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Life
Special Issues
Current Issues and Future Directions for Stroke Epidemiology and Management
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Current Issues and Future Directions for Stroke Epidemiology and Management

A special issue of Life (ISSN 2075-1729). This special issue belongs to the section "Physiology and Pathology".

Deadline for manuscript submissions: closed (18 January 2023) | Viewed by 1538

Special Issue Editor

Prof. Dr. Yannick Béjot

E-Mail Website
Guest Editor
Dijon Stroke Registry, EA7460, University Hospital of Dijon, University of Burgundy, UFBC, 21000 Dijon, France
Interests: stroke; epidemiology; outcome; cognitive impairment
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

The acute management of stroke has dramatically improved over the past few years, thus contributing to a reduction in case fatality. However, stroke remains a leading cause of handicap worldwide, and the aging population and the demographic transition are associated with a dramatic rise in the number of patients suffering a stroke each year. Clinicians are confronted with stroke survivors who may present with a variety of disabilities, including fatigue, anxiety, depression, behavioral changes, or cognitive impairment, even when their global outcome was regarded as favorable. Although less visible than motor sequelae, these symptoms have a negative impact on patients’ quality of life. A better understanding of the epidemiology, contributing factors, and underlying mechanisms of patients’ outcome is needed to develop innovative dedicated preventive and therapeutic strategies.

This Special Issue aims to cover “Current Issues and Future Directions for Stroke Epidemiology and Management”. We invite researchers to contribute original and review articles based on observational or interventional clinical studies as well as experimental works, to provide new insights into stroke management.

Related special issue: 
Special Issue title: Non-motor Functional Disability after Stroke

Special Issue link: https://www.mdpi.com/journal/life/special_issues/_Stroke

Prof. Dr. Yannick Béjot
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Life is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • stroke
  • disability
  • outcome
  • fatigue
  • depression
  • therapeutics
  • prevention
  • epidemiology

Published Papers (1 paper)

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Research

15 pages, 1032 KiB  
Article
The Impact of Post-Stroke Depressive Symptoms on Cognitive Performance in Women and in Men: A 4 Month Prospective Study
by Matildes F. M. Sobreiro, Luisa Terroni, Valeri Delgado Guajardo, Patricia Ferreira Mattos, Claudia da Costa Leite, Edson Amaro, Jr., Gisela Tinone, Dan V. Iosifescu and Renerio Fraguas
Life 2023, 13(7), 1554; https://doi.org/10.3390/life13071554 - 13 Jul 2023
Cited by 1 | Viewed by 1273
Abstract
Background: Depressive symptoms have been associated with cognitive impairment after stroke, and women may be specifically affected. Objective: The aim of this study was to investigate gender-specific characteristics in the relationship between changes in depression severity and changes in cognitive performance [...] Read more.
Background: Depressive symptoms have been associated with cognitive impairment after stroke, and women may be specifically affected. Objective: The aim of this study was to investigate gender-specific characteristics in the relationship between changes in depression severity and changes in cognitive performance after stroke. Methods: We prospectively evaluated 73 patients without a previous history of depression in the first and fourth months after a first ischemic stroke. The severity of depressive symptoms was assessed using the 31-item version of the Hamilton Rating Scale for Depression, and executive function, attention, working memory, and verbal fluency were assessed using a neuropsychological battery. Results: We included 46 (63.0%) men and 27 (36.9%) women, with mean ages of 55.2 (SD ± 15.1) and 46.8 (SD ± 14.7) years, respectively. We found significant improvement in the digit span forward and Stroop dots from month 1 to month 4 post stroke for both men and women. Women, but not men, presented a correlation between changes in phonemic verbal fluency and changes in the 31-item version of the Hamilton Rating Scale for Depression scores. Improvement in depression was correlated with improvement in verbal fluency, and worsening in depression was correlated with worsening in verbal fluency. Conclusions: Our results suggest that women might be more vulnerable to the relationship between depressive symptoms and cognitive performance, and improvement of depression may be necessary for women’s improvement in phonemic verbal fluency from the first to the fourth month after a stroke. We did not adjust the results for multiple comparisons. Thus, our findings might be considered preliminary, and confirmatory studies, also focusing on specific characteristics of women that could explain these differences, are warranted. Full article
(This article belongs to the Special Issue Current Issues and Future Directions for Stroke Epidemiology and Management)
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