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7.1
3.9
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Life
Special Issues
Behavioral Manifestations and Neural Regulation of Movements
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Behavioral Manifestations and Neural Regulation of Movements

A special issue of Life (ISSN 2075-1729). This special issue belongs to the section "Physiology and Pathology".

Deadline for manuscript submissions: closed (30 April 2026) | Viewed by 640

Editors

Dr. Luca Puce

E-Mail Website
Guest Editor
Department of Neuroscience, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health (DINOGMI), University of Genoa, 16132 Genoa, Italy
Interests: adapted physical activity; paralympic athletes; athletes with disabilities; motor disorders; sports sciences; neuroscience; neurophysiology
Special Issues, Collections and Topics in MDPI journals
Dr. Nicola Luigi Bragazzi

grade E-Mail Website
Guest Editor
Laboratory for Industrial and Applied Mathematics (LIAM), Department of Mathematics and Statistics, York University, Toronto, ON M3J 1P3, Canada
Interests: public health; mathematical modeling; statistical modeling; sports science; physical education; meta-analysis; systematic reviews
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

This Special Issue has been conceived with the aim of exploring the behavioral manifestations and neural mechanisms underlying human movements. To this end, an interdisciplinary perspective has been adopted, thereby bridging the fields of neuroscience, psychology, physiology, rehabilitation, and movement science. Human movement is not merely the output of muscular activation; rather, it is the result of complex, dynamic interactions between central and peripheral control, cognitive and emotional modulation, individual temperament traits, and environmental demands.

This Special Issue encourages the submission of original research, reviews, and methodological contributions that investigate the generation, regulation, and adaptation of motor behavior across a range of conditions, including physiological and pathological states, as well as throughout the lifespan. A particular focus will be placed on studies that examine the role of emotional states, cognitive load, executive functions, and stable personality dimensions (e.g., anxiety, emotional lability, or hyperthymia) in shaping motor performance and control strategies.

Submissions employing multimodal approaches are strongly encouraged, including but not limited to neurophysiological (e.g., EMG, EEG, and fNIRS), biomechanical, behavioral, or neurotechnological (e.g., wearable sensors, and motion tracking) approaches. Studies combining objective measurements with clinical and observational assessments are particularly welcome.

The overarching objective of this Special Issue is to cultivate a comprehensive understanding of movement as a multifaceted phenomenon encompassing the brain, body, and behavior. This integrative approach has significant potential applications across diverse domains, including basic research, clinical diagnostics, personalized rehabilitation, and performance enhancement.

We look forward to receiving your contributions.

Dr. Luca Puce
Dr. Nicola Luigi Bragazzi
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-anonymized peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Life is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • motor control
  • movement behavior
  • sensorimotor integration
  • neurophysiology
  • emotion and movement
  • cognitive-motor interaction
  • temperament
  • neurotechnology
  • rehabilitation
  • performance

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Published Papers (1 paper)

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Research

17 pages, 1579 KB  
Article
Rate-Associated Differences in Within-Session Motor-Inhibitory Performance: Exploratory Role of Affective Temperament
by Luca Puce, Gabriele Pretelli and Carlo Trompetto
Life 2026, 16(8), 1368; https://doi.org/10.3390/life16081368 - 19 Aug 2026
Viewed by 150
Abstract
Response inhibition is often summarized as a single individual score, although performance may change within a session as temporal demand and repeated exposure vary. We examined whether change in No-Go motor performance differed across stimulus-rate conditions and was associated with affective temperament in [...] Read more.
Response inhibition is often summarized as a single individual score, although performance may change within a session as temporal demand and repeated exposure vary. We examined whether change in No-Go motor performance differed across stimulus-rate conditions and was associated with affective temperament in 53 physically active participants, predominantly young adults. Participants completed three blocks of an elbow-based Go/No-Go task; four 50-stimulus series were administered at 40, 50, 60, and 70 bpm in randomized order. The analysis included 636 series-level observations and 6360 No-Go trials, including 3185 commission errors (50.1%). Commission-error occurrence was given primary interpretive priority; conditional error duration was considered complementary, and the pragmatically weighted integrated error index was treated as a secondary composite. Error burden differed across stimulus-rate conditions, and rate-by-block interactions emerged for commission-error occurrence (trial-level GEE; Wald χ2(6) = 25.96, p < 0.001), conditional error duration (Wald χ2(6) = 14.96, p = 0.021), and the integrated index (Wald χ2(6) = 30.40, p < 0.001). Direct contrasts confirmed larger Block-1-to-Block-3 reductions at 50–70 bpm than at 40 bpm. A secondary exploratory participant-level analysis suggested that higher irritable temperament was associated with a more negative Block-3-minus-Block-1 change (β = −0.82, 95% CI −1.39 to −0.26, FDR-adjusted p = 0.020), although the corresponding moderation did not survive global correction across all temperament tests. Overall, the data indicate rate-associated differences in within-session No-Go motor performance; temperament-related findings remain exploratory. Full article
(This article belongs to the Special Issue Behavioral Manifestations and Neural Regulation of Movements)
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