Advances in Space Biomedicine and Disease Pathogenesis
A special issue of Life (ISSN 2075-1729). This special issue belongs to the section "Medical Research".
Deadline for manuscript submissions: closed (26 April 2023) | Viewed by 13843
Special Issue Editors
Interests: space biomedicine; microgravity; cell biology; prostate cancer; mechanobiology
Interests: cell biology; mechanobiology; bone biology; microgravity life sciences; space nutrition and health
Interests: muscle; molecular medicine; data sciences; spaceflight hardware for biology experiments
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
From the smallest prokaryote to the largest mammal, life on Earth has evolved in a 1 g environment. So too has disease pathogenesis. At the heart of many of the pathologies that develop during spaceflight is fundamental alterations in cell biology. Physiological and cellular responses to altered gravity or mechanical forces through spaceflight or simulated microgravity experiments can be examined in a variety of systems ranging from human to animal and cellular models including mammalian cells and microorganisms within our microbiome.
This Special Issue focuses on recent advances investigating biomedicine and disease pathogenesis in space environments ranging from simulated to orbital/suborbital microgravity, and cosmic radiation exposure. These reveal novel mechanically or gravity-driven processes that influence human development and health, with key pathways initiated during the onset of disease pathogenesis providing new biomarkers to monitor cellular and physiological stress or provide targets for novel therapeutic countermeasures. This has significant benefit not only for the next generation of spacefarers, but critically, in combatting diseases on Earth that are frequently associated with aging, or deleterious effects of limited mobility. Further, manuscripts are invited in research that exploits the challenges of research in simulated or orbital/suborbital microgravity, through biomedical advancements in device miniaturization to improve biomedical diagnostic tools that have applications in remote or extreme environments, or through developments in tissue engineering.
Dr. Ian R.D. Johnson
Dr. Roxy Fournier
Prof. Dr. Nathaniel Szewczyk
Guest Editors
Manuscript Submission Information
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Keywords
- biomedicine in extreme environments.
- in vitro and in vivo models of research in space environments
- mitigation of spaceflight-induced pathophysiology
- gravitational effects on biological systems.
- radiation effects on biological systems.
- space biology
- life support systems and advances in biostasis
- development of tools and biomarkers for remote monitoring of human health
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