 6121; https://doi.org/10.3390/ma15176121 - 03 Sep 2022
Cited by 4 | Viewed by 1136
Abstract
This study investigated the impact response behaviours of pineapple leaf fibre (PALF)/carbon hybrid laminate composites for different ply orientations and stacking sequences. The laminates were manufactured using a vacuum infusion approach with various stacking sequences and ply orientations classified as symmetric quasi-isotropic, angle-ply [...] Read more.
This study investigated the impact response behaviours of pineapple leaf fibre (PALF)/carbon hybrid laminate composites for different ply orientations and stacking sequences. The laminates were manufactured using a vacuum infusion approach with various stacking sequences and ply orientations classified as symmetric quasi-isotropic, angle-ply symmetric, and cross-ply symmetric. The laminates were analysed using an IMATEK IM10 drop weight impact tester with an increment of 5 J until the samples were perforated. This investigation reveals that the overall impact properties of PALF and carbon as reinforcements were improved by a beneficial hybridised effect. The laminates with an exterior carbon layer can withstand high impact energy levels up to 27.5 J. The laminate with different stacking sequences had a lower energy transfer rate and ruptured at higher impact energy. The laminates with ply orientations of [0°/90°] and [±45°]8 exhibited 10% to 30% better energy absorption than those with ply orientations of [±45°2, 0°/90°2]s and [0°/90°2, ±45°2]s due to energy being readily transferred within the same linear ply orientation. Through visual inspection, delamination was observed to occur at the interfaces of different stacking sequences and ply orientations. Full article
(This article belongs to the Special Issue Advanced Nanomaterials for Biological, Medical and Environmental Applications)
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11 pages, 2194 KiB  
Article
Template Method for Synthesizing Hierarchically Porous MIL-101(Cr) for Efficient Removal of Large Molecular Dye
by Minmin Zou, Hexin Zhu, Ming Dong and Tian Zhao
Materials 2022, 15(16), 5763; https://doi.org/10.3390/ma15165763 - 20 Aug 2022
Cited by 2 | Viewed by 1236
Abstract
As one of the most important prototypical chromium-based MOFs, MIL-101(Cr) is well-studied and widely employed in various scientific fields. However, due to its small capture window sizes and curved internal apertures, its application in large molecular removal is quite limited, and given its [...] Read more.
As one of the most important prototypical chromium-based MOFs, MIL-101(Cr) is well-studied and widely employed in various scientific fields. However, due to its small capture window sizes and curved internal apertures, its application in large molecular removal is quite limited, and given its high stability and high synthetic temperature (>200 °C), it is difficult to achieve hierarchically porous MIL-101(Cr). In our study, hierarchically porous MIL-101(Cr) involving a high macro-/meso-/micropores ratio was designed and synthesized using acetic acid as an additive and silicon dioxide (SiO2) nanoparticles as a template. The optimal hierarchically porous MIL-101(Cr) (A-4) possessed a high specific surface area (2693 m2 g−1) and an abundant macro-/mesoporous structure with the addition of SiO2 of 200 mg. Compared with the control sample (A-0) with a less macro-/mesoporous structure, A-4 showed good adsorption properties for both coomassie brilliant blue R-250 (CBB, 82.1 mg g−1) and methylene blue (MB, 34.3 mg g−1) dyes, which were 1.36 times and 9.37 times higher than those of A-0. Moreover, A-4 also had good recyclability, and the removal rate of CBB was still higher than 85% after five cycles of adsorption. Full article
(This article belongs to the Special Issue Advanced Nanomaterials for Biological, Medical and Environmental Applications)
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12 pages, 4579 KiB  
Article
Cu-TCPP Nanosheets-Sensitized Electrode for Simultaneous Determination of Hydroquinone and Catechol
by Liudi Ji, Qi Wang, Lianhui Peng, Xiaoyu Li, Xiaoming Zhu and Peng Hu
Materials 2022, 15(13), 4625; https://doi.org/10.3390/ma15134625 - 30 Jun 2022
Cited by 5 | Viewed by 1918
Abstract
It is quite important to develop sensitive, simple, and convenient methods for the simultaneous determination of Hydroquinone (HQ) and Catechol (CC) due to their wide existence, the difficulty of degradation, and the high toxicity. Herein, Cu-TCPP nanosheets were prepared in N,N [...] Read more.
It is quite important to develop sensitive, simple, and convenient methods for the simultaneous determination of Hydroquinone (HQ) and Catechol (CC) due to their wide existence, the difficulty of degradation, and the high toxicity. Herein, Cu-TCPP nanosheets were prepared in N,N-dimethylformamide (DMF) through the solvent exfoliation method. The morphology and electrochemical performance of Cu-TCPP were characterized, revealing its stacked sheet structure with abundant pores, a fast electron transfer ability, and a large electrode active area. Using Cu-TCPP nanosheets as the sensitive material to modify the glassy carbon electrodes (Cu-TCPP/GCEs), it was found that they had an obvious enhancement effect on the electrochemical oxidation currents of HQ and CC. The signal enhancement mechanism was explored. The Cu-TCPP nanosheets not only enhanced the accumulation abilities of HQ and CC, but also improved their apparent catalytic rate, displaying high sensitivity for HQ and CC. The values of the detection limit were calculated to be 3.4 and 2.3 nM for HQ and CC. A satisfactory recovery was obtained when this method was used in measuring HQ and CC in the water samples. Full article
(This article belongs to the Special Issue Advanced Nanomaterials for Biological, Medical and Environmental Applications)
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