Special Issue "Antitumor Compounds from Marine Invertebrates"
A special issue of Marine Drugs (ISSN 1660-3397).
Deadline for manuscript submissions: closed (23 December 2019).
Interests: marine invertebrates; natural products extraction; natural product isolation; bioactive compounds; chemotaxonomy; quorum sensing; anticancer drugs
Special Issues and Collections in MDPI journals
Since the discovery of the cytarabine derived from the spongothymidine isolated from the sponge Cryptotethya crypta in the 1950s, marine invertebrates have been an amazing source of innovative molecules, particularly in the field of anti-cancer drugs. Developed in the very first place to act for the survival of organisms in their environment, and refined by the evolution and adaptation needs of these often sessile and soft animals, these compounds are of unequalled originality. These molecules have most often been detected by screening on cellular targets, but the fine analysis of complex extracts leads to the isolation and identification of active principles, but also often to the isolation of analogues allowing better understanding of the mode of action of molecules and of the structural patterns essential to their activity.
We invite you to submit manuscripts for this Special Issue for reviews and original research articles describing novel naturally-occurring molecules and their close derivatives of anticancer interest, their cellular target, mode of action and structure-activity relationships, and their in vivo activities where appropriate.
Dr. Cécile Debitus
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Marine Drugs is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2400 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- Cancer cell lines
- Extraction and analysis
- Marine invertebrate
- Marine natural products
- Mechanism of action
- Molecular target
- Target based screening