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Special Issue "Cell Stress, Canonical and Non-Canonical Cell Death Modalities by Marine Natural Compounds and Derivatives"
A special issue of Marine Drugs (ISSN 1660-3397).
Deadline for manuscript submissions: closed (10 November 2019).
This Special Issue will focus on the discovery of novel cytostatic and cytotoxic agents of marine origin, with a focus on the cellular mechanisms the lead to cell cycle inhibition, cell stress, and diverse cell death modalities.
By now, programmed cell death modalities that use non-canonical pathways different from the well-established apoptotic mechanisms are beginning to be better understood. Considering that many cancer types can develop resistance mechanisms against apoptotic cell death, pharmacologically active compounds, in particular of marine origins could be new sources and provide ideas for drugs triggering cell death modalities including controlled necrosis, parthanatos, ferroptosis and more.
Interestingly, compounds able to trigger stress leading to ER stress or autophagic stress responses were recently described also to trigger hallmarks of immunogenic cell death when dying cells liberate so-called danger associated molecular patterns. Marine compounds remain largely unexplored for their capacities to activate such cell death modalities, and innovating contributions in this field are highly welcome.
Prof. Dr. Marc Diederich
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Marine Drugs is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2000 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- Controlled necrosis
- Endoplasmic reticulum stress
- Immunogenic cell death