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Development of Polymeric Materials for Biomedical Application

A special issue of Materials (ISSN 1996-1944). This special issue belongs to the section "Polymeric Materials".

Deadline for manuscript submissions: 20 October 2025 | Viewed by 2544

Special Issue Editor


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Guest Editor
School of Chemical Engineering and Technology (SCET), Xi'an Jiaotong University, Xi'an 710049, China
Interests: biomaterials; non-viral gene delivery vectors; hyperbranched polymers; cyclized polymers; controlled/living polymerization
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Special Issue Information

Dear Colleagues,

Among the various synthetic materials, polymers are particularly promising for biomedical applications because of their wide monomer availability, diversity in functionalities, ease of synthesis and large-scale production, excellent biocompatibility and mechanical strength. Recent advances in polymer chemistry have created powerful platforms for manipulating the chemical composition and topological structures and ultimately their biological functions in tissue engineering applications. For example, depending on the tissue microenvironment, different stimulus-sensitive polymers (e.g., pH, temperature, reactive oxygen species, acidity, etc.) have been developed to produce smart hydrogels for the treatment of chronic wounds and achieve accelerated wound healing, or to target doxrubicin into cancer tissues, with improved therapeutic efficiency and reduced side effects observed. These advances have brought synthetic polymers ever closer to their potential in biomedicine. Therefore, the development of synthetic polymers with tailored chemical composition and topological structure along with various functionalities using advanced synthesis strategies is of great importance to accelerate the maturation of biotechnology and transfer it from the laboratory to the bedside. The aim of this Special Issue is to present recent advances in the field, where synthetic polymers are indispensable, with the expectation of providing new insights into the development of clinically applicable polymeric biomaterials. The guest editors are soliciting original research articles and reviews that cover the emerging strategies for polymer synthesis, new applications of synthetic polymers in various areas of biomedicine, exciting new results both in vitro and in vivo, and potential challenges associated with translating synthetic polymers into the clinic.

Prof. Dr. Dezhong Zhou
Guest Editor

Manuscript Submission Information

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Keywords

  • biomaterial
  • polymer synthesis
  • polymer functionalization
  • drug delivery
  • tissue engineering
  • bioimaging

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Published Papers (1 paper)

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Review

25 pages, 2437 KiB  
Review
A Review of Chitosan-Based Materials for Biomedical, Food, and Water Treatment Applications
by Dan Chicea and Alexandra Nicolae-Maranciuc
Materials 2024, 17(23), 5770; https://doi.org/10.3390/ma17235770 - 25 Nov 2024
Cited by 5 | Viewed by 2096
Abstract
Chitosan, a natural biopolymer with excellent biocompatibility, biodegradability, and modifiable structure, has broad applications in regenerative medicine, tissue engineering, food packaging, and environmental technology. Its abundance, solubility in acidic solutions, and capacity for chemical modification make it highly adaptable for creating specialized derivatives [...] Read more.
Chitosan, a natural biopolymer with excellent biocompatibility, biodegradability, and modifiable structure, has broad applications in regenerative medicine, tissue engineering, food packaging, and environmental technology. Its abundance, solubility in acidic solutions, and capacity for chemical modification make it highly adaptable for creating specialized derivatives with enhanced properties. Recent advances have demonstrated chitosan’s efficacy in composite systems for tissue regeneration, drug delivery, and antimicrobial applications. This review examines chitosan’s unique properties, with a focus on its antibacterial activity as influenced by factors like pH, concentration, molecular weight, and deacetylation degree. Additionally, chitosan’s potential as a sustainable, non-toxic material for eco-friendly packaging and water treatment is explored, highlighting the growing interest in chitosan composites with other polymers and metallic nanoparticles for enhanced biomedical and environmental applications. Full article
(This article belongs to the Special Issue Development of Polymeric Materials for Biomedical Application)
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