Motor Neuron Disease

Dear Colleagues,

We are delighted to announce a call for submissions to a Special Issue of Life on the topic of “Motor Neuron Diseases”.

Motor neuron diseases are a heterogenous group of diseases characterized by the underlying degeneration of motor neurons which diversely contributes to several pathomechanisms at play in affected individuals.

This Special Issue looks to update and advance the current knowledge on motor neuron diseases’ epidemiology, clinical and biological signatures, mechanisms, and treatments by gathering a collection of high-quality review and primary research articles.

The suggested potential topics include but are not restricted to the following: (i) the epidemiological and clinical characteristics of motor neuron diseases; (ii) genetic, environmental and other risk factors; and (iii) evaluation of the impact of interventions, including pharmaceutical and nonpharmaceutical approaches.

Papers providing new insights into mechanisms of mitochondrial dysfunction, neuroinflammation, protein misfolding, cellular trafficking dysfunction, and oxidative stress in the context of motor neuron diseases are welcome.

Finally, we encourage contributions highlighting overlapping genetic and clinical features with other neurodegenerative diseases, such as dementia, parkinsonism, and psychiatric or immune-mediated diseases.

Dr. Jessica Mandrioli
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Life is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.