Neurological Disorders: Pathophysiological Mechanisms, Translational Breakthroughs, and Therapeutic Horizons
A special issue of Life (ISSN 2075-1729). This special issue belongs to the section "Medical Research".
Deadline for manuscript submissions: 31 March 2026 | Viewed by 2
Special Issue Editors
Interests: neurooncology; intraoperative fluorescence; confocal laser endomicroscopy; imaging; traumatic brain injury; skull base surgery; spine surgery
Special Issue Information
Dear Colleagues,
The Special Issue, titled “Neurological Disorders: Pathophysiological Mechanisms, Translational Breakthroughs, and Therapeutic Horizons”, will showcase cutting-edge research advancing our understanding of neurological diseases, with topics ranging from molecular mechanisms to clinical applications. This collection aims to bridge fundamental neuroscience with translational medicine, highlighting transformative discoveries that are reshaping neurological care.
Neurological disorders represent the leading cause of death and disability worldwide, affecting millions through conditions including Alzheimer’s disease, Parkinson’s disease, multiple sclerosis, and stroke. Recent breakthroughs, such as Michelle Monje and Harald Sontheimer’s pioneering work in cancer neuroscience demonstrating how gliomas integrate into neural networks, exemplify the paradigm shifts occurring in our understanding of neurological pathophysiology.
This Special Issue will encompass research across multiple domains: molecular mechanisms underlying neurodegeneration and cellular dysfunction, precision medicine approaches utilizing genetic profiling and biomarkers, immunomodulation strategies for neurological disorders, and emerging therapeutic technologies including brain–computer interfaces achieving near-conversational speeds. Particular emphasis will be placed on translational breakthroughs that bridge laboratory discoveries with clinical applications.
The collection will feature advances in digital health technologies for neurological monitoring, nanomedicine approaches for crossing the blood–brain barrier, and regenerative medicine strategies for brain repair. By addressing pathophysiological mechanisms, translational innovations, and therapeutic horizons, this Special Issue will provide a comprehensive resource for researchers, clinicians, and healthcare professionals working to advance neurological care through precision medicine and innovative therapeutic approaches.
Dr. Julius Höhne
Prof. Dr. Szabolcs Keri
Guest Editors
Manuscript Submission Information
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Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- neurological disorders
- pathophysiological mechanisms
- translational neuroscience
- precision medicine
- biomarkers
- immunotherapy
- digital health
- brain–computer interfaces
- regenerative medicine
- nanomedicine
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