Special Issue "Origin of Life in Chemically Complex Messy Environments (Volume II)"

A special issue of Life (ISSN 2075-1729). This special issue belongs to the section "Origin of Life".

Deadline for manuscript submissions: 20 June 2023 | Viewed by 88

Special Issue Editors

Chemical and Biomolecular Engineering, University of California, Los Angeles, CA 90095, USA
Interests: origin of life; prebiotic evolution; RNA world; minimal synthetic cells; molecular biology; protein and RNA biophysics; macromolecular crowding and confinement; UV damage; fluorescence spectroscopy
Special Issues, Collections and Topics in MDPI journals
Chemical and Biomolecular Engineering, University of California, Los Angeles, CA 90095, USA
Interests: origin of life; RNA world; early evolution of life
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

The first volume of the Special Issue “Origin of Life in Chemically Complex Messy Environments” (https://www.mdpi.com/journal/life/special_issues/Origin_of_Life ) was a success, and it is our pleasure to announce the second volume.

Traditionally, the vast majority of prebiotic chemistry research has consisted of experiments focused on the behavior of a restricted spectrum of organic molecules, usually studying the components of life separately, where the results are limited by the simulated scenario, also described as "clean and isolated" experiments. However, research on the origin of life needs to be expanded in order to enable continuous progress in the field. Considering the prebiotic Earth four billion years ago (a messy atmosphere, in other words), a chaotic mélange of diverse starting materials appears to be realistic. As prebiotic chemists and origin-of-life researchers, we must modify our current approach and consider more chemical and geological scenarios in which both physical processes and driving forces toward primitive life formation are examined. In this Special Issue, we welcome the submission of original research papers, comprehensive reviews, and perspectives that demonstrate or summarize advances related to the origin of life in various complex chemical and prebiotically feasible environments.

Dr. Ranajay Saha
Dr. Alberto Vázquez-Salazar
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Life is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1800 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • origin of life
  • complex chemical systems
  • prebiotic chemistry
  • prebiotic metabolisms
  • chemical evolution
  • prebiotic catalysts

Published Papers

This special issue is now open for submission.
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