Genomics and Epigenomics of Human Complex Diseases

Dear Colleagues,

The knowledge on genomics has widened enormously in the last decade, enabling a better understanding of human diseases. Besides, epigenomics has emerged as the bridge between the environment and the genome, and is being studied in different contexts, including a variety of traits, cell types, tissues and environmental conditions. Additionally, we are witnessing an explosion of analytical methods that allow us to interweave and integrate OMICs data and thus rediscover how (epi)genomic layers interact with each other and with complex phenotypes. This progress, possible only through technological and analytical advances, is contributing to the search for diagnostic markers, tailored interventions and preventive approaches applicable to clinical settings in the context of human complex diseases.

This Special Issue will provide readers with cutting-edge knowledge on “Genomics and Epigenomics of Human Complex Diseases”. In particular, we aim to collect original research papers and reviews on the genomic and epigenomic profiling of complex conditions, and we will especially welcome studies integrating different OMICs and trying to go beyond traditional analytical pipelines. In this sense, purely bioinformatics work and innovative reanalysis and reinterpretation of published data will also be considered for publication, with particular emphasis on papers describing translational application to the clinic. Therefore, this collection of interdisciplinary papers about Genomics and Epigenomics of Human Complex Diseases will be a good reference for a broad range of readers, including geneticists, medical doctors, bench biologists, data analysts and genetic epidemiologists.

Dr. Nora Fernandez-Jimenez
Dr. Iraia Garcia-Santisteban
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Life is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.