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Life
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Novel Therapeutic Approaches and Tissue Engineering in Dentistry
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Novel Therapeutic Approaches and Tissue Engineering in Dentistry

A special issue of Life (ISSN 2075-1729). This special issue belongs to the section "Medical Research".

Deadline for manuscript submissions: closed (22 October 2022) | Viewed by 4960

Special Issue Editors

Dr. Kinga Grzech-Leśniak

E-Mail Website1 Website2
Guest Editor
Department of Oral Surgery, Wroclaw Medical University, 50-367 Wrocław, Poland
Interests: dental lasers; decontamination; laser surface cleaning; dentistry; periodontics; prosthodontics; implantology; photobiomodulation; bone surgery; bone regenerations; periodontal therapy
Special Issues, Collections and Topics in MDPI journals
Dr. Jacek Matys

E-Mail Website
Guest Editor
Dental Surgery Department, Wroclaw Medical University, 50-367 Wrocław, Poland
Interests: medical and dental lasers; laser surface processing; laser decontamination; laser ablation; laser in bone surgery; photobiomodulation
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

We are delighted to be able to invite you to submit a manuscript to the forthcoming Special Issue, “New Advances in Dentistry”, for the journal /Life/ (IF: 3.817). This Special Issue covers a wide variety of topics in dentistry, from basic and applied research to a laboratory, pre-clinical and clinical applications related to using various modern device and materials in dentistry.

The application of the new advanced device as laser technology, CAD/CAM, CBCT, and materials in dentistry allows novel applications pre-clinical and clinical usage in various dental branches, e.g., conservative dentistry, endodontics, prosthetics, periodontology, orthodontics, surgery, and implantology. This Special Issue will accept the most advanced research and improvements in regenerative materials for conservative dentistry, endodontics, and implantology. Also, studies that cover biological safeness in the dental office will be accepted.

Furthermore, special attention will be paid to new procedures and approaches of laser technology when using various wavelengths and photobiomodulation therapy, enhancing tissue repairing and healing in dental surgery, endodontic, prosthetic, orthodontic, and periodontal treatment. Study displaying the effects of laser light and describing precisely the laser parameters, e.g., power, energy, fluence, power density, wavelength, pulse duration, repetition rate, and exposure time, will also be considered. (Please read the reference: DOI:10.7860/JCDR/2015/15561.6955)

Related publications in Life:

Photobiomodulation Therapy Applied after 6 Months for the Management of a Severe Inferior Alveolar Nerve Injury. Life 2021, 11(12), 1420; https://doi.org/10.3390/life11121420

Dr. Kinga Grzech-Leśniak
Dr. Jacek Matys
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Life is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • dentistry
  • CAD/CAM
  • CBCT
  • implantology
  • materials
  • lasers
  • biological safeness
  • tissues
  • cells
  • healing

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Published Papers (2 papers)

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Research

11 pages, 24228 KiB  
Article
Biomechanical Comparison of Asymmetric Implant Configurations for All-on-Four Treatment Using Three-Dimensional Finite Element Analysis
by Onur Gönül, Ahmet Çicek, İbrahim Murat Afat, Emine Tuna Akdoğan and Onur Atalı
Life 2022, 12(12), 1963; https://doi.org/10.3390/life12121963 - 23 Nov 2022
Cited by 1 | Viewed by 1887
Abstract
The aim of this study is to examine the effect of unilaterally more posterior placement of implants (Straumann BLT 4.1 mm in diameter and 12 mm long) applied according to the all-on-four concept on the stress distribution on bone, implants, and other prosthetic [...] Read more.
The aim of this study is to examine the effect of unilaterally more posterior placement of implants (Straumann BLT 4.1 mm in diameter and 12 mm long) applied according to the all-on-four concept on the stress distribution on bone, implants, and other prosthetic components, using the finite element analysis method. Three scenarios were modelled: For Model 1 (M1), anterior implants were placed symmetrically perpendicular to the bone in the right and left lateral incisor region, while the necks of the posterior implants placed symmetrically in the second premolar region were angled at 30 degrees. For Model 2 (M2) the implant in the left second premolar region was placed to the first molar region unilaterally. For Model 3 (M3) the implant in the left lateral incisor region was placed to the canine region unilaterally. Vertical and oblique forces (100 N) were applied in the right first molar region. The von Mises and maximum (Pmax) and minimum (Pmin) principal stresses were obtained. The highest stress concentration on the cortical bone was observed in the second premolar region in all models when oblique forces were applied. M1 was highest (8.992 MPa) followed closely by M3 (8.780 MPa) and M2 was lowest (3.692 MPa). The highest stress concentration on the prosthetic parts was observed in this framework when oblique forces were applied. M2 was highest (621.43 MPa) followed by M3 (409.16 MPa) and the lowest was M1 (309.43 MPa). It is thought that placing the implant further posterior to first molar region may prevent the bone resorption that occurs with high stress around the crestal bone. However, increased stress on the implants and prosthetic parts may lead to failures. Full article
(This article belongs to the Special Issue Novel Therapeutic Approaches and Tissue Engineering in Dentistry)
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12 pages, 2347 KiB  
Article
The Potential Role of a Surface-Modified Additive-Manufactured Healing Abutment on the Expression of Integrins α2, β1, αv, and β6 in the Peri-Implant Mucosa: A Preliminary Human Study
by Leandro Amadeu Roth, Marta Ferreira Bastos, Marcelo A. Melo, Valentim A. R. Barão, Raphael C. Costa, Gabriela Giro, João Gabriel Silva Souza, Kinga Grzech-Leśniak and Jamil Awad Shibli
Life 2022, 12(7), 937; https://doi.org/10.3390/life12070937 - 22 Jun 2022
Cited by 3 | Viewed by 1907
Abstract
The stability of peri-implant soft tissues is essential for long-term success. Integrins play a vital role in biological processes through developing and maintaining cell interactions; however, few studies have evaluated the effects of modifications to abutment surfaces on cell adhesion across integrin expression. [...] Read more.
The stability of peri-implant soft tissues is essential for long-term success. Integrins play a vital role in biological processes through developing and maintaining cell interactions; however, few studies have evaluated the effects of modifications to abutment surfaces on cell adhesion across integrin expression. Therefore, this pilot study assessed the influence of different surface topographies of titanium healing abutments prepared by additive manufacturing (AM) on the gene expression levels of the integrin subunits α2, β1, αv, and β6 in the human peri-implant mucosa. Thirteen healthy adults were included. Depending on the number of required implants, the subjects were distributed in different groups as a function of healing abutment topography: group 1 (fully rough surface); group 2 (upper machined + lower rough); group 3 (rough upper surface + lower machined); group 4 (fully machined). A total of 40 samples (n = 10/group) of the peri-implant mucosa around the abutments were collected 30 days after implant placement, and subsequently, the gene expression levels were evaluated using real-time PCR. The levels of gene expression of β1-subunit integrin were upregulated for individuals receiving fully rough surface abutments compared with the other surface topographies (p < 0.05). However, the healing abutment topography did not affect the gene expression levels of the α2, αv, and β6 integrin subunits in the human peri-implant mucosa (p > 0.05). This preliminary study suggested that controlled modifications of the surface topography of titanium healing abutments produced by AM may influence the quality of the peri-implant mucosa in the early stages of the soft tissue healing process. Full article
(This article belongs to the Special Issue Novel Therapeutic Approaches and Tissue Engineering in Dentistry)
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