Nanoparticles for Biomedical Applications: Synthesis and Fabrication

Dear Colleagues,

The current era of drug resistance has obliged researchers to shift the paradigm of drug development towards nanotechnological innovations. Nano-innovations have been explored to design, fabricate and synthesize nanoparticles for different biomedical applications. Interestingly, during the last decade, nanoparticles have been applied to confront various patho-aspects of infectious as well as non-infectious diseases. They have acted as an excellent delivery vehicle for different drug moeity without compromising their inherent therapeutic potential. In addition to acting as delivery vehicles, some nanoparticles have provided add-on advantages to synergize or maximize the therapeutic effect of the carried drug. Nano-researchers have also applied innovative approaches to perform the synthesis and subsequent modification of inorganic or organic nanoparticles by green chemistry/ chemicals. Green synthesis approaches are preferred in order to avoid the probability of imperceptible alterations in results due to residual chemicals. However, everything has its pros and cons: green synthesis approaches, specifically using herbal extracts, present a dilemma for the researchers, as they must define the exact compounds/enzymes involved in the synthesis and fabrication due to plethora of compounds in a single extract. Scientists have worked diligently to innovate the methods of synthesis and fabrication of nanoparticles to provide some effective nano-therapy or nano-diagnostic tools for the community. Still, the fate and toxicity aspects are the underexplored part for effective nanoparticles applications. The present Special Issue will cover original review and research articles pertinent to novel methods of nanoparticles synthesis and fabrication for their biomedical applications.

Dr. Syed Mohd Danish Rizvi
Dr. Amr S. Abu Lila
Guest Editors

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