Molecular and Cellular Biology of Transplantation
A special issue of Life (ISSN 2075-1729). This special issue belongs to the section "Physiology and Pathology".
Deadline for manuscript submissions: closed (31 March 2025) | Viewed by 429
Special Issue Editors
Interests: xenotransplantation; regeneration; decellularization; heart valves; ex vivo lung perfusion (EVLP); lung transplantation
2. Munich Heart Alliance, German Center for Cardiovascular Research (DZHK), 81377 Munich, Germany
Interests: heart transplantation; pediatric cardiac surgery; lung transplantation
Special Issue Information
Dear Colleagues,
Despite the progress being made in gene and cell therapies, organ transplantation will continue to be the primary treatment option for end-stage organ failure. However, patients still face significant challenges, including a shortage of donor organs and a high risk of acute and chronic graft failure. In this context, this Special Issue will explore recent advancements in the field, including ex vivo organ perfusion, xenotransplantation and the application of regulatory cells such as Tregs and CAR Tregs, with a focus on overcoming or mitigating these shortcomings.
Dr. Robert Ramm
Prof. Dr. Sebastian G. Michel
Guest Editors
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Keywords
- xeno- and allotransplantation
- ex vivo perfusion
- costimulatory blockade
- CAR Treg
- accommodation
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