New Insight to Overcome Tumor Resistance: Molecular and Cellular Mechanism

Dear Colleagues,

This Special Issue focuses on translational science in the hopes of shedding light on overcoming novel tumour therapy resistance. In fact, acquired drug resistance is one of the main restrictions to the efficacious treatment of cancer. There are many data showing that resistance results from drug exclusion, drug metabolism, and modification of the drug target by mutation or overexpression. Depending on the therapy, one or more genetic or epigenetic modulations are required to confer resistance to treatment.

The editor already works in a translational team from bench to bedside. She welcome submissions from researchers involved in basic cancer research but also in clinical activities. She has a deep knowledge of cancer therapy and target therapy such as tyrosine kinase and cyclin-kinases inhibitor, examined with the most different methods, biochemistry, immunohistochemistry, immunofluorescence, RT-qPCR, NGS, etc. It is required to have a clear understanding of tumour cells, and to clarify the ways that lead to therapy resistance from cell lines to clinical trials. Reviews and original papers are both welcome.

Dr. Nicoletta Cordani
Dr. Emanuela Grassilli 
Dr. Geeta Sharma
Guest Editors

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