Advanced Systems in Targeted Alpha Particle Therapy
A special issue of Materials (ISSN 1996-1944). This special issue belongs to the section "Advanced Nanomaterials and Nanotechnology".
Deadline for manuscript submissions: closed (10 August 2022) | Viewed by 8972
Special Issue Editor
Special Issue Information
Dear Colleagues,
It has now been almost 30 years of research and development efforts in the rediscovered field of targeted alpha particle therapy. Many novel isotope production methods, new targeting molecules, and nanocarriers together with preclinical or clinical trials and first-in-patient studies have moved this field forward by leaps and bounds. This successful progress has resulted in the global acceptance of alpha emitters, like the 223RaCl2 or 225Ac-PSMA-617, powerful tools in clinical praxis, and experimental cancer treatment. Targeted alpha particle therapy (TAT) has become a regular therapeutic modality in the treatment of cancer.
This Special Issue focuses on the latest innovations and studies in the field of TAT, including the preparation and testing of novel carriers, targeting systems, and medical devices, particularly those exploiting or suppressing the nuclear recoil effect in so-called in vivo radionuclide generators. In vitro stability and in vivo biodistribution studies, dosimetric studies, therapeutic efficacy determinations in various models, clinical trials, and other related research are welcome as full papers, communications, or reviews.
Prof. Ján Kozempel
Guest Editor
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Keywords
- Alpha particle
- Chain decay
- In vivo generators
- Nuclear recoil effect
- Nanomaterials
- Carriers
- Radiopharmacy
- targeted alpha therapy
- TAT
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